I-Perampanel

-Delile

• Ngaphambi kokuthatha i-perampanel,
• I-Perampanel ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO NOKUQAPHA, yeka ukuthatha i-perampanel bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Abantu abathathe i-perampanel bakhulise ushintsho olubucayi noma olusongela impilo empilweni nasengqondweni yabo nasekuziphatheni kwabo, ikakhulukazi ukwanda kobutha noma ukuhlukumeza abanye. Tshela udokotela wakho uma ngabe uke waba nanoma yiluphi uhlobo lokugula ngengqondo noma lokuziphatha okubi. Kodwa-ke, kufanele wazi ukuthi kungenzeka ukuthuthukisa lezi zinguquko empilweni yengqondo nokuziphatha ngenkathi uthatha i-perampanel noma ngabe ungakaze ube nezinkinga ngempilo yengqondo noma ngokuziphatha esikhathini esedlule. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho khona manjalo uma uhlangabezana nanoma yiziphi izinguquko esimweni sengqondo, ekuziphatheni, noma ebuntwini ngenkathi welashwa nge-perampanel noma kuze kube yinyanga ngemuva kokumisa ukwelashwa kwakho. Udokotela wakho uzoqapha impilo yakho yengqondo eduze ngesikhathi sokwelashwa kwakho nge-perampanel, ikakhulukazi lapho uqala ukuthatha le mithi nanoma yisiphi isikhathi lapho umthamo wakho ushintshwa. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ulaka, ubutha, intukuthelo, ukukhathazeka, ukucasuka, ukuziphatha okusolisayo noma okungathembi, ukudideka, izinkinga zememori, nokucabanga ngokulimaza noma ukubulala abanye noma ukusongela noma ukuzama ukwenza kanjalo. Udokotela wakho anganciphisa umthamo wakho noma ayeke imithi yakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-perampanel futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthatha i-perampanel.

I-Perampanel isetshenziselwa ukwelapha izinhlobo ezithile zokubanjwa kokuqalwa okuncane (ukuqubuka okubandakanya ingxenye eyodwa kuphela yobuchopho) kubantu abadala nasezinganeni ezineminyaka engu-4 nangaphezulu. Ibuye isetshenziswe ngokuhlangana neminye imithi yokwelapha izinhlobo ezithile zokubanjwa kwe-tonic-clonic okuyisisekelo (okwaziwa ngaphambili ngokuthi ukuquleka okukhulu kwe-mal; ukuthathwa okubandakanya umzimba wonke) kubantu abadala nezingane ezineminyaka engu-12 noma ngaphezulu. I-Perampanel isekilasini lemithi ebizwa ngama-anticonvulsants. Isebenza ngokunciphisa umsebenzi kagesi ongajwayelekile ebuchosheni.

I-Perampanel iza njengethebhulethi futhi njengokumiswa (uketshezi) ukuthatha ngomlomo. Imvamisa kuthathwa kanye ngosuku ngesikhathi sokulala. Thatha i-perampanel ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-perampanel ngqo njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Nyakazisa ukumiswa kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo.

Njalo sebenzisa isirinji yomlomo (ngomlomo) yokuza nomzimba eza nokumiswa kwe-perampanel ukulungiselela nokukala umthamo wakho. Ungasebenzisi isipuni sasekhaya ukukala umthamo wakho.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-perampanel futhi akhuphule kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo ngesonto.

I-Perampanel ingaba umkhuba wokwakha. Ungathathi umthamo omkhulu, uthathe kaningi, noma uthathe isikhathi eside kunokuyalelwa ngudokotela wakho.

