I-Acute vs. Hepatitis C Engapheli: Ukuqonda Izinketho Zakho Zokwelapha

-Delile

• Ukwelashwa kwe-hepatitis C enamandla
• Ukwelashwa kwe-hepatitis C engapheli
• Ukufakelwa kwesibindi
• Khuluma nodokotela wakho

IHepatitis C yisifo esithinta isibindi. Ukuhlala ne-hepatitis C isikhathi eside kungalimaza isibindi sakho kuze kube seqophelweni lapho singasebenzi kahle khona. Ukwelashwa kusenesikhathi kungasiza ukuvikela isibindi sakho futhi kulondoloze ikhwalithi yempilo yakho.

Odokotela bahlukanisa i-hepatitis C ibe yizinhlobo ezimbili ngokuya ngesimo osibe naso isikhathi esingakanani:

• I-hepatitis C enamandla yisigaba sokuqala lapho uke waba ne-hepatitis isikhathi esingaphansi kwezinyanga eziyisithupha.
• I-hepatitis C engalapheki uhlobo lwesikhathi eside, okusho ukuthi ubunesimo okungenani izinyanga eziyisithupha. Kuya kubantu abanesifo sokusha kwesibindi kohlobo C ekugcineni bazokwakha lesi sifo esingelapheki.

Udokotela wakho uzoncoma ukwelashwa okususelwa kuhlobo lwe-hepatitis C onayo. Ukuqonda izinketho zakho zokwelashwa kuzokusiza wenze izinqumo ezinolwazi.

Ukwelashwa kwe-hepatitis C enamandla

Uma une-hepatitis C ebucayi, awudingi ukuyelapha ngokushesha. Kubantu abanalesi sifo, kuzozicacela ngaphandle kokwelashwa.

Uzodinga ukuqashwa, noma kunjalo. Udokotela wakho uzokunikeza ukuhlolwa kwegazi kwe-HCV RNA njalo emavikini amane kuya kwayisishiyagalombili cishe izinyanga eziyisithupha. Lokhu kuhlolwa kukhombisa ukuthi lingakanani igciwane le-hepatitis C (HCV) elisegazini lakho.

Ngalesi sikhathi, usengadlulisela leli gciwane kwabanye ngokuxhumana kwegazi negazi. Gwema ukwabelana noma ukusebenzisa kabusha izinaliti. Isibonelo, lokhu kufaka phakathi ukuthola i-tattoo noma ukubhoboza endaweni engalawulwa, noma ukujova izidakamizwa. Ngesikhathi sokuya ocansini, sebenzisa ikhondomu noma enye indlela yokuvimbela ukubeletha ukugwema ukudlulisela igciwane kwabanye.

Uma igciwane liphela ngezinyanga eziyisithupha, awudingi ukwelashwa. Kodwa kubalulekile ukuthatha izinyathelo zokugwema ukuthola igciwane futhi esikhathini esizayo.

Ukwelashwa kwe-hepatitis C engapheli

Ukuhlolwa kwegazi okuhle kwe-HCV RNA ngemuva kwezinyanga eziyisithupha kusho ukuthi unesifo esingalapheki se-hepatitis C. Uzodinga ukwelashwa ukuvimbela igciwane ekulimaleni kwesibindi sakho.

Ukwelashwa okuyinhloko kusetshenziswa imishanguzo yokulwa namagciwane ukususa igciwane egazini lakho. Imithi emisha elwa namagciwane ingaphulukisa ngaphezu kwabantu abane-hepatitis C. engapheli.

Udokotela wakho uzokhetha umuthi olwa namagciwane noma inhlanganisela yezidakamizwa ngokuya ngenani lokulimala kwesibindi onakho, yiziphi izindlela zokwelashwa obukade unazo esikhathini esidlule, nokuthi unaluphi uhlobo lwe-hepatitis C onalo. Kunezakhi zofuzo eziyisithupha. Uhlobo ngalunye luphendula emithini ethile.

