I-Adrenocorticotropic Hormone (ACTH)

-Delile

• Kuyini ukuhlolwa kwe-hormone ye-adrenocorticotropic (ACTH)?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-ACTH?
• Kwenzekani ngesikhathi sokuhlolwa kwe-ACTH?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-ACTH?
• Izinkomba

Kuyini ukuhlolwa kwe-hormone ye-adrenocorticotropic (ACTH)?

Lokhu kuhlolwa kukala izinga le-adrenocorticotropic hormone (ACTH) egazini. I-ACTH iyi-hormone eyenziwe yindlala ye-pituitary, indlala encane engezansi kobuchopho. I-ACTH ilawula ukukhiqizwa kwenye i-hormone ebizwa nge-cortisol. ICortisol yenziwa yizindlala ze-adrenal, izindlala ezimbili ezincane ezingaphezulu kwezinso. ICortisol ibamba iqhaza elibalulekile ekusizeni:

• Phendula ekucindezelekeni
• Yilwa nokutheleleka
• Lawula ushukela wegazi
• Gcina umfutho wegazi
• Lawula imetabolism, inqubo yokuthi umzimba wakho usebenzisa kanjani ukudla namandla

I-cortisol eningi kakhulu noma encane kakhulu ingadala izinkinga ezinkulu zempilo.

Amanye amagama: I-Adrenocorticotropic hormone test test, i-corticotropin

Kusetshenziselwa ini?

Ukuhlolwa kwe-ACTH kuvame ukwenziwa kanye nokuhlolwa kwe-cortisol ukuxilonga ukuphazamiseka kwezindlala ze-pituitary noma ze-adrenal. Lokhu kufaka phakathi:

• ICushing’s syndrome, ukuphazamiseka lapho i-adrenal gland yenza i-cortisol eningi kakhulu. Kungahle kubangelwe yisimila endlaleni ye-pituitary noma ukusetshenziswa kwemithi ye-steroid. Ama-steroid asetshenziselwa ukwelapha ukuvuvukala, kepha angaba nemiphumela engemihle ethinta amazinga e-cortisol.
• Isifo sikaCushing, uhlobo lwe-Cushing’s syndrome. Kulesi sifo, i-pituitary gland yenza i-ACTH eningi kakhulu. Imvamisa kubangelwa isimila esingenasifo somdlavuza we-pituitary.
• Isifo i-Addison, isimo lapho i-adrenal gland ingenzi i-cortisol eyanele.
• I-Hypopituitarism, ukuphazamiseka lapho indlala yamapayipi ingeneli ngokwanele amanye noma wonke amahomoni ayo.

Kungani ngidinga ukuhlolwa kwe-ACTH?

Ungadinga lokhu kuhlolwa uma unezimpawu ze-cortisol eningi kakhulu noma encane kakhulu.

Izimpawu ze-cortisol eningi kakhulu zifaka:

• Ukuzuza kwesisindo
• Ukwakheka kwamafutha emahlombe
• Olayini abomvana noma abansomi (imigqa) esiswini, emathangeni, kanye / noma emabeleni
• Isikhumba esilimaza kalula
• Izinwele zomzimba ezandisiwe
• Ubuthakathaka bemisipha
• Ukukhathala
• Izinduna

Izimpawu ze-cortisol encane kakhulu zifaka:

• Ukwehla kwesisindo
• Isicanucanu nokuhlanza
• Uhudo
• Ubuhlungu besisu
• Isiyezi
• Ukwenza mnyama kwesikhumba
• Ukulangazelela usawoti
• Ukukhathala

Ungase futhi udinga lolu vivinyo uma unezimpawu ze-hypopituitarism. Izimpawu zizohluka ngokuya ngobukhulu besifo, kepha zingafaka okulandelayo:

• Ukuphelelwa isifiso sokudla
• Isikhathi esingajwayelekile sokuya esikhathini nokungabi nenzalo kwabesifazane
• Ukulahleka kwezinwele zomzimba nobuso emadodeni
• Ukuya ocansini okuphansi kwabesilisa nabesifazane
• Ukuzwela emakhazeni
• Ukuchama kaningi kunokujwayelekile
• Ukukhathala

Kwenzekani ngesikhathi sokuhlolwa kwe-ACTH?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Ungadinga ukuzila ukudla (ungadli noma uphuze) ubusuku bonke ngaphambi kokuhlolwa. Ukuhlolwa kuvame ukwenziwa ekuseni kakhulu ngoba amazinga e-cortisol ayashintsha usuku lonke.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Imiphumela yokuhlolwa kwe-ACTH ivame ukuqhathaniswa nemiphumela yokuhlolwa kwe-cortisol futhi ingakhombisa okukodwa kokulandelayo:

• Amazinga aphezulu e-ACTH namazinga aphezulu e-cortisol: Lokhu kungasho isifo sikaCushing.
• Izinga eliphansi le-ACTH namazinga aphezulu e-cortisol: Lokhu kungasho i-Cushing's syndrome noma isimila sendlala ye-adrenal.
• Amazinga aphezulu e-ACTH namazinga aphansi e-cortisol: Lokhu kungasho isifo se-Addison.
• Ama-ACTH aphansi namazinga aphansi e-cortisol. Lokhu kungasho hypopituitarism.

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-ACTH?

Isivivinyo esibizwa ngokuthi yi-ACTH test stimulation test kwesinye isikhathi senziwa esikhundleni sokuhlolwa kwe-ACTH ukuthola isifo se-Addison kanye ne-hypopituitarism. Ukuhlolwa kokukhuthaza i-ACTH ukuhlolwa kwegazi okukala amazinga e-cortisol ngaphambi nangemva kokuthola umjovo we-ACTH.

Izinkomba

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Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.