I-Meclofenamate

-Delile

• Ngaphambi kokuthatha i-meclofenamate,
• I-Meclofenamate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha. Ungaphinde uthathe i-meclofenamate uze ukhulume nodokotela wakho.
• Izimpawu zokudlula ngokweqile zingafaka:

[Kuthunyelwe 10/15/2020]

Isithameli: Umthengi, Isiguli, Uchwepheshe Wezempilo, Ikhemisi

INKINGA: I-FDA iyisixwayiso sokuthi ukusetshenziswa kwama-NSAID cishe emasontweni angama-20 noma kamuva ekukhulelweni kungadala izinkinga zezinso ezingandile kodwa ezinzima enganeni engakazalwa. Lokhu kungaholela emazingeni aphansi e-amniotic fluid azungeze ingane kanye nezinkinga ezingenzeka.

Kuma-NSAID kadokotela, i-FDA idinga ushintsho emininingwaneni echazayo ukuchaza ubungozi bezinkinga zezinso ezinganeni ezingakazalwa okuholela kuketshezi oluphansi lwe-amniotic.

Ama-NSAID e-over-the-counter (OTC) ahloselwe ukusetshenziswa kubantu abadala, i-FDA izobuyekeza amalebula e-Drug Facts, atholakala ku: http://bit.ly/2Uadlbz. Lawa amalebula asevele exwayisa ngokugwema ukusebenzisa ama-NSAID phakathi nezinyanga ezi-3 ezedlule zokukhulelwa ngoba imishanguzo ingadala izinkinga enganeni engakazalwa noma ezinkingeni ngesikhathi sokubeletha. Amalebula e-Drug Facts asevele eluleka abesifazane abakhulelwe nabancelisayo ukuthi bacele uchwepheshe wezokunakekelwa kwempilo ngaphambi kokusebenzisa le mithi.

ISENDLALELO:

Ama-NSAID

• yisigaba semithi esitholakala ngemithi kadokotela ne-OTC. Yiminye yemithi esetshenziswa kakhulu yezinhlungu nomkhuhlane.
• asetshenziselwa ukwelapha izimo zezokwelapha ezifana nesifo samathambo, amajaqamba okuya esikhathini, ikhanda elibuhlungu, imikhuhlane nomkhuhlane.
• sebenza ngokuvimba ukukhiqizwa kwamakhemikhali athile emzimbeni adala ukuvuvukala.
• atholakala wedwa futhi ahlanganiswe neminye imithi. Izibonelo zama-NSAID afaka phakathi i-aspirin, ibuprofen, naproxen, diclofenac, ne-celecoxib.

Imiphumela emibi ejwayelekile yama-NSAID ifaka phakathi: ubuhlungu besisu, ukuqunjelwa, uhudo, igesi, isilungulela, isicanucanu, ukuhlanza, nesiyezi.

Ukuncoma:

Abathengi / Iziguli

• Uma ukhulelwe, ungasebenzisi ama-NSAID emasontweni angama-20 noma kamuva lapho ukhulelwe ngaphandle kwalapho weluleke ngokukhethekile ukuthi wenze njalo ngochwepheshe bezokunakekelwa kwezempilo ngoba le mithi ingadala izinkinga enganeni yakho engakazalwa.
• Imithi eminingi ye-OTC iqukethe ama-NSAID, kufaka phakathi lawo asetshenziselwa izinhlungu, imikhuhlane, umkhuhlane, nokuqwasha, ngakho-ke kubalulekile ukufunda amalebula e-Drug Facts, atholakala ku: http://bit.ly/2Uadlbz, ukuthola ukuthi ingabe Ama-NSAID.
• Khuluma nochwepheshe wezokunakekelwa kwezempilo noma wemithi uma unemibuzo noma ukukhathazeka mayelana nama-NSAID noma ukuthi imiphi imithi equkethe.
• Eminye imithi, efana ne-acetaminophen, iyatholakala ukwelapha ubuhlungu nomkhuhlane ngesikhathi sokukhulelwa. Khuluma nosokhemisi wakho noma uchwepheshe wezokunakekelwa kwempilo ngosizo lokunquma ukuthi yikuphi okungcono kakhulu.

