Inaliti ye-Fam-trastuzumab deruxtecan-nxki

-Delile

• Ngaphambi kokuthola umjovo we-fam-trastuzumab deruxtecan-nxki,
• I-Fam-trastuzumab deruxtecan-nxki ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Fam-trastuzumab deruxtecan-nxki ungadala ukulimala okungathi sína noma okusongela ukuphila kwamaphaphu, kufaka phakathi isifo samaphaphu esiphakathi (isimo lapho kunokubaba kwamaphaphu) noma i-pneumonitis (ukuvuvukala kwezicubu zamaphaphu). Tshela udokotela wakho uma unesifo samaphaphu noma unenkinga yokuphefumula. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukukhwehlela okusha noma okuya kuba kubi, ukuphefumula kanzima, ukuqhuma, ukuqina kwesifuba, umkhuhlane noma ukuphefumula okuncane.

Tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthola umjovo we-fam-trastuzumab deruxtecan-nxki. Uma ukwazi ukukhulelwa, udokotela wakho angenza isivivinyo sokukhulelwa ukuze aqiniseke ukuthi awukhulelwe ngaphambi kokuthola umjovo we-fam-trastuzumab deruxtecan-nxki. Uma ungowesifazane, kufanele usebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa kwakho nezinyanga eziyi-7 ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho wesifazane kufanele nisebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa kwenu nezinyanga ezine ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthola umjovo we-fam-trastuzumab deruxtecan-nxki, shayela udokotela wakho. I-Fam-trastuzumab deruxtecan-nxki ingalimaza umbungu.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa ukuze ahlole impendulo yomzimba wakho ku-fam-trastuzumab deruxtecan-nxki.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-fam-trastuzumab deruxtecan-nxki. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngobungozi (s) bokuthola i-fam-trastuzumab deruxtecan-nxki.

Umjovo we-Fam-trastuzumab deruxtecan-nxki usetshenziselwa ukwelapha uhlobo oluthile lomdlavuza webele ongenakususwa ngokuhlinzwa noma osabalele kwezinye izingxenye zomzimba ngemuva kokungenani ezinye izindlela zokwelashwa komdlavuza webele. Ibuye isetshenziselwe ukwelapha izinhlobo ezithile zomdlavuza wesisu (umdlavuza wesisu) kubantu abadala osudlulele ezicutshini eziseduze noma kwezinye izingxenye zomzimba ngemuva kokuthola olunye ukwelashwa. I-Fam-trastuzumab deruxtecan-nxki isekilasini lemithi ebizwa ngama-anti-drug conjugates. Isebenza ngokubulala amangqamuzana omdlavuza.

I-Fam-trastuzumab deruxtecan-nxki iza njengempuphu ezoxutshwa noketshezi futhi ifakwe ngomjovo (emthanjeni) ngaphezu kwemizuzu engama-30 noma engu-90 ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Kuvamise ukujova kanye njalo emavikini ama-3 inqobo nje uma udokotela wakho encoma ukuthi uthole ukwelashwa.

Udokotela wakho angakubambezela noma ayeke ukwelashwa kwakho ngomjovo we-fam-trastuzumab deruxtecan-nxki, noma akuphathe ngemithi eyengeziwe, ngokuya ngempendulo yakho emithini kanye neminye imiphumela emibi ohlangabezana nayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-fam-trastuzumab deruxtecan-nxki,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergen ku-fam-trastuzumab deruxtecan-nxki, imishanguzo eyenziwe nge-Chinese hamster ovary cell protein, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-fam-trastuzumab deruxtecan-nxki. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe uke waba nanoma yimiphi imibandela eshiwo esigabeni ESIBALULEKILE SESEXWAYISO, umkhuhlane noma ezinye izimpawu zokutheleleka, noma uma uke wahlushwa yinhliziyo noma isifo senhliziyo.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthola umjovo we-fam-trastuzumab deruxtecan-nxki nezinyanga eziyi-7 ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala emadodeni. Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-fam-trastuzumab deruxtecan-nxki.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Fam-trastuzumab deruxtecan-nxki ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukuqunjelwa
• isifo sohudo
• izilonda ezindebeni, emlonyeni, noma emphinjeni
• ubuhlungu besisu
• isilungulela
• ukulahlekelwa isifiso sokudla
• ukulahleka kwezinwele
• ukuphuma kwamakhala
• ikhanda
• isiyezi
• ukukhathala
• iso elomile

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isikhumba esiphaphathekile noma ukuphefumula okuncane
• ukuphefumula okusha noma okuba kubi kakhulu, ukukhwehlela, ukukhathala, ukuvuvukala kwamaqakala noma imilenze, ukushaya kwenhliziyo okungafanele, ukuzuza kwesisindo, isiyezi, noma ukuquleka
• ukopha okungajwayelekile noma ukulinyazwa
• umkhuhlane, ukubanda, ukukhwehlela, noma ezinye izimpawu zokutheleleka
• ukuqubuka

I-Fam-trastuzumab deruxtecan-nxki ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana ne-fam-trastuzumab deruxtecan-nxki.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Enhertu^®