Imithi elwa namagciwane evunyelwe yi-FDA ukwelapha isifo sokusha kwesibindi kohlobo C ihlanganisa:

• i-daclatasvir / sofosbuvir (iDaklinza) - izinhlobo 1 no-3
• i-elbasvir / grazoprevir (iZepatier) - izinhlobo 1 no-4
• glecaprevir / pibrentasvir (Mavyret) - izinhlobo 1, 2, 5, 6
• ledipasvir / sofosburir (Harvoni) - izinhlobo 1, 4, 5, 6
• ombitasvir / paritaprevir / ritonavir (Technivie) - uhlobo 4
• I-ombitasvir / paritaprevir / ritonavir ne-dasabuvir (i-Viekira Pak) - i-genotypes 1a, 1b
• simeprevir (Olysio) - uhlobo 1
• sofosbuvir / velpatasvir (Epclusa) - wonke ama-genotypes
• i-sofosbuvir (Sovaldi) - wonke ama-genotypes
• sofosbuvir / velpatasvir / voxilaprevir (Vosevi) - wonke ama-genotypes

I-Peginterferon alfa-2a (Pegasys), i-peginterferon alfa-2b (Pegintron), ne-ribavirin (i-Copegus, i-Rebetol, i-Ribasphere) kwakuyindlela yokwelapha ejwayelekile ye-hepatitis C. engapheli C. Kodwa-ke, bathatha isikhathi eside ukusebenza futhi kaningi babengasebenzi welapha igciwane. Ziphinde zabangela imiphumela emibi efana nomkhuhlane, ukugodola, ukulahlekelwa isifiso sokudla, nomphimbo obuhlungu.

Namuhla, i-peginterferon alfa ne-ribavirin zisetshenziswa kancane ngoba imishanguzo emisha elwa namagciwane iyasebenza kakhulu futhi idala imiphumela emibi embalwa. Kodwa ukuhlanganiswa kwe-peginterferon alfa, i-ribavirin, ne-sofosbuvir kuseyindlela ejwayelekile yokwelashwa kwabantu abane-genatitis 1 no-4 ye-hepatitis C.

Uzothatha imishanguzo ye-hepatitis amasonto ayi-8 kuye kwayi-12. Ngesikhathi sokwelashwa, udokotela wakho uzokunika ukuhlolwa kwegazi ngezikhathi ezithile ukukala inani legciwane le-hepatitis C elisele egazini lakho.

Umgomo ukungabi nalo umkhondo wegciwane egazini lakho okungenani emasontweni ayi-12 uqeda ukwelashwa. Lokhu kubizwa ngokuthi yi-virologic response, noma i-SVR. Kusho ukuthi ukwelashwa kwakho kube yimpumelelo.

Uma umuthi wokuqala owuzamayo ungasebenzi, udokotela wakho angakunika umuthi ohlukile ongaba nemiphumela engcono.

Ukufakelwa kwesibindi

IHepatitis C ilimaza isibazi. Uma ngabe uphile nalesi sifo iminyaka eminingi, isibindi sakho singalimala size singabe sisasebenza. Ngaleso sikhathi, udokotela wakho angancoma ukufakelwa kwesibindi.

Ukufakelwa kwesibindi kususa isibindi sakho esidala bese sikufaka okusha, okunempilo. Imvamisa isibindi sivela kumnikeli oshonile, kepha ukufakelwa kwabaxhasi okuphilayo nakho kungenzeka.

Ukuthola isibindi esisha kuzokusiza uzizwe ungcono, kepha ngeke kuselaphe isifo sakho sokusha kwesibindi kohlobo C. Ukuze usebenzele ukwelapha igciwane nokufeza i-SVR, kusazodingeka uthathe umuthi wamagciwane ofana nohlobo lwesifo sakho.

Khuluma nodokotela wakho

Namuhla, ukwelashwa okusha kwama-antiviral kuyasiza ekwelapheni abantu abaningi abane-hepatitis C kunaseminyakeni edlule. Uma une-hepatitis C noma ungaba sengozini yako, qiniseka ukubona udokotela wakho. Bangakuhlolela igciwane futhi banqume ukuthi hlobo luni lwe-hepatitis C ongahle ube nalo. Uma udinga ukwelashwa, udokotela wakho angakusiza ukuthi wakhe uhlelo lokwelashwa lokulawula i-hepatitis C futhi usebenzele ukwelashwa.