Umlobi: Randy Alexander
Usuku Lokudalwa: 23 Epreli 2021
Ukuvuselela Usuku: 18 Unovemba 2024
Anonim
LDL and VLDL Metabolism: Lipoproteins metabolism: Endogenous pathway of lipid transport
Ividiyo: LDL and VLDL Metabolism: Lipoproteins metabolism: Endogenous pathway of lipid transport

-Delile

Ukubuka konke

Ama-lipoprotein asezingeni eliphansi (LDL) nama-lipoprotein asezingeni eliphansi kakhulu (i-VLDL) yizinhlobo ezimbili ezihlukene zama-lipoprotein atholakala egazini lakho. Ama-lipoprotein ayinhlanganisela yamaprotheni nezinhlobo ezahlukahlukene zamafutha. Baphatha i-cholesterol ne-triglycerides egazini lakho.

I-cholesterol yinto enamafutha edingekayo ekwakheni amaseli. Emzimbeni, kuvame ukudala isibindi sakho ngendlela eyinkimbinkimbi. Ama-Triglycerides ngolunye uhlobo lwamafutha asetshenziselwa ukugcina amandla athe xaxa kumaseli akho.

Umehluko omkhulu phakathi kwe-VLDL ne-LDL ukuthi unamaphesenti ahlukene we-cholesterol, amaprotheni, kanye ne-triglycerides akha i-lipoprotein ngayinye. I-VLDL iqukethe ama-triglycerides amaningi. I-LDL iqukethe i-cholesterol eningi.

I-VLDL ne-LDL zombili zibhekwa njengezinhlobo ze-cholesterol "embi". Ngenkathi umzimba wakho udinga kokubili i-cholesterol ne-triglycerides ukuze usebenze, ukuba nokuningi kwawo kungadala ukuba bakhe emithanjeni yakho. Lokhu kungandisa ubungozi besifo senhliziyo nesifo sohlangothi.


Thola izinga lakho le-cholesterol elinconyiwe.

Incazelo ye-VLDL

I-VLDL idalwe esibindini sakho ukuphatha ama-triglycerides emzimbeni wakho wonke. Yenziwe ngesisindo:

Izingxenye eziyinhloko ze-VLDLAmaphesenti
cholesterol 10%
ama-triglycerides 70%
amaprotheni10%
amanye amafutha10%

Ama-triglycerides athwalwa yi-VLDL asetshenziswa ngamaseli emzimbeni ukuthola amandla. Ukudla ama-carbohydrate amaningi, noma ushukela, kunokuba ushise kungaholela kumanani amaningi we-triglycerides namazinga aphezulu e-VLDL egazini lakho. Ama-triglycerides angeziwe agcinwa kumaseli anamafutha futhi akhishwe ngokuhamba kwesikhathi lapho edingeka ukuze athole amandla.

Amazinga aphezulu e-triglycerides axhumene nokwakhiwa kwamadiphozithi anzima emithanjeni yakho. Lezi zimali zibizwa ngokuthi ama-plaque. Ukwakhiwa kweplaque kwandisa ingozi yesifo senhliziyo nesifo sohlangothi. Ochwepheshe bakholelwa ukuthi lokhu kungenxa yokuthi:

  • ukwanda kokuvuvukala
  • ukwanda komfutho wegazi
  • izinguquko kulwelwesi lwemithambo yegazi
  • amazinga aphansi we-high-density lipoprotein (HDL), i-cholesterol "enhle"

Ama-triglycerides aphezulu nawo ahlotshaniswa ne-metabolic syndrome kanye nesifo esingesona esinotshwala esinamafutha.


Incazelo ye-LDL

Enye i-VLDL iyasulwa egazini. Okunye kuguqulwa kube yi-LDL ngama-enzyme egazini. I-LDL ine-triglycerides encane namaphesenti aphezulu we-cholesterol kune-VLDL. I-LDL yakhiwe kakhulu ngesisindo:

Izingxenye eziyinhloko ze-LDLAmaphesenti
cholesterol 26%
ama-triglycerides10%
amaprotheni25%
amanye amafutha15%

I-LDL ithwala i-cholesterol emzimbeni wakho wonke. I-cholesterol eningi kakhulu emzimbeni wakho iholela emazingeni aphezulu e-LDL. Amazinga aphezulu e-LDL nawo ahlotshaniswa nokwakhiwa kocwecwe emithanjeni yakho.

