Umlobi: Marcus Baldwin
Usuku Lokudalwa: 21 Ujuni 2021
Ukuvuselela Usuku: 16 Unovemba 2024
Anonim
Drug Development: Mechlorethamine (Valchor)
Ividiyo: Drug Development: Mechlorethamine (Valchor)

-Delile

Umjovo weMechlorethamine kufanele unikezwe ngaphansi kweso lodokotela onolwazi lokunikeza imishanguzo yamakhemikhali yokwelashwa komdlavuza.

IMechlorethamine ivame ukuhanjiswa emthanjeni kuphela. Kodwa-ke, ingahle ivuze izicubu eziseduze ezibangele ukucasuka okukhulu noma ukulimala. Udokotela wakho noma umhlengikazi uzoqapha indawo yakho yokuphatha ngale ndlela. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu, ukulunywa, ubomvu, ukuvuvukala, amabhamuza, noma izilonda endaweni lapho umjovo wafakwa khona.

IMechlorethamine isetshenziselwa ukwelapha iHodgkin's lymphoma (isifo sikaHodgkin) nezinhlobo ezithile ze-non-Hodgkin's lymphoma (izinhlobo zomdlavuza eziqala ngohlobo lwamaseli amhlophe egazi ngokuvamile alwa nokutheleleka); i-mycosis fungoides (uhlobo lomdlavuza wamasosha omzimba aqala ukuvela njengokuqubuka kwesikhumba); izinhlobo ezithile ze-leukemia (umdlavuza wamangqamuzana amhlophe egazi), kufaka phakathi i-lymphocytic leukemia engapheli (CLL) kanye ne-leukemia engapheli (i-CML); nomdlavuza wamaphaphu. IMechlorethamine nayo isetshenziselwa ukwelapha i-polycythemia vera (isifo lapho kwenziwa khona amangqamuzana egazi abomvu amaningi emnkantsheni wethambo). Ibuye isetshenziselwe ukuphatha ukwelashwa okulimazayo (isimo lapho uketshezi luqoqa emaphashini noma nxazonke zenhliziyo) okubangelwa izicubu zomdlavuza. IMechlorethamine isekilasini lemithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.


IMechlorethamine iza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Kungabuye kujovwe ngaphakathi (ngaphakathi kwesisu), ngaphakathi (ngaphakathi kwesifuba), noma nge-intrapericardially (emgqeni wenhliziyo). Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza noma isimo onaso.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-mechlorethamine,

  • Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-mechlorethamine, noma imiphi eminye imithi, noma iziphi izithako zomjovo we-mechlorethamine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
  • utshele udokotela wakho uma unesifo. Udokotela wakho angahle angafuni ukuthi uthole i-mechlorethamine.
  • Tshela udokotela wakho ukuthi uke wathola noma uzokwelashwa ngemisebe (x-ray) noma enye i-chemotherapy futhi uma uke waba nezimo ezithile zezempilo noma uke waba nazo.
  • kufanele wazi ukuthi i-mechlorethamine ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane, ingamisa ukukhiqizwa kwesidoda emadodeni, futhi ingadala nenzalo (kube nzima ukukhulelwa). Kodwa-ke, akufanele ucabange ukuthi wena noma umlingani wakho anikwazi ukukhulelwa. Tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma ukuncelisa. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola umjovo we-mechlorethamine. IMechlorethamine ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.


IMechlorethamine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • isicanucanu
  • ukuhlanza
  • ukulahlekelwa isifiso sokudla
  • isifo sohudo
  • ukukhathala okungajwayelekile noma ubuthakathaka
  • isiyezi
  • amalunga abuhlungu, avuvukile
  • kukhala ezindlebeni nobunzima bokuzwa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

  • umkhuhlane, amakhaza, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
  • ukopha okungajwayelekile noma ukulinyazwa
  • ezinegazi noma ezimnyama, izitulo zokulinda
  • ukuhlanza okunegazi
  • okokuhlanza okubukeka njengezizathu zekhofi
  • izinsini ezophayo
  • amachashazi amancane, ayindingilizi, abomvu noma ansomi esikhunjeni
  • isifuba
  • ukuqubuka
  • ukulunywa
  • ukuphefumula kanzima noma ukugwinya
  • ukuba ndikindiki noma ukuncinza ezandleni noma ezinyaweni
  • ukushaya kwenhliziyo okungajwayelekile

IMechlorethamine ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthola i-mechlorethamine.


IMechlorethamine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

  • umkhuhlane, amakhaza, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
  • ukopha okungajwayelekile noma ukulinyazwa
  • ezinegazi noma ezimnyama, izitulo zokulinda
  • ukuhlanza okunegazi
  • okokuhlanza okubukeka njengezizathu zekhofi

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-mechlorethamine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

  • I-Mustargen®
  • Isinaphi seNitrogen
Kugcine ukubuyekezwa - 08/15/2012

-Kwaseviet

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