Umlobi: Marcus Baldwin
Usuku Lokudalwa: 19 Ujuni 2021
Ukuvuselela Usuku: 1 Ujulayi 2024
Anonim
Ukuhlolwa kwe-Alpha-Fetoprotein (AFP) - Umuthi
Ukuhlolwa kwe-Alpha-Fetoprotein (AFP) - Umuthi

-Delile

Kuyini ukuhlolwa kwe-alpha-fetoprotein (AFP)?

I-Alpha-fetoprotein (AFP) yiprotheni ekhiqizwa esibindini somntwana okhulayo. Ngesikhathi sokukhula kwengane, enye i-AFP idlula nge-placenta iye egazini likanina. Ukuhlolwa kwe-AFP kukala izinga le-AFP kwabesifazane abakhulelwe phakathi ne-trimester yesibili yokukhulelwa. I-AFP eningi kakhulu noma encane egazini likamama kungaba uphawu lokukhubazeka kokuzalwa noma esinye isimo. Lokhu kufaka phakathi:

  • I-neural tube defect, isimo esibi esibangela ukukhula okungavamile kwengqondo yengane ekhulayo kanye / noma umgogodla
  • I-Down syndrome, isifo sofuzo esidala ukukhubazeka kwengqondo nokubambezeleka kwentuthuko
  • Amawele noma ukuzalwa okuningi, ngoba ingane engaphezu kweyodwa ikhiqiza i-AFP
  • Ukubalwa okungalungile kwedethi yamanqamu, ngoba amazinga e-AFP ayashintsha ngesikhathi sokukhulelwa

Amanye amagama: AFP Maternal; I-Maternal Serum AFP; Isikrini se-msAFP

Kusetshenziselwa ini?

Ukuhlolwa kwegazi le-AFP kusetshenziselwa ukuhlola umbungu okhulayo engcupheni yokukhubazeka kokuzalwa kanye nokuphazamiseka kofuzo, njengokukhubazeka kwe-neural tube noma i-Down syndrome.


Kungani ngidinga ukuhlolwa kwe-AFP?

I-American Pregnancy Association ithi bonke abesifazane abakhulelwe kufanele banikