Umlobi: William Ramirez
Usuku Lokudalwa: 22 Usepthemba 2021
Ukuvuselela Usuku: 1 Udisemba 2024
Anonim
Lumateperone: Mechanism of Action
Ividiyo: Lumateperone: Mechanism of Action

-Delile

Ucwaningo lukhombisile ukuthi abantu abadala asebekhulile abanenkinga yokuwohloka komqondo (ukuphazamiseka kobuchopho okuthinta ikhono lokukhumbula, ukucabanga kahle, ukuxhumana, nokwenza imisebenzi yansuku zonke futhi lokho kungadala ushintsho esimweni sengqondo nobuntu) abathatha ama-antipsychotic (imishanguzo yokugula ngengqondo) njenge-lumateperone babe nethuba elandayo lokufa ngesikhathi sokwelashwa. Abantu abadala asebekhulile abanenkinga yokuwohloka komqondo futhi bangaba nethuba elikhulu lokushaywa unhlangothi noma ukwelashwa okuncane ngesikhathi sokwelashwa.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-lumateperone.

ILumateperone isetshenziselwa ukwelapha izimpawu ze-schizophrenia (ukugula kwengqondo okubangela ukuphazamiseka noma ukucabanga okungajwayelekile, ukuphelelwa yintshisekelo empilweni, kanye nemizwelo enamandla noma engafanele). ILumateperone isekilasini lemithi ebizwa ngama-antipyychotic atypical. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.

ILumateperone iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa ngokudla kanye ngosuku. Thatha i-lumateperone ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-lumateperone njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.


ILumateperone ingasiza ekulawuleni izimpawu zakho, kepha ngeke iselaphe isimo sakho. Kungathatha amasonto ambalwa noma ngaphezulu ngaphambi kokuthi uzwe inzuzo ephelele ye-lumateperone. Qhubeka uthathe i-lumateperone noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-lumateperone ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-lumateperone,

  • Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-lumateperone, noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule we-lumateperone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: ama-antifungal athile afana ne-fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole, ne-voriconazole (Vfend); ama-antihistamine; imishanguzo yokukhathazeka, umfutho wegazi ophakeme, isifo samathumbu esibuhlungu, ukugula ngengqondo, ukugula okunyakazayo, isifo sikaParkinson, izilonda, noma izinkinga zomchamo; i-aprepitant (Hlela); i-armodafinil (i-Nuvigil); i-bosentan (iTracleer); ama-calcium channel blocker afana ne-diltiazem (Cardizem, Dilacor, Tiazac) ne-verapamil (Calan, Covera, Verelan); i-ciprofloxacin (Cipro); i-clarithromycin; i-cyclosporine (iNeoral, iSandimmune); i-erythromycin (i-Eryc); i-fluvoxamine (i-Luvox); imishanguzo ye-HIV noma i-AIDS efana ne-amprenavir (Agenerase) (ayitholakali ngokuthengisa e-US), efavirenz (Sustiva), etravirine (Intelence), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), kanye ne-saquinavir (Fortovase, Invirase) ; i-modafinil (i-Provigil); nafcillin; nefazodone; i-pioglitazone (Actos); i-prednisone (iRayos); ama-probenecid (i-Probalan); i-rifampin (i-Rifadin, i-Rimactane); isidambisi; imishanguzo yokuquleka efana ne-carbamazepine (Tegretol), i-phenytoin (i-Dilantin, i-Phenytek), ne-valproic acid; kanye nezithambisi. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingaxhumana ne-lumateperone, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
  • utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
  • utshele udokotela wakho uma uhudo olunzima noma uhlanza noma ucabanga ukuthi kungenzeka uphelelwe amanzi emzimbeni. Futhi, tshela udokotela wakho uma uke waba nesifo senhliziyo noma uke waba nesifo senhliziyo, ukuhluleka kwenhliziyo, isifo senhliziyo, ukushaya kwenhliziyo okungajwayelekile, umfutho wegazi ophakeme noma ophansi, isifo sohlangothi, noma i-ministroke; noma isiphi isimo esenza kube nzima ukuthi usigwinye; ukuquleka; unenkinga yokugcina ibhalansi yakho; isifo sikashukela; inani eliphansi lamaseli amhlophe egazi; i-dyslipidemia (amazinga aphezulu e-cholesterol); noma isifo sesibindi.
  • Tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, noma uma uhlela ukukhulelwa noma ukuncelisa. Uma ukhulelwa ngenkathi uthatha i-lumateperone, shayela udokotela wakho. ILumateperone ingadala izinkinga ezinganeni ezisanda kuzalwa ngemuva kokubeletha uma zithathwa ezinyangeni zokugcina zokukhulelwa.
  • tshela udokotela wakho uma uncelisa. Akufanele uncelise ngenkathi uthatha i-lumateperone.
  • kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesilisa nabesifazane. Khuluma nodokotela wakho ngezingozi zokuthatha i-lumateperone.
  • kufanele wazi ukuthi i-lumateperone ingakwenza ukozele. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
  • kufanele wazi ukuthi utshwala bungangezela ukozela okubangelwa yilomuthi. Ungaphuzi utshwala ngenkathi uthatha i-lumateperone.
  • kufanele wazi ukuthi i-lumateperone ingadala isiyezi, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu kusuka endaweni elele. Lokhu kuvame kakhulu lapho uqala ukuthatha i-lumateperone. Ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
  • kufanele wazi ukuthi i-lumateperone ingenza kube nzima ukuthi umzimba wakho uphole lapho kushisa kakhulu. Tshela udokotela wakho uma uhlela ukuzivocavoca umzimba noma ukuvezwa ukushisa okukhulu.
  • kufanele wazi ukuthi ungathola i-hyperglycemia (iyanda kushukela wakho wegazi) ngenkathi uthatha lo muthi, noma ngabe awunaso vele isifo sikashukela. Uma une-schizophrenia, kungenzeka ukuthi ube nesifo sikashukela kunabantu abangenayo i-schizophrenia, futhi ukuthatha i-lumateperone noma imishanguzo efanayo kungakhuphula le ngozi. Tshela udokotela wakho ngokushesha uma unanoma iyiphi yalezi zimpawu ezilandelayo ngenkathi uthatha i-lumateperone: ukoma ngokweqile, ukuchama njalo, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela ophakeme wegazi ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi: umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.

Ungaphuzi ijusi yamagilebhisi noma udle izithelo zomvini ngenkathi uthatha lo muthi.


Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula ngokudla. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ILumateperone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ukukhathala ngokweqile noma ukukhathala
  • ukuzuza kwesisindo
  • isicanucanu
  • umlomo owomile
  • isiyezi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisohlwini LWEZEXWAYISO EZIBALULEKILE noma ezigabeni EZIKHETHEKILE ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

  • ukuqubuka, isifuba, noma ukulunywa
  • izinkinga ngokuxhumanisa noma ukwanda kokuwa
  • ukunyakaza okungajwayelekile kobuso bakho noma komzimba ongeke ukwazi ukukulawula
  • umphimbo obuhlungu, umkhuhlane, ukubanda, noma ezinye izimpawu zokutheleleka
  • imfiva; imisipha eqinile; ukujuluka; ukudideka; ukujuluka; noma ukushaya kwenhliziyo okusheshayo, okushaya ngamandla, noma okungajwayelekile
  • ukuqina kwemisipha yentamo noma umphimbo; noma ukuphefumula kanzima noma ukugwinya
  • isithuthwane

ILumateperone ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.


Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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