Sacituzumab govitecan-hziy Injection

-Delile

• Ngaphambi kokuthola i-sacituzumab govitecan-hziy,
• ISacituzumab govitecan-hziy ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO nokuthi UNGAKWAZI kanjani, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

ISacituzumab govitecan-hziy ingadala ukwehla okukhulu kwenani lamaseli amhlophe egazini lakho. Udokotela wakho uzo-oda ukuhlolwa kwe-laboratory njalo ngesikhathi sokwelashwa kwakho ukubheka inani lamaseli amhlophe egazi egazini lakho. Ukwehla kwenani lamaseli amhlophe egazi emzimbeni wakho kungandisa ubungozi bokuthi uzoba nokutheleleka okungathi sína. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, amakhaza, umphimbo obuhlungu, ukuphefumula okuncane, ukukhwehlela okuqhubekayo nokucinana, ukushisa noma ubuhlungu lapho uchama, noma ezinye izimpawu zokutheleleka.

ISacituzumab govitecan-hziy ingadala isifo sohudo esibi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: indle evulekile; isifo sohudo; indle emnyama noma enegazi; izimpawu zokuphelelwa amandla kwamanzi njengamakhanda amancane, isiyezi, noma ukuquleka; noma uma ungakwazi ukuthatha uketshezi ngomlomo ngenxa yesicanucanu noma ukuhlanza. Khuluma nodokotela wakho ngalokho okufanele ukwenze uma uba nohudo nganoma yisiphi isikhathi lapho welashwa nge-sacituzumab govitecan-hziy noma uma ingalawulwa kungakapheli amahora angama-24 ngemuva kokwelashwa ngemithi yohudo.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-sacituzumab govitecan-hziy.

Khuluma nodokotela wakho ngezingozi zokuthola i-sacituzumab govitecan-hziy.

ISacituzumab govitecan-hziy isetshenziselwa ukwelapha uhlobo oluthile lomdlavuza webele kubantu abadala oselusabalalele kwezinye izingxenye zomzimba futhi seluvele seluphethwe okungenani ngeminye imithi emibili yokwelashwa ngamakhemikhali. ISacituzumab govitecan-hziy ikusigaba semithi esibizwa ngama-anti-drug conjugates. Isebenza ngokubulala amangqamuzana omdlavuza.

ISacituzumab govitecan-hziy iza njengempuphu ezoxutshwa noketshezi futhi ifakwe ngomjovo (emthanjeni) ngaphezu kwehora eli-1 ukuya kwele-3 ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa ngezinsuku 1 no-8 zomjikelezo wezinsuku ezingama-21. Umjikelezo ungaphindwa njengoba kunconywe udokotela wakho. Ubude bokwelashwa kwakho buncike ekutheni umzimba wakho uphendula kanjani emithini nakunoma imiphi imiphumela emibi ohlangabezana nayo.

Umjovo we-Sacituzumab govitecan-hziy ungadala isicanucanu, ukuhlanza, kanye ne-allergic reaction, okuvame ukwenzeka ngesikhathi sokufakwa komuthi noma kungakapheli amahora angama-24 ethola umthamo. Uzonikezwa eminye imithi yokusiza ukuvimbela nokwelapha ukusabela. Udokotela noma umhlengikazi uzokubuka ngokucophelela ngesikhathi futhi okungenani imizuzu engama-30 ngemuva kokufakwa kokunye ukuphendula emithini. Uma uhlangabezana nalezi zimpawu ezilandelayo, tshela udokotela wakho ngokushesha: isicanucanu; ukuhlanza; ukuvuvukala kobuso bakho, izindebe, ulimi, noma umphimbo; imfiva; isiyezi; ukuqhuma; Ukugodola; ukuqubuka; isifuba; ukulunywa; ukushaya; noma ukuphefumula kanzima.

Udokotela wakho anganciphisa umthamo wakho noma ayeke ukwelashwa kwakho okwesikhashana noma unomphela. Lokhu kuncike ekutheni umuthi usebenza kanjani kuwe kanye nemiphumela emibi oyitholayo. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-sacituzumab govitecan-hziy.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-sacituzumab govitecan-hziy,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-sacituzumab govitecan-hziy, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-sacituzumab govitecan-hziy. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Equetro, Teril, others), atazanavir (Reyataz, e-Evotaz), indinavir (Crixivan), irinotecan (Camptosar, Onivyde), phenobarbital, rifampin (Rifadin, in Rifater), futhi sorafenib (Nexavar). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthola umjovo we-sacituzumab govitecan-hziy. Uma ungowesifazane okwaziyo ukukhulelwa, kufanele uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nezinyanga eziyisithupha ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena kanye nomlingani wakho wesifazane kufanele nisebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa futhi izinyanga ezintathu ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthola umjovo we-sacituzumab govitecan-hziy, shayela udokotela wakho. ISacituzumab govitecan-hziy ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthola i-sacituzumab govitecan-hziy nenyanga e-1 ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesifazane. Khuluma nodokotela wakho ngezingozi zokuthola i-sacituzumab govitecan-hziy.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa isikhathi sokuthola i-sacituzumab govitecan-hziy, shayela udokotela wakho ngokushesha.

ISacituzumab govitecan-hziy ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• izilonda zomlomo
• ubuhlungu besisu
• ukukhathala
• ukulahlekelwa isifiso sokudla
• izinguquko zokunambitheka
• ukulahleka kwezinwele
• isikhumba esomile
• ikhanda
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• ubuhlungu emuva noma ngokuhlanganyela
• ubuhlungu ezingalweni noma emilenzeni
• ukuvuvukala kwezandla, amaqakala, noma izinyawo
• ubunzima bokulala noma ukulala
• isikhumba esiphaphathekile noma ukukhathala okungajwayelekile noma ubuthakathaka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO nokuthi UNGAKWAZI kanjani, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukulinyazwa okulula noma ukopha; ukuphuma ezinsinini noma emakhaleni; noma igazi emchameni noma esitulweni

ISacituzumab govitecan-hziy ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• umkhuhlane, ukubanda, ukukhwehlela, noma ezinye izimpawu zokutheleleka

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana ne-sacituzumab govitecan-hziy. Udokotela wakho angalawula izivivinyo ezithile zelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi kungenzeka yini ube nengozi eyengeziwe yemiphumela emibi evela ku-sacituzumab govitecan-hziy ngokuya ngofuzo lwakho noma ukwakheka kofuzo.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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