Alpelisib

-Delile

• Ngaphambi kokuthatha i-alpelisib,
• I-Alpelisib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Alpelisib isetshenziswa ngokuhlangana ne-fulvestrant (Faslodex) ukwelapha uhlobo oluthile lomdlavuza webele oselusabalele ezicutshini eziseduze noma kwezinye izingxenye zomzimba kwabesifazane asebevele badlula esikhathini ('' ushintsho lwempilo, '' ukuphela kokuya esikhathini. period) noma emadodeni, umdlavuza wawo owanda kakhulu ngesikhathi noma ngemuva kwezinye izindlela zokwelashwa. U-Alpelisib usesigabeni semithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba amasiginali abangela ukuthi amangqamuzana omdlavuza ande. Lokhu kusiza ukunqanda ukusabalala kwamangqamuzana omdlavuza.

I-Alpelisib iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla kanye ngosuku inqobo nje uma udokotela wakho encoma ukwelashwa. Thatha i-alpelisib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-alpelisib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze. Ungathathi ithebhulethi ephukile, eqhekekile noma elimele.

Uma uhlanza ngemuva kokuthatha i-alpelisib, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho anganciphisa umthamo wakho we-alpelisib, akuphathe ngeminye imithi, noma aphazamise noma ayeke ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-alpelisib.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-alpelisib,

• Tshela udokotela wakho kanye nosokhemisi uma une-allerg ku-alpelisib, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-alpelisib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, noma izithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Equetro, Tegretol, abanye), cyclosporine (Gengraf, Neoral, Sandimmune), efavirenz (Sustiva, e-Atripla, Symfi), eltrombopag (Promacta), nevirapine (Viramune), phenobarbital , phenytoin (Dilantin, Phenytek), pioglitazone (Actos, e-Oseni, Duetact), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, eRifamate, Rifater), kanye ne-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-alpelisib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi i-curcumin neSt.
• utshele udokotela wakho uma ngabe uke waba nokuqubuka okunezilonda ezibomvu ezindebeni, emlonyeni noma esikhunjeni, noma ekuchithekeni, esikhunjeni; noma uke waba nesifo sikashukela noma isifo sezinso.
• utshele udokotela wakho uma wena noma umlingani wakho ukhulelwe, noma uhlela ukukhulelwa. Wena noma umlingani wakho akufanele ukhulelwe ngesikhathi sokwelashwa kwakho nge-alpelisib. Uma ungowesifazane ongakhulelwa, kuzodingeka uhlolwe ukukhulelwa ngaphambi kokuba uqale ukwelashwa, futhi kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nangesonto elilodwa ngemuva komthamo wakho wokugcina. Uma ungowesilisa onomlingani wesifazane ongakhulelwa, sebenzisa ikhondomu ngesikhathi sokwelashwa kwakho nangesonto eli-1 ngemuva komthamo wakho wokugcina. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthatha i-alpelisib, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa. Udokotela wakho angakutshela ukuthi ungancelisi ibele ngesikhathi sokwelashwa kwakho nangesonto eli-1 ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesilisa nabesifazane. Khuluma nodokotela wakho ngezingozi zokuthatha i-alpelisib.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kudlule amahora angaphezu kwayi-9 kusukela kumthamo ongabanjwanga, yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Alpelisib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukukhathala ngokweqile
• ukuncipha kokudla
• shintsha ngendlela izinto ezinambitha ngayo
• ukuncipha komzimba
• ubuhlungu besisu
• isilungulela
• ukulahleka kwezinwele
• ikhanda
• ukulunywa
• isikhumba esomile
• umlomo owomile
• ukoma kwesitho sangasese sowesifazane
• imfiva
• ukuvuvukala kwezingalo noma imilenze

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• unenkinga yokugwinya noma ukuphefumula, ukuqhuma, ukugeleza, ukushisa komzimba, noma ukushaya kwenhliziyo okusheshayo
• ukushwabana, ukukhipha isikhumba, ukuqubuka, isikhumba esibomvu, izilonda ezindebeni noma emlonyeni, umkhuhlane, izimpawu ezifana nomkhuhlane
• ukoma okwandisiwe, umlomo owomile, ukwanda kwesifiso sokulahlekelwa isisindo, ukuchama kaningi noma amanani amakhulu kunokujwayelekile, umoya onuka izithelo
• ukuphefumula, ukukhwehlela, ubuhlungu besifuba, ukuphefumula kanzima
• uhudo olunzima, umlomo owomile, amajaqamba, ubuthakathaka, ukuncipha kokuchama, ukuvuvukala kwemilenze noma amaqakala
• ukuchama kaningi, okubuhlungu, noma okuphuthumayo

I-Alpelisib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isicanucanu
• ukungabi namandla
• ukuqubuka
• ukoma okwengeziwe nokudla
• umlomo owomile
• ukuchama kaningi noma amanani amakhulu

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoku-oda ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-alpelisib. Udokotela wakho uzophinde a-ode izivivinyo ezithile zebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-alpelisib.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Piqray^®