Ochwepheshe Bokunakekelwa Kwezempilo

• I-FDA incoma ukuthi ochwepheshe bezokunakekelwa kwezempilo kufanele banciphise ukubekwa kwama-NSAID phakathi kwamaviki angama-20 kuye kwangama-30 okukhulelwa futhi bagweme ukuwabeka ngemuva kwamasonto angama-30 ekhulelwe. Uma ukwelashwa kwe-NSAID kunqunywa kudingekile, nciphisa ukusetshenziswa kumthamo osebenza ophansi kakhulu nesikhathi esifushane ngangokunokwenzeka. Cabanga ukuqapha kwe-ultrasound ye-amniotic fluid uma ukwelashwa kwe-NSAID kudlulela ngaphezu kwamahora angama-48 futhi uyeke i-NSAID uma kutholakala i-oligohydramnios. I-FDA ixwayisa ngokuthi ukusetshenziswa kwama-NSAID cishe ukukhulelwa amasonto angama-20 noma kamuva ekukhulelweni kungadala ukungasebenzi kahle kwezinso okuholela ku-oligohydramnios futhi, kwezinye izimo, ukukhubazeka kwezinso ezisanda kuzalwa.
• Le miphumela engemihle iyabonakala, ngokwesilinganiso, ngemuva kwezinsuku kuye emavikini ekwelashwa, yize i-oligohydramnios ibikwe kaningi ngokushesha ngemuva kwamahora angama-48 ngemuva kokuqala kwe-NSAID.
• I-Oligohydramnios ivame, kepha hhayi ngaso sonke isikhathi, ibuyiselwe ekuyekeni ukwelashwa.
• Izinkinga ze-oligohydramnios ezinde zingafaka izinkontileka zezitho kanye nokuvuthwa kwamaphaphu okulibazisekile. Kwezinye izimo zokumaketha ngemuva kokukhubazeka kwe-neonatal renal function, izinqubo zokuhlasela ezifana nokumpontshelwa igazi noma i-dialysis kwakudingeka.
• Uma ukwelashwa kwe-NSAID kubonakala kudingekile phakathi kwamaviki angama-20 kuya kwangama-30 okukhulelwa, ukunciphisa ukusetshenziswa komthamo osebenza ophansi kakhulu nesikhathi esifushane ngangokunokwenzeka. Njengoba kuchazwe njengamanje kumalebula we-NSAID, gwema ukunquma ama-NSAID emasontweni angama-30 futhi kamuva ekukhulelweni ngenxa yengozi eyengeziwe yokuvalwa ngaphambi kwesikhathi kwe-fetus ductus arteriosus.
• Izincomo ezingenhla azisebenzi kumthamo ophansi ongu-81 mg aspirin obekwe ezimweni ezithile lapho ukhulelwe.
• Cabanga ukuqapha kwe-ultrasound ye-amniotic fluid uma ukwelashwa kwe-NSAID kudlulela ngaphezu kwamahora angama-48. Yeka i-NSAID uma i-oligohydramnios ivela futhi ilandelela ngokuya ngomkhuba wokwelashwa.

Ukuthola eminye imininingwane vakashela iwebhusayithi ye-FDA ku: http://www.fda.gov/Safety/MedWatch/SafetyInformation naku-http: //www.fda.gov/Drugs/DrugSafety.

