Raloxifene
-Delile
- Ngaphambi kokuthatha i-raloxifene,
- I-Raloxifene ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- Izimpawu zokudlula ngokweqile zingafaka okulandelayo:
Ukuthatha i-raloxifene kungakhuphula ubungozi bokuthi uzoba negazi emilenzeni noma emaphashini. Tshela udokotela wakho uma ngabe uke waba negazi emilenzeni, emaphashini noma emehlweni. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-raloxifene. Yeka ukuthatha i-raloxifene bese ushayela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ubuhlungu bomlenze; umuzwa wokufudumala emlenzeni ongezansi; ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi; ubuhlungu besifuba kungazelelwe; ukuphelelwa umoya; ukukhwehlela igazi; noma ushintsho olungazelelwe kumbono, njengokulahleka kombono noma ukungaboni kahle.
Ukuhlala unganyakazi isikhathi eside kungandisa amathuba okuthi uzoba negazi. Udokotela wakho mhlawumbe uzokutshela ukuthi uyeke ukuthatha i-raloxifene okungenani ezinsukwini ezintathu ngaphambi kokuhlinzwa okuhleliwe futhi ungathathi umuthi uma udinga isikhathi esithe xaxa sokuphumula kombhede nganoma yisiphi isizathu. Uma uzohlinzwa, qiniseka ukuthi utshela udokotela wakho ukuthi uthatha i-raloxifene. Uma uhamba ngenkathi uthatha i-raloxifene, gwema ukuhlala unganyakazi (njengokuhlala endizeni noma emotweni) isikhathi eside phakathi nohambo lwakho.
Uma une-coronary artery disease (ukuqina kwemithambo eholela enhliziyweni engadala ubuhlungu besifuba noma ukuhlaselwa yinhliziyo) noma uma usengozini enkulu yokuthola isifo semithambo yegazi, ukuthatha i-raloxifene kungandisa amathuba okuthi uzoba nesifo esibi noma isifo sohlangothi esibulalayo. Tshela udokotela wakho ukuthi wake wahlaselwa yisifo sohlangothi noma ukushaywa unhlangothi okuncane, uma ubhema, nokuthi uke waba nomfutho wegazi ophakeme noma ukushaya kwenhliziyo okungafanele.
Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-raloxifene futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) noma iwebhusayithi yomkhiqizi ukuthola uMhlahlandlela Wezokwelapha.
I-Raloxifene isetshenziselwa ukuvimbela nokwelapha i-osteoporosis (isimo lapho amathambo eba mncane futhi abuthakathaka futhi aphuke kalula) e-postmenopausal (abesifazane abaye babhekana noshintsho lwempilo; ukuphela kwezikhathi zokuya esikhathini) abesifazane. I-Raloxifene ibuye isetshenziselwe ukunciphisa ubungozi bokuba nomdlavuza webele owesabekayo (umdlavuza webele osabalale ngaphandle kwemisele yobisi noma ama-lobules ezicutshini zesifuba ezungezile) kwabesifazane abasesemva kokuya esikhathini abasengozini enkulu yokuthola lolu hlobo lomdlavuza noma abane-osteoporosis . I-Raloxifene ayikwazi ukusetshenziselwa ukwelapha umdlavuza webele noma ukuhlasela umdlavuza webele ongafuneki ukuthi ubuyele kubantu besifazane asebeke baba nalesi simo. I-Raloxifene nayo ayinakusetshenziswa ukunciphisa ubungozi bokuba nomdlavuza webele ongahlaseli. URaloxifene kufanele hhayi isetshenziswe kwabesifazane abangakabi nakho ukuya esikhathini. I-Raloxifene isekilasini lemithi ebizwa nge-selective estrogen receptor modulators (SERMs). I-Raloxifene ivimbela futhi ilaphe i-osteoporosis ngokulingisa imiphumela ye-estrogen (ihomoni yabesifazane ekhiqizwa ngumzimba) ukukhulisa ukuqina kwethambo. I-Raloxifene inciphisa ubungozi bokuhlaselwa umdlavuza webele ngokuhlasela ngokuvimba imiphumela ye-estrogen ezicutshini zamabele. Lokhu kungamisa ukukhula kwezimila ezidinga ukuthi i-estrogen ikhule.
I-Raloxifene iza njengethebhulethi ukuthatha ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-raloxifene ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-raloxifene njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.