Lezi zimali zingagcina ziholele ku-atherosclerosis. I-atherosclerosis yenzeka lapho ukufakwa koqwembe lukhuni futhi kwanciphisa umthambo. Lokhu kwandisa ingozi yokuba nesifo senhliziyo nokushaywa unhlangothi.

Imihlahlandlela yakamuva evela ku-American Heart Association manje igxile engcupheni ephelele yokuthuthukisa isifo senhliziyo, kunokuba kube nemiphumela ye-cholesterol ngayinye.


Amazinga akho e-cholesterol ephelele, i-LDL, ne-HDL, kanye nezinye izici ezahlukahlukene, anquma ukuthi yiziphi izindlela zokwelashwa ezingcono kakhulu kuwe.

Khuluma nodokotela wakho nge-cholesterol yakho nokuthi unganciphisa kanjani ingozi yesifo senhliziyo ngokudla, ukuzivocavoca umzimba, izinguquko zokuphila, nemithi, uma kudingeka.

Ukuhlola i-VLDL ne-LDL

Iningi labantu lizohlolelwa izinga labo le-LDL ngesikhathi sokuhlolwa komzimba. I-LDL ivame ukuhlolwa njengengxenye yokuhlolwa kwe-cholesterol.

I-American Heart Association incoma bonke abantu abangaphezu kweminyaka engama-20 ukuba bahlolwe i-cholesterol njalo eminyakeni emine kuya kweyisithupha. Amazinga e-cholesterol kungadingeka ukuthi alandelwe kaningi uma ingozi yesifo senhliziyo iphakeme noma ukuqapha noma yikuphi ukwelashwa.

Akukho ukuhlolwa okuqondile kwe-cholesterol ye-VLDL. I-VLDL ivame ukulinganiselwa ngokususelwa ezingeni lakho le-triglycerides. Ama-Triglycerides nawo avame ukuhlolwa ngokuhlolwa kwe-cholesterol.

Odokotela abaningi abazenzi izibalo ukuthola ileveli yakho ye-VLDL elinganiselwe ngaphandle kokuthi uyicele ngqo noma une:

  • ezinye izinto eziyingozi zesifo senhliziyo
  • izimo ezithile ezingavamile ze-cholesterol
  • isifo senhliziyo sokuqala

Izici ezinobungozi zesifo senhliziyo zihlanganisa:

  • ukukhula kweminyaka
  • isisindo esikhulayo
  • ukuba nesifo sikashukela noma umfutho wegazi ophezulu
  • ukuba nomlando womndeni wesifo senhliziyo
  • ukubhema
  • ukuntuleka kokuvivinya umzimba njalo
  • ukudla okungenampilo (okunamafutha ezilwane amaningi noshukela kanye nezithelo, imifino kanye nefayibha)

Indlela yokwehlisa amazinga e-VLDL ne-LDL

Amasu okwehlisa amazinga akho e-VLDL ne-LDL ayafana: khulisa ukuzivocavoca umzimba futhi udle ukudla okunhlobonhlobo okunempilo.

Ukuyeka ukubhema nokunciphisa ukuphuza utshwala nakho kungasiza. Udokotela wakho uyindawo engcono kakhulu yokuqala ukuthola izincomo ngokushintsha kwendlela yokuphila enempilo eyenzelwe wena.

Amathiphu

  • Yidla amantongomane, ukwatapheya, i-oatmeal enqunywe ngensimbi, nezinhlanzi ezinothe ngama-omega-3 fatty acids, njenge-salmon ne-halibut.
  • Gwema amafutha agcwele, atholakala ekudleni okufana nenyama yenkomo, ibhotela noshizi.
  • Ukuzivocavoca okungenani imizuzu engama-30 ngosuku.

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