Umlobi: Virginia Floyd
Usuku Lokudalwa: 10 Agasti 2021
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USMLE: Medical Video Lectures Pharmacology about Cytarabine by UsmleTeam
Ividiyo: USMLE: Medical Video Lectures Pharmacology about Cytarabine by UsmleTeam

-Delile

Umjovo weCytarabine kufanele unikezwe ngaphansi kweso lodokotela onolwazi lokunikeza imithi yamakhemikhali yokwelashwa komdlavuza.

I-cytarbine ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulimaza; indle emnyama neyokulinda; igazi elibomvu endle; ukuhlanza kwegazi; okokuhlanza okubukeka njengezizathu zekhofi.

I-Cytarabine isetshenziswa yodwa noma nezinye izidakamizwa ze-chemotherapy ukwelapha izinhlobo ezithile ze-leukemia (umdlavuza wamaseli amhlophe egazi), kufaka phakathi i-acute myeloid leukemia (AML), i-acute lymphocytic leukemia (ALL), kanye ne-leukemia engapheli (i-CML). I-Cytarabine nayo isetshenziswa yodwa noma nezinye izidakamizwa zamakhemikhali ukwelapha i-meningeal leukemia (umdlavuza kulwelwesi olumboza futhi luvikele umgogodla nobuchopho). I-Cytarabine isekilasini lemithi ebizwa ngama-antimetabolites. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.


I-Cytarabine iza njengempuphu exutshwe noketshezi ezofakwa ngaphakathi (emthanjeni), ngaphansi kwesikhumba (ngaphansi kwesikhumba), noma ngaphakathi (esikhaleni esigcwele uketshezi lomgogodla womgogodla) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Udokotela wakho uzokutshela ukuthi uzothola kangaki i-cytarabine. Isheduli incike esimweni onaso nokuthi umzimba wakho uphendula kanjani emithini.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

I-Cytarabine kwesinye isikhathi isetshenziselwa ukwelapha izinhlobo ezithile ze-non-Hodgkin's lymphoma (uhlobo lomdlavuza oluqala ngohlobo lwamaseli amhlophe egazi ngokuvamile alwa nokutheleleka). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-cytarabine,

  • Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cytarabine noma ezinye izithako zomjovo we-cytarabine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: digoxin (Lanoxin), flucytosine (Ancobon), noma i-gentamicin. Eminye imishanguzo ingaxhumana ne-cytarabine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
  • tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
  • tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe ngenkathi uthola umjovo we-cytarabine. Uma ukhulelwa ngenkathi uthola i-cytarabine, shayela udokotela wakho. I-Cytarabine ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.


I-Cytarabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • isicanucanu
  • ukuhlanza
  • isifo sohudo
  • ubuhlungu besisu
  • ukulahlekelwa isifiso sokudla
  • izilonda emlonyeni nasemphinjeni
  • ukulahleka kwezinwele
  • ubuhlungu bemisipha noma bamalunga
  • ukukhathala
  • amehlo abuhlungu noma abomvu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

  • ubuhlungu obuqhubekayo obuqala endaweni yesisu kepha bungasabalala baye emuva
  • ububomvu, ubuhlungu, ukuvuvukala, noma ukushisa endaweni lapho umjovo wanikezwa khona
  • isikhumba esiphaphathekile
  • ukuquleka
  • isiyezi
  • ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
  • ukuqubuka
  • isifuba
  • ukulunywa
  • ukuphefumula kanzima noma ukugwinya
  • ubuhlungu besifuba
  • ukuphuzi kwesikhumba noma kwamehlo
  • umchamo onombala omnyama noma ukuncipha kokuchama
  • ukuphelelwa umoya
  • ushintsho olungazelelwe noma ukulahleka kombono
  • isithuthwane
  • ukudideka
  • ukuba ndikindiki, ukushiswa, noma ukuncinza ezandleni, ezingalweni, ezinyaweni noma emilenzeni

I-Cytarabine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.


Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla.Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

  • UCytosar-U®
  • 1-beta-Arabinofuranosylcytosine
  • I-Arabinosylcytosine
  • I-Cytosine arabinoside
  • I-Ara-C
Kugcine ukubuyekezwa - 02/15/2012

-Kwaseviet

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UCatherine Hannan, MD

Okukhethekile Ekuhlinzweni Kwepla tikiUDkt. Catherine Hannan ungudokotela ohlinzayo wepula itiki. Uphothule eGeorgetown Univer ity Ho pital eWa hington DC. U ebenze e ibhedlela i-VA ku ukela ngo-2011 ...
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