Qhubeka nokusebenzisa i-raloxifene noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-raloxifene ngaphandle kokukhuluma nodokotela wakho.
Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.
Ngaphambi kokuthatha i-raloxifene,
- Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-raloxifene, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-raloxifene. Buza usokhemisi wakho ukuthola uhlu lwezithako.
- Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants ('ama-thinner egazi') afana ne-warfarin (Coumadin, Jantoven), cholestyramine (Prevalite), colestipol (Colestid), diazepam (Valium), diazoxide (Proglycem), imithi equkethe i-estrogen enjalo njenge-hormone replacement therapy (ERT noma i-HRT), ne-lidocaine (Akten, Lidoderm, Xylocaine). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
- utshele udokotela wakho uma unanoma yiluphi uhlobo lomdlavuza nokuthi ngabe uke waba nezigaxa zesifuba noma umdlavuza webele noma wake waba nazo yini; ukwehluleka kwenhliziyo; isifo sezinso; noma isifo sesibindi. Uma ngabe uke wathatha i-estrogen, tshela udokotela wakho uma ama-triglycerides akho enyukile ngesikhathi sokwelashwa kwakho.
- utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Ungakhulelwa ngenkathi uthatha i-raloxifene. Uma ukhulelwa ngenkathi uthatha i-raloxifene, shayela udokotela wakho ngokushesha. I-Raloxifene ingalimaza umbungu.
- kufanele wazi ukuthi i-raloxifene ayitholakalanga ukuthi ibangela ukuphuma kwegazi noma ukuya esikhathini noma ukwandisa ingozi yomdlavuza wolwelwesi lwesibeletho. Tshela udokotela wakho uma uqala ukuphuma kwegazi noma ukubona. Udokotela wakho uzodinga ukukuhlola noma oda izivivinyo ukuthola imbangela yokopha.
- kufanele wazi ukuthi yize i-raloxifene inciphisa ithuba lokuthi uzoba nomdlavuza webele ongenayo, kusesengcupheni yokuthi uzoba nalesi simo. Usazodinga izivivinyo zebele ezihleliwe kanye nama-mammograms ngaphambi kokuba uqale ukuthatha i-raloxifene nangesikhathi sokwelashwa kwakho nge-raloxifene. Shayela udokotela wakho uma ubona ubumnene, ukukhuliswa, izigaxa, noma olunye uguquko emabeleni akho.
- uma uthatha i-raloxifene ukwelapha i-osteoporosis, khuluma nodokotela wakho ngezinye izinto ongazenza ukuvimbela i-osteoporosis ekuthuthukiseni noma ekubandeni. Udokotela wakho mhlawumbe uzokutshela ukuthi ugweme ukubhema nokuphuza utshwala obuningi futhi ulandele uhlelo olujwayelekile lokuzivocavoca umzimba.
Kufanele udle futhi uphuze ukudla okuningi neziphuzo ezicebile nge-calcium novithamini D ngenkathi uthatha i-raloxifene. Udokotela wakho uzokutshela ukuthi yikuphi ukudla neziphuzo okungumthombo omuhle walezi zinongo nokuthi zingaki izinsizakalo ozidingayo usuku ngalunye. Uma ukuthola kunzima ukudla okwanele kwalokhu kudla noma uma unesimo esenza kube nzima emzimbeni wakho ukuthola umsoco owudlayo, tshela udokotela wakho. Uma kunjalo, udokotela wakho angakunikeza noma ancome ukuthi kufakwe isengezo.
Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi sedosi yakho elandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.
I-Raloxifene ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- ukushisa okushisayo (okuvame kakhulu ezinyangeni eziyisithupha zokuqala zokwelashwa kwe-raloxifene)
- amajaqamba omlenze
- ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
- umkhuhlane onjenge-syndrome
- ubuhlungu obuhlangene
- ukujuluka
- ubunzima bokulala noma ukulala
Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi izimpawu ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha.
I-Raloxifene ingadala eminye imiphumela emibi. Shayela udokotela wakho uma uhlangabezana nezimpawu ezingavamile ngenkathi uthatha lo muthi.
Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).
Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).
Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula.Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org
Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.
Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.
Izimpawu zokudlula ngokweqile zingafaka okulandelayo:
- amajaqamba omlenze
- isiyezi
- ukulahleka kokuxhumanisa
- ukuhlanza
- ukuqubuka
- isifo sohudo
- ukuthuthumela
- ukuqhuma
Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri.
Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.
Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.
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