Thioguanine

-Delile

• Ngaphambi kokuthatha i-thioguanine,
• I-Thioguanine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Thioguanine isetshenziselwa ukwelapha i-acute myeloid leukemia (AML; uhlobo lomdlavuza oluqala kumaseli amhlophe egazi).I-Thioguanine isekilasini lemithi eyaziwa ngokuthi ama-purine analogs. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

I-Thioguanine iza njengethebhulethi yokuphuza ngomlomo imvamisa kanye ngosuku. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza onawo. Thatha i-thioguanine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-thioguanine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakhuphula noma anciphise umthamo wakho we-thioguanine ngesikhathi sokwelashwa kwakho. Lokhu kuncike ekutheni umuthi usebenza kanjani kuwe nasemiphumeleni oyitholayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Qhubeka uphuze i-thioguanine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-thioguanine ngaphandle kokukhuluma nodokotela wakho

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-thioguanine,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-thioguanine, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-thioguanine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma usuvele uthathe i-thioguanine noma i-mercaptopurine ukwelapha umdlavuza wakho. Udokotela wakho angakutshela ukuthi ungathathi i-thioguanine uma enye yale mithi ingasebenzi kahle ekulweni nomdlavuza wakho esikhathini esedlule.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-aminosalicylates afana ne-mesalamine (Apriso, Asacol, Pentasa, abanye), olsalazine (Dipentum), ne-sulfasalazine (Azulfidine). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Phinda utshele udokotela kanye nosokhemisi ngayo yonke imithi oyiphuzayo ukuze bakwazi ukubheka ukuthi ngabe ikhona yini imishanguzo yakho engakhuphula ubungozi bokuthi uzoba nokulimala kwesibindi ngesikhathi ukwelashwa kwakho nge-thioguanine.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola i-thioguanine. Uma ukhulelwa ngenkathi uthola i-thioguanine, shayela udokotela wakho. I-Thioguanine ingalimaza umbungu.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.
• kufanele wazi ukuthi ubungozi bokuthi uzoba nemiphumela emibi kakhulu ye-thioguanine bungaba bukhulu uma unesici sofuzo (esizuzwe njengefa). Udokotela wakho angalawula ukuhlolwa ngaphambi noma ngesikhathi sokwelashwa kwakho ukuze abone ukuthi unale nto engcupheni.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Phuza uketshezi oluningi ngesikhathi sokwelashwa kwakho nge-thioguanine.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Thioguanine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla noma isisindo
• izilonda emlonyeni nasemphinjeni
• ikhanda

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukukhathala okungajwayelekile noma ubuthakathaka
• ukopha okungajwayelekile noma ukulinyazwa
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• ukuvuvukala kwendawo yesisu
• ubuhlungu besisu, ikakhulukazi engxenyeni efanele yesisu
• ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuhlanza okunegazi
• ezimnyama, ezilindile noma ezinezihlalo ezinegazi
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
• ukuphelelwa umoya
• ubumhlophe

I-Thioguanine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• ukujuluka okweqile
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukopha okungajwayelekile noma ukulinyazwa
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-thioguanine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Tabloid^®

• I-2-Amino-6-mercaptopurine
• 6-HBN
• 6-Thioguanine