Umlobi: Marcus Baldwin
Usuku Lokudalwa: 18 Ujuni 2021
Ukuvuselela Usuku: 19 Unovemba 2024
Anonim
Co-trimoxazole and sudden death in patients receiving inhibitors of the renin-angiotensin system
Ividiyo: Co-trimoxazole and sudden death in patients receiving inhibitors of the renin-angiotensin system

-Delile

I-Co-trimoxazole isetshenziselwa ukwelapha izifo ezithile ezibangelwa amagciwane, njenge-pneumonia (ukutheleleka kwamaphaphu), i-bronchitis (ukutheleleka kwamashubhu aholela emaphashini), kanye nokutheleleka komgudu womchamo, izindlebe namathumbu. Iphinde isetshenziselwe ukwelapha ’uhudo lwabahambi. I-Co-trimoxazole iyinhlanganisela ye-trimethoprim ne-sulfamethoxazole futhi isesigabeni semithi ebizwa nge-sulfonamides. Isebenza ngokumisa ukukhula kwamagciwane. Ama-antibiotic ngeke abulale amagciwane angadala imikhuhlane, umkhuhlane, noma okunye ukutheleleka ngegciwane.

ICo-trimoxazole iza njengethebhulethi kanye nokumiswa (uketshezi) ukuthatha ngomlomo. Imvamisa iphuzwa kabili ngosuku kepha ingathathwa ize ifike kane ngosuku uma isetshenziselwa ukwelapha izifo ezithile zamaphaphu ezinzima. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-co-trimoxazole njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Kufanele uqale ukuzizwa ungcono phakathi nezinsuku ezimbalwa zokuqala zokwelashwa nge-co-trimoxazole. Uma izimpawu zakho zingathuthuki noma uma ziba zimbi kakhulu, shayela udokotela wakho.


Nyakazisa uketshezi kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo.

Thatha i-co-trimoxazole uze uqede incwadi kadokotela, noma ngabe uzizwa ungcono. Ungayeki ukuthatha i-co-trimoxazole ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukuthatha i-co-trimoxazole maduzane noma weqe imithamo, ukutheleleka kwakho kungenzeka kungalashwa ngokuphelele futhi amabhaktheriya angamelana nemithi elwa namagciwane.

Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-co-trimoxazole,

  • Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-co-trimoxazole, noma imuphi omunye umuthi, noma iziphi izithako kumaphilisi e-co-trimoxazole nokumiswa. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukusho okulandelayo: amantadine; i-angiotensin iguqula ama-enzyme inhibitors afana ne-benazepril (Lotensin), i-captopril (i-Capoten), i-enalapril (i-Vasotec), i-fosinopril (i-Monopril), i-lisinopril (i-Prinivil, i-Zestril), i-moexipril (i-Univasc), i-perindopril (i-Aceon) I-Altace), ne-trandolapril (Mavik); ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); i-cyclosporine (Gengraf, Neoral, Sandimmune); imishanguzo yomlomo wesifo sikashukela efana ne-glipizide (Glucotrol), i-glyburide (i-Diabeta, i-Glynase), i-metformin (i-Fortamet, i-Glucophage), i-pioglitazone (i-Actos), i-repaglinide (i-Prandin), i-rosiglitazone (i-Avandia); i-digoxin (i-Lanoxin); isisu (‘amaphilisi amanzi’); indomethacin (Indocin); leucovorin (Fusilev); imithi yokuquleka efana ne-phenytoin (iDilantin, Phenytek); i-memantine (Namenda); i-methotrexate (Trexall); i-pyrimethamine (iDaraprim). kanye ne-tricyclic antidepressants efana ne-amitriptyline (Elavil), i-amoxapine (Asendin), i-desipramine (i-Norpramin), i-doxepin (i-Adapin, i-Sinequan), i-imipramine (i-Tofranil), i-nortriptyline (i-Aventyl, i-Pamelor), i-protriptyline (i-Vivactil), i-Survipiline (i-Vivactil). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
  • Tshela udokotela wakho uma uke waba ne-thrombocytopenia (ngaphansi kwenani elijwayelekile lama-platelet) okubangelwa ukuthatha i-sulfonamides noma i-trimethoprim; i-megaloblastic anemia (amangqamuzana egazi abomvu angajwayelekile) adalwa ukushoda kwe-folate (amazinga aphansi egazi e-folic acid), i-phenylketonuria (i-PKU, isimo esizuzwe njengefa lapho kufanele kudliwe ukudla okhethekile ukuvimbela ukubola kwengqondo), noma isifo sesibindi noma sezinso. Udokotela wakho angakutshela ukuthi ungathathi i-co-trimoxazole. I-Co-trimoxazole akufanele isetshenziswe ezinganeni ezingaphansi kwezinyanga ezimbili ubudala.
  • utshele udokotela wakho uma ngabe uke waba nezifo ezinzima noma uke waba nazo? isifuba somoya; amazinga aphansi e-folic acid emzimbeni angabangelwa ukungondleki (awudli noma awukwazi ukugaya izakhi zomzimba ezidingekayo empilweni enhle); ukutheleleka ngegciwane lesandulela ngculaza (i-HIV); i-porphyria (isifo segazi esizuzwe njengefa esingadala izinkinga zesikhumba noma zesistimu yezinzwa); isifo segilo; noma ukushoda kwe-glucose-6-phosphate dehydrogenase (G-6-PD) (isifo segazi esizuzwe njengefa).
  • tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa.Uma ukhulelwa ngenkathi uthatha i-co-trimoxazole, shayela udokotela wakho ngokushesha. I-Co-trimoxazole ingalimaza umbungu.
  • hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, nesikhumba selanga. I-Co-trimoxazole ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.


Phuza uketshezi oluningi ngesikhathi sokwelashwa kwakho nge-co-trimoxazole.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Co-trimoxazole ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • isicanucanu
  • ukuhlanza
  • ukulahlekelwa isifiso sokudla

Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:

  • ukuqubuka
  • ukulunywa
  • Umphimbo obuhlungu
  • umkhuhlane noma amakhaza
  • Uhudo olunzima (indle enamanzi noma enegazi) engahle yenzeke noma ingenayo imfiva kanye neziqubu zesisu (kungenzeka izinyanga ezi-2 noma ngaphezulu ngemuva kokwelashwa kwakho)
  • ukuphelelwa umoya
  • ukukhwehlela
  • ukulimaza noma ukopha okungavamile
  • ukuphuzi kwesikhumba noma kwamehlo
  • ukuphaphatheka
  • ukuguqulwa kwesikhumba okubomvu noma okunsomi
  • ubuhlungu obuhlangene noma besisipha

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).


Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yakho ku-co-trimoxazole.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-co-trimoxazole.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Isidakamizwa sakho kungenzeka ukuthi asigcwaliseki. Uma usenezimpawu zokutheleleka ngemuva kokuqeda i-co-trimoxazole, shayela udokotela wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

  • IBactrim® (equkethe iSulfamethoxazole, Trimethoprim)
  • IBactrim® I-DS (iqukethe iSulfamethoxazole, Trimethoprim)
  • Septhemba® (equkethe iSulfamethoxazole, Trimethoprim)
  • Septhemba® I-DS (equkethe iSulfamethoxazole, Trimethoprim)
  • Septhemba® Ukumiswa (okuqukethe iSulfamethoxazole, Trimethoprim)
  • I-Sulfatrim® Ukumiswa (okuqukethe iSulfamethoxazole, Trimethoprim)

Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.

Kugcine ukubuyekezwa - 10/15/2017

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