Abantu abathatha izidakamizwa ezingezona ukuvuvukala (ama-NSAID) (ngaphandle kwama-aspirin) afana ne-meclofenamate bangaba nengozi enkulu yokuhlaselwa yisifo senhliziyo noma isifo sohlangothi kunabantu abangayithathi le mithi. Le micimbi ingenzeka ngaphandle kwesixwayiso futhi ingadala ukufa. Le ngozi ingahle ibe phezulu kubantu abathatha ama-NSAID isikhathi eside. Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo senhliziyo, ehlaselwa yisifo senhliziyo, noma sohlangothi, uma ubhema, nokuthi ngabe uke waba ne-cholesterol ephezulu, umfutho wegazi ophakeme noma isifo sikashukela. Thola usizo lwezokwelapha oluphuthumayo ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: Ubuhlungu besifuba, ukuphefumula okuncane, ukuba buthakathaka engxenyeni eyodwa noma ohlangothini lomzimba, noma ukukhuluma okungaqinile.

Uma uzobe uhlolwa umthambo we-coronary bypass graft (CABG; uhlobo lokuhlinzwa kwenhliziyo), akufanele uthathe i-meclofenamate ngaphambi noma ngemuva kokuhlinzwa.

Ama-NSAID afana ne-meclofenamate angadala izilonda, ukuphuma kwegazi, noma izimbobo esiswini noma emathunjini. Lezi zinkinga zingakhula nganoma yisiphi isikhathi ngesikhathi sokwelashwa, zingenzeka ngaphandle kwezimpawu zokuxwayisa, futhi zingadala nokufa. Ingozi ingaba phezulu kubantu abathatha ama-NSAID isikhathi eside, sebekhulile ngeminyaka, benempilo ebuthaka, noma bephuza utshwala obuningi ngenkathi bethatha i-meclofenamate. Tshela udokotela wakho uma uthatha noma imuphi wale mithi elandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin); i-aspirin; amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); noma i-oral steroids efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (i-Medrol), ne-prednisone (i-Deltasone). Phinda utshele udokotela wakho uma uke waba nezilonda noma wopha esiswini noma emathunjini, noma ezinye izifo zokopha. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, yeka ukuthatha i-meclofenamate bese ufonela udokotela wakho: ubuhlungu besisu, isilungulela, uhlanza olunegazi noma olubukeka njengezindawo zekhofi, igazi elisesitokisini, noma izitulo ezimnyama nezokulinda.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoqapha izimpawu zakho ngokucophelela futhi mhlawumbe uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-meclofenamate. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ukuze udokotela wakho akwazi ukukubeka inani elifanele lemithi yokwelapha isimo sakho ngengozi ephansi kakhulu yemiphumela emibi kakhulu.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-meclofenamate futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) ukuthola uMhlahlandlela Wezokwelapha.

I-Meclofenamate isetshenziselwa ukudambisa izinhlungu, ubumnene, ukuvuvukala, nokuqina okubangelwa i-osteoarthritis (i-arthritis ebangelwa ukuwohloka kolwelwesi lwamajoyini) kanye nesifo samathambo (isifo samathambo esibangelwa ukuvuvukala kolwelwesi lwamajoyini). Ibuye isetshenziselwe ukukhulula ezinye izinhlobo zobuhlungu obumaphakathi kuya obulinganiselayo, kufaka phakathi ubuhlungu bokuya esikhathini (ubuhlungu obenzeka ngaphambi noma esikhathini sokuya esikhathini). Kungasetshenziselwa ukunciphisa ukopha kwabesifazane abanokulahleka kwegazi okuya esikhathini okunzima ngokweqile. IMeclofenamate isekilasini lemithi ebizwa ngama-NSAID. Isebenza ngokumisa ukukhiqizwa komzimba wento ebangela ubuhlungu, umkhuhlane nokuvuvukala.

IMeclofenamate iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa kathathu noma kane ngosuku ngesifo samathambo, kathathu ngosuku ekwehlisweni kwegazi okunzima kokuya esikhathini, noma njalo ngamahora amane kuya kwayisithupha njengoba kudingeka ngobuhlungu. I-Meclofenamate ingathathwa ngokudla noma ubisi ukuvimbela isicanucanu. Uma uthatha i-meclofenamate njalo, yithathe ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-meclofenamate njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma uthatha i-meclofenamate ukunciphisa ukopha okunzima kokuya esikhathini, ukuphuma kwakho kwegazi kufanele kwehle ngesikhathi sokwelashwa kwakho. Shayela udokotela wakho uma ukuphuma kwegazi kunganciphi noma uma ubona ukubonwa noma ukopha phakathi nesikhathi sokuya esikhathini.

