I-Niacin

-Delile

• I-Niacin isetshenziswa nezinguquko ekudleni (ukuvinjelwa kwe-cholesterol nokudla okunamafutha) ukunciphisa inani le-cholesterol (into efana namafutha) nezinye izinto ezinamafutha egazini lakho nokukhulisa inani le-lipoprotein ephakeme kakhulu (HDL; '' cholesterol enhle ''). I-Niacin ingasetshenziswa ezimeni eziningi kufaka phakathi okulandelayo:
• Ngaphambi kokuthatha i-niacin,
• I-Niacin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Niacin isetshenziswa nezinguquko ekudleni (ukuvinjelwa kwe-cholesterol nokudla okunamafutha) ukunciphisa inani le-cholesterol (into efana namafutha) nezinye izinto ezinamafutha egazini lakho nokukhulisa inani le-lipoprotein ephakeme kakhulu (HDL; '' cholesterol enhle ''). I-Niacin ingasetshenziswa ezimeni eziningi kufaka phakathi okulandelayo:

• eyedwa noma ihlanganiswe neminye imithi, efana ne-HMG-CoA inhibitors (ama-statins) noma izinhlaka ezibopha i-bile acid;
• ukunciphisa ubungozi bokuhlaselwa yisifo senhliziyo ezigulini ezine-cholesterol ephezulu ezihlaselwe yinhliziyo;
• ukuvimbela ukwanda kwe-atherosclerosis (i-cholesterol eningi kanye namafutha asezindongeni zemithambo yegazi) ezigulini ezine-cholesterol ephezulu nesifo semithambo yegazi;
• ukunciphisa inani lama-triglycerides (ezinye izinto ezinamafutha) egazini ezigulini ezinama-triglycerides aphezulu kakhulu asengozini yesifo se-pancreatic (izimo ezithinta amanyikwe, indlala ekhiqiza uketshezi lokudiliza ukudla namahomoni okulawula ushukela wegazi).

I-Niacin ibuye isetshenziselwe ukuvimbela nokwelapha i-pellagra (ukuntuleka kwe-niacin), isifo esibangelwa ukungadli ngokwanele nezinye izinkinga zezokwelapha. I-Niacin i-vitamin e-B eyinkimbinkimbi. Emithini yokwelashwa, i-niacin imithi yokwehlisa i-cholesterol.

Imiphumela yocwaningo lomtholampilo kubantu abanesifo senhliziyo namazinga e-cholesterol alawulwa kahle aqhathanisa abantu abathathe i-niacin ne-simvastatin nabantu abathathe i-simvastatin bodwa futhi bathola imiphumela efanayo kulawo maqembu amabili ngesilinganiso sokuhlaselwa yinhliziyo noma imivimbo. Ukuthatha i-niacin kanye ne-simvastatin noma i-lovastatin nakho akuboniswanga ukunciphisa ubungozi besifo senhliziyo noma sokufa uma kuqhathaniswa nokusetshenziswa kwe-niacin, simvastatin, noma i-lovastatin kuphela. Khuluma nodokotela wakho uma unemibuzo mayelana nezingozi nezinzuzo zokwelapha inani elinyukayo le-cholesterol egazini lakho nge-niacin neminye imithi.

INiacin iza njengethebhulethi kanye nethebhulethi ekhishwa isikhathi eside (esebenza isikhathi eside) ezothathwa ngomlomo. Ithebhulethi ejwayelekile ivame ukuthathwa izikhathi ezimbili noma ezintathu ngosuku nokudla, futhi ithebhulethi ekhishwa enwetshiwe ithathwa kanye ngosuku, ngesikhathi sokulala, ngemuva kokudla okuncane okunamafutha amancane. Landela izinkomba ezikulebuli kadokotela noma ilebula lephakheji ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-niacin njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi akhululiwe; ungawahlukanisi, ungawahlafune noma uwagxoze.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-niacin futhi akhuphule kancane umthamo wakho.

