Umjovo weRomosozumab-aqqg

-Delile

• Ngaphambi kokuthola umjovo we-romosozumab-aqqg,
• Umjovo weRomosozumab-aqqg ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo weRomosozumab-aqqg ungadala izinkinga zenhliziyo ezinkulu noma ezisongela impilo njengokuhlaselwa yinhliziyo noma isifo sohlangothi. Tshela udokotela wakho uma uke wahlaselwa yinhliziyo noma wahlaselwa isifo sohlangothi, ikakhulukazi uma kwenzekile ngonyaka odlule. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo ngenkathi welashwa, shayela udokotela wakho ngokushesha: ubuhlungu besifuba noma ingcindezi, ukuphefumula okuncane, ukuzwa ukukhanya, isiyezi, ikhanda, ukuba ndikindiki noma ubuthakathaka ebusweni, engalweni, noma emilenzeni, ubunzima bokukhuluma, ukubona izinguquko, noma ukulahlekelwa ibhalansi.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-romosozumab-aqqg.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-romosozumab-aqqg futhi isikhathi ngasinye lapho ugcwalisa khona incwadi kadokotela. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Umjovo weRomosozumab-aqqg usetshenziselwa ukwelapha i-osteoporosis (isimo lapho amathambo eba mncane futhi abuthakathaka futhi aphuke kalula) kwabesifazane abangemva kokuya esikhathini (abesifazane abaye babhekana noshintsho lwempilo, ukuphela kwesikhathi sokuya esikhathini) abasengozini enkulu yokuqhekeka lapho okunye ukwelashwa kwamathambo kungasizanga noma kungabekezeleleki. Umjovo weRomosozumab-aqqg usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokwandisa ukwakheka kwamathambo nokunciphisa ukuwohloka kwamathambo.

Umjovo weRomosozumab-aqqg uza njengesisombululo sokujovwa ngomgogodla (ngaphansi kwesikhumba) esiswini sakho, engalweni ephezulu, noma ethangeni. Kuvamise ukujova kanye ngenyanga umhlinzeki wezokunakekelwa kwezempilo ngemithamo eyi-12.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-romosozumab-aqqg,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-romosozumab-aqqg, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-romosozumab-aqqg. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: angiogenesis inhibitors njenge-axitinib (Inlyta), bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), noma sunitinib (Sutent); ama-bisphosphonates afana ne-alendronate (Binosto, Fosamax), etidronate, noma ibandronate (Boniva); imithi yomdlavuza yamakhemikhali; i-denosumab (i-Prolia); noma umuthi we-steroid njenge-dexamethasone, methylprednisolone (Medrol), ne-prednisone (i-Rayos). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma unamazinga aphansi e-calcium. Udokotela wakho mhlawumbe uzokutshela ukuthi ungawutholi umjovo we-romosozumab-aqqg.
• tshela udokotela wakho uma uke waba nesifo sezinso noma welashwa nge-hemodialysis (ukwelashwa ukususa udoti egazini lapho izinso zingasebenzi).
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Umjovo weRomosozumab-aqqg uvunywa kuphela ekwelashweni kwabesifazane be-postmenopausal. Uma ukhulelwa ngenkathi uthola umjovo we-romosozumab-aqqg, shayela udokotela wakho ngokushesha.
• kufanele wazi ukuthi umjovo we-romosozumab-aqqg ungadala i-osteonecrosis yomhlathi (i-ONJ, isimo esibi sethambo lomhlathi), ikakhulukazi uma udinga ukuhlinzwa noma ukwelashwa ngenkathi usebenzisa lo muthi. Udokotela wamazinyo kufanele ahlole amazinyo akho futhi enze noma yiziphi izindlela zokwelashwa ezidingekayo, kufaka phakathi ukuhlanza, ngaphambi kokuba uqale ukusebenzisa umjovo we-romosozumab-aqqg. Qiniseka ukuthi uxubha amazinyo futhi uhlanza umlomo wakho kahle ngenkathi usebenzisa umjovo we-romosozumab-aqqg. Khuluma nodokotela wakho ngaphambi kokuthola noma yikuphi ukwelashwa kwamazinyo ngenkathi usebenzisa le mithi.

Ngenkathi uthola umjovo we-romosozumab-aqqg, kubalulekile ukuthi uthole i-calcium eyanele novithamini D. Udokotela wakho angakunika izithasiselo uma ukudla ongakudli kunganele.

Uma uphuthelwa isikhathi sokuthola i-aphoyintimenti, yenza enye i-aphoyintimenti ngokushesha okukhulu. Umthamo wakho olandelayo womjovo we-romosozumab-aqqg kufanele uhlelelwe inyanga eyodwa kusukela ngosuku lomjovo wokugcina.

Umjovo weRomosozumab-aqqg ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu obuhlangene
• ubuhlungu nokubomvu endaweni yokujova

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuvuvukala kobuso, izindebe, umlomo, ulimi, noma umphimbo
• ubunzima bokugwinya noma ukuphefumula
• isifuba
• ububomvu, ukukala, noma ukuqubuka
• ethangeni elisha noma elingavamile, ubuhlungu be-hip, noma i-groin
• ukuphazamiseka kwemisipha, ukudikiza, noma amajaqamba
• ukuba ndikindiki noma ukuncinza kweminwe, izinzwane, noma umlomo

Umjovo weRomosozumab-aqqg ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Buza usokhemisi wakho noma imiphi imibuzo onayo ngomjovo we-romosozumab-aqqg.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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