Uma uthatha i-meclofenamate ukunciphisa izimpawu zesifo samathambo, izimpawu zakho zingaqala ukuthuthuka ezinsukwini ezimbalwa. Kungathatha amasonto amabili kuya kwamathathu noma ngaphezulu ukuthi uzwe inzuzo ephelele ye-meclofenamate.

I-Meclofenamate nayo isetshenziselwa ukwelapha i-ankylosing spondylitis (isifo samathambo esithinta kakhulu umgogodla), i-gouty arthritis (ubuhlungu bamalunga obubangelwa ukwakheka kwezinto ezithile emajoyintini), kanye ne-psoriatic arthritis (isifo samathambo esenzeka ngesifo sesikhumba esihlala isikhathi eside lokho kubangela ukukala nokuvuvukala). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ukwelapha isimo sakho.

Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-meclofenamate,

• Tshela udokotela wakho kanye nosokhemisi uma ungenwe i-meclofenamate, i-aspirin, noma amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) ne-naproxen (i-Aleve, iNaprosyn), noma imiphi eminye imithi, noma iziphi izithako ezingasebenzi kuma-capsule e-meclofenamate. Buza usokhemisi wakho ukuthola uhlu lwezithako ezingasebenzi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: ama-enzyme aguqula i-angiotensin (ACE) anjenge-benazepril (Lotensin), i-captopril (i-Capoten), i-enalapril (i-Vasotec), i-fosinopril (i-Monopril), i-lisinopril ( I-Prinivil, i-Zestril), i-moexipril (i-Univasc), i-perindopril (i-Aceon), i-quinapril (i-Accupril), i-ramipril (i-Altace), ne-trandolapril (i-Mavik); isisu (‘amaphilisi amanzi’); lithium (Eskalith, Lithobid); kanye ne-methotrexate (Rheumatrex). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe uke waba nanoma yimiphi yezimo okukhulunywe ngazo esigabeni ESIBALULEKILE SESEXWAYISO noma isifuba somoya, ikakhulukazi uma unamakhala agxishiwe kaningi noma agijimayo noma ama-polyp acinene (ukuvuvukala kolwelwesi lwekhala); ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi; noma isifo sesibindi noma sezinso.
• Tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, uhlela ukukhulelwa, noma uncelisa ibele. Uma ukhulelwa ngenkathi uthatha i-meclofenamate, shayela udokotela wakho.
• khuluma nodokotela wakho ngezingozi nezinzuzo zokuthatha i-meclofenamate uma uneminyaka engama-75 noma ngaphezulu. Ungathathi lo muthi isikhathi eside noma ngethamo eliphakeme kunokunconywa ngudokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-meclofenamate.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Meclofenamate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuqunjelwa
• igesi
• izilonda emlonyeni
• ikhanda
• kukhala ezindlebeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha. Ungaphinde uthathe i-meclofenamate uze ukhulume nodokotela wakho.

• ukungaboni kahle
• ukuzuza kwesisindo okungaqondakali
• imfiva
• amabhamuza
• ukuqubuka
• ukulunywa
• isifuba
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya
• ukuphuzi kwesikhumba noma kwamehlo
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ukungabi namandla
• isicanucanu
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• izimpawu ezinjengomkhuhlane
• isikhumba esiphaphathekile
• ukushaya kwenhliziyo okusheshayo
• kunamafu, umbala ogqamile, noma umchamo onegazi
• ukuhlungu obusemhlane
• ukuchama okunzima noma okubuhlungu

I-Meclofenamate ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukuziphatha okungenangqondo
• ukuyaluza
• isithuthwane
• ukuncipha kokuchama

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Meclodium^®¶
• Meclomen^®¶

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.