I-Melphalan

-Delile

• Ngaphambi kokuthatha i-melphalan,
• I-Melphalan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

IMelphalan ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho wethambo. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulimaza; ezinegazi noma ezimnyama, izitulo zokulinda; ukuhlanza kwegazi; noma ukugabha igazi noma okokusundu okufana nezindawo zekhofi.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo zaselebhu njalo ngaphambi nangesikhathi sokwelashwa kwakho ukubona ukuthi amaseli akho egazi ayathinteka yini yilo muthi.

IMelphalan ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha i-melphalan.

IMelphalan isetshenziselwa ukwelapha i-myeloma eminingi (uhlobo lomdlavuza womnkantsha wethambo). IMelphalan isetshenziselwa ukwelapha uhlobo oluthile lomdlavuza wesibeletho (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda). UMelphalan usesigabeni semithi ebizwa ngama-alkylating agents. Isebenza ngokumisa noma ukunciphisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

IMelphalan iza njengethebhulethi ezothathwa ngomlomo. Imvamisa iphuzwa esiswini esingenalutho kanye ngosuku. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza onawo. Thatha i-melphalan ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-melphalan njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho we-melphalan ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi oyitholayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Ungayeki ukuthatha i-melphalan ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

IMelphalan kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza webele. Kwesinye isikhathi kuyasetshenziswa ukwelapha i-amyloidosis (isifo lapho amaprotheni angajwayelekile akha khona ezicutshini nasezithweni zomzimba). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-melphalan,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-melphalan, noma imiphi eminye imishanguzo, noma ezinye izithako ezikumaphilisi e-melphalan. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-carmustine (BICNU, BCNU), i-cimetidine (i-Tagamet), i-cisplatin (i-Platinol AQ), i-cyclosporine (i-Sandimmune, i-Gengraf, i-Neoral), noma i-interferon alfa (i-Intron A, i-Infergen, i-Alferon N).
• Tshela udokotela wakho uma ngabe uke wathatha i-melphalan phambilini, kepha umdlavuza wakho awuphendulanga emithini. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-melphalan.
• tshela udokotela wakho uma ngabe uthole ukwelashwa ngemisebe noma enye i-chemotherapy muva nje noma uma uke waba nesifo sezinso noma wake waba naso.
• kufanele wazi ukuthi i-melphalan ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane futhi ingamisa okwesikhashana noma unomphela ukukhiqizwa kwesidoda emadodeni. I-Melphalan ingadala ukungazali (ubunzima bokukhulelwa); noma kunjalo, akufanele ucabange ukuthi awukwazi ukukhulelwa noma ukuthi awukwazi ukukhulelisa omunye umuntu. Abesifazane abakhulelwe noma abancelisayo kufanele batshele odokotela babo ngaphambi kokuba baqale ukusebenzisa lo muthi. Akufanele uhlele ukuba nezingane ngenkathi uthola i-chemotherapy noma isikhashana ngemuva kokwelashwa. (Khuluma nodokotela wakho ukuthola eminye imininingwane.) Sebenzisa indlela ethembekile yokulawula inzalo ukuvimbela ukukhulelwa. IMelphalan ingalimaza umbungu.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Melphalan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla noma isisindo
• izilonda emlonyeni nasemphinjeni
• isikhathi sokuya esikhathini (emantombazaneni nakwabesifazane)
• ubuhlungu obuhlangene, besisipha, noma beqolo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• isikhumba esiphaphathekile
• ukukhathala ngokweqile
• ukuquleka
• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• umchamo onombala omnyama
• izigaxa noma uquqaba olungavamile

I-Melphalan ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine esiqandisini kude nokukhanya.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuhlanza
• isifo sohudo
• izilonda emlonyeni nasemphinjeni
• okumnyama, okulindile, noma okokuchitha okunegazi
• ukuhlanza okunegazi noma okokuhlanza okubukeka njengezizathu zekhofi
• ukulimaza noma ukopha okungavamile
• umphimbo obuhlungu, ukukhwehlela, umkhuhlane, noma ezinye izimpawu zokutheleleka

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Alkeran^® Amathebulethi

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