Qhubeka uthathe i-niacin noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-niacin ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-niacin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-niacin, noma imuphi omunye umuthi, noma iziphi izithako ezibhebheni ze-niacin. Buza usokhemisi wakho noma hlola imininingwane yomkhiqizi ngesiguli ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin); i-aspirin; i-insulin noma imithi yomlomo yesifo sikashukela; imithi yomfutho wegazi ophakeme; izithasiselo zokudla okunempilo noma eminye imikhiqizo equkethe i-niacin; noma eminye imithi yokwehlisa i-cholesterol noma i-triglycerides. Uma uthatha imithi ye-insulin noma yomlomo wesifo sikashukela, umthamo wakho ungadinga ukushintshwa ngoba i-niacin ingakhuphula inani likashukela egazini nasemchameni wakho.
• uma uthatha i-resin ebopha i-acid acid efana ne-colestipol (Colestid) noma i-cholestyramine (i-Questran), yithathe okungenani amahora amane kuya kwayisithupha ngaphambi noma ngemuva kwamahora ama-4 kuya kwayi-6 ngemuva kwe-niacin.
• utshele udokotela wakho uma uphuza utshwala obuningi nokuthi unesifo sikashukela noma wake waba naso yini; sifo; izilonda; ukungezwani komzimba nezinto ezithile; i-jaundice (ukuphuzi kwesikhumba noma kwamehlo); izinkinga zokopha; noma i-gallbladder, inhliziyo, izinso, noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-niacin, yeka ukuthatha i-niacin bese ushayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-niacin.
• buza udokotela wakho ngokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-niacin. Utshwala bungenza imiphumela emibi ye-niacin ibe yimbi kakhulu.
• kufanele wazi ukuthi i-niacin ibangela ukuqhuma (ububomvu, imfudumalo, ukulunywa, ukuncinza) kobuso, intamo, isifuba, noma emuva. Lo mphumela oseceleni uvame ukuphela ngemuva kokuthatha umuthi amasonto ambalwa. Gwema ukuphuza utshwala noma iziphuzo ezishisayo noma ukudla ukudla okubabayo ngesikhathi othatha i-niacin. Ukuthatha i-aspirin noma esinye isidakamizwa esilahla ukuvuvukala njenge-ibuprofen (Advil, Motrin) noma naproxen (Aleve, Naprosyn) imizuzu engama-30 ngaphambi kokuthi i-niacin inciphise ukuqhuma. Uma uthatha i-niacin ekhishwa isikhathi eside ngesikhathi sokulala, ukuqhuma kungenzeka kwenzeke ngenkathi ulele. Uma uvuka futhi uzizwa ushayekile, sukuma kancane, ikakhulukazi uma uzizwa unesiyezi noma uqulekile.

Yidla ukudla okunamafutha aphansi, okunamafutha amancane. Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Ungavakashela futhi iwebhusayithi ye-National Cholesterol Education Program (NCEP) ukuthola eminye imininingwane yokudla ku-http: //www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Uma uyeka ukuthatha i-niacin nganoma yisiphi ubude besikhathi, shayela udokotela wakho ngaphambi kokuba uqale ukuyithatha futhi.

I-Niacin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukukhwehlela okwandisiwe

Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isiyezi
• ukuquleka
• ukushaya kwenhliziyo okusheshayo
• isicanucanu
• ukuhlanza
• ukukhathala ngokweqile
• umchamo onombala omnyama
• indle enombala okhanyayo
• ukopha okungajwayelekile noma ukulinyazwa
• ukungabi namandla
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• Ubuhlungu bemisipha obungachazeki, ubumnene, noma ubuthakathaka

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zebhu ukuze ahlole impendulo yakho ku-niacin.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi uthatha i-niacin.

Sebenzisa kuphela uhlobo nohlobo lwe-niacin oluyalelwe ngudokotela wakho. Ungasebenzisi olunye uhlobo lwe-niacin noma ushintshe phakathi kwemikhiqizo ngaphandle kokukhuluma nodokotela wakho. Uma ushintshela kuhlobo oluhlukile noma uhlobo lwe-niacin, umthamo wakho ungadinga ukuguqulwa.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Niacor^®
• I-Niaspan^®
• UNicolar^®¶
• ISlo-Niacin^®

• I-Simcor^® (equkethe i-Niacin, Simvastatin)

• I-Nicotinic acid

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.