IPerampanel ingasiza ukulawula isimo sakho kepha ayiyelaphi. Ungayeki ukuthatha i-perampanel ngaphandle kokukhuluma nodokotela wakho. Uma ngokungazelelwe uyeka ukuthatha i-perampanel, ukuquleka kwakho kungahle kube kubi kakhulu. Udokotela wakho mhlawumbe uzokwehlisa umthamo wakho kancane kancane.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-perampanel,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane kwi-perampanel, noma imiphi eminye imithi, noma yiziphi izithako kumaphilisi e-perampanel noma ukumiswa ngomlomo. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imishanguzo; ama-barbiturates afana ne-phenobarbital ne-secobarbital (Seconal); imithi yokwaliwa yizifo, ukukhathazeka, ukukhwehlela nokubanda, ukugula kwengqondo, nobuhlungu; imishanguzo yokuquleka efana ne-carbamazepine (Carbatrol, Tegretol, Equetro), oxcarbazepine (Trileptal, Oxtellar), phenytoin (Dilantin, Phenytek), primidone (Mysoline), ne-topiramate (Topamax); i-rifampin (i-Rifadin); isidambisi; amaphilisi okulala; kanye nezithambisi. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-perampanel, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• kufanele wazi ukuthi i-perampanel inganciphisa ukusebenza kwezindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, noma izimila) eziqukethe i-levonorgestrel. Sebenzisa enye indlela yokulawula ukubeletha ngenkathi uthatha i-perampanel kanye nenyanga e-1 ngemuva komthamo wakho wokugcina. Buza udokotela wakho noma usokhemisi uma ungaqiniseki ukuthi ingabe uhlelo lwakho lokuzalwa luqukethe i-levonorgestrel.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• utshele udokotela wakho uma uphuza noma wake waphuza utshwala obuningi, uma usebenzisa noma wake wasebenzisa izidakamizwa zasemgwaqeni, noma uma usebenzise kakhulu imithi kadokotela. Phinda utshele udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-perampanel, shayela udokotela wakho.
• kufanele wazi ukuthi i-perampanel ingadala isizungu, ukozela, nezinkinga ngokuxhumanisa nokulinganisela. Lokhu kungakhuphula ubungozi bokuwa okungadala ukulimala kanzima, ikakhulukazi uma usukhulile. Ungashayeli imoto, sebenzisa imishini, noma uhlanganyele emisebenzini edinga ukuqapha noma ukuxhumanisa uze wazi ukuthi lo muthi ukuthinta kanjani.
• buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-perampanel. Utshwala bungenza imiphumela emibi ye-perampanel ibe yimbi kakhulu.
• kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile futhi ungazibulala (ucabange ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo) ngenkathi uthatha i-perampanel. Inani elincane labantu abadala nezingane ezineminyaka engu-5 nangaphezulu (cishe umuntu oyedwa kwabangu-500) abathathe ama-anticonvulsants afana ne-perampanel ukwelapha izimo ezahlukahlukene phakathi kwezifundo zokwelashwa baba nokuzibulala ngesikhathi belashwa. Abanye balaba bantu bahlakulele imicabango yokuzibulala nokuziphatha kusasele isonto eli-1 ngemuva kokuqala ukuphuza umuthi. Kunobungozi bokuthi ungathola ushintsho empilweni yakho yengqondo uma uthatha umuthi we-anticonvulsant njenge-perampanel, kepha kungahle kube nengozi yokuthi uzohlangabezana nezinguquko empilweni yakho yengqondo uma isimo sakho singelashwa. Wena nodokotela wakho nizonquma ukuthi izingozi zokuthatha umuthi we-anticonvulsant zinkulu yini kunezingozi zokungawuthathi umuthi. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukwethuka; ukuphazamiseka noma ukungahlaliseki; ukucasuka okusha noma okuya kuba kubi, ukukhathazeka, noma ukucindezeleka; ukwenza izinkanuko eziyingozi; ubunzima bokulala noma ukulala; ulaka, intukuthelo, noma ukuziphatha okunodlame; i-mania (i-frenzied, imood ejabule ngokungavamile); ukukhuluma noma ukucabanga ngokufuna ukuzilimaza noma ukuqeda impilo yakho; noma olunye uguquko olungajwayelekile ekuziphatheni noma emoyeni. Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile. Uma uphuthelwa umthamo ongaphezu kowodwa, xhumana nodokotela wakho.

I-Perampanel ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isiyezi noma umuzwa wokuphotha
• ukozela
• ukuqunjelwa
• isicanucanu
• ukuhlanza
• ikhanda
• ukukhathala
• ukuzuza kwesisindo
• ukucasuka
• ubuthakathaka
• izinkinga ngokuxhumanisa
• ubuhlungu bemisipha, emuva, noma obuhlangene
• ukuncipha komuzwa wokuthinta noma ukuzwa
• ukufiphala noma ukubona kabili

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO NOKUQAPHA, yeka ukuthatha i-perampanel bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka; isifuba; umkhuhlane noma izindlala ezivuvukele; ukuvuvukala kobuso noma imilenze yakho; ukuphelelwa umoya; okuphuzi kwesikhumba noma kwamehlo; noma umchamo omnyama

I-Perampanel ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungafaki ukumiswa okwesikhashana. Lahla noma ikuphi ukumiswa okungasetshenziswanga ezinsukwini ezingama-90 ngemuva kokuqala ukuvula ibhodlela.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isiyezi
• izinguquko ezingavamile ekuziphatheni noma emoyeni
• ukuyaluza
• isimilo esinolaka

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. I-Perampanel yinto elawulwayo. Okubhalwe phansi kungagcwaliswa izikhathi ezimbalwa kuphela; buza usokhemisi wakho uma unemibuzo.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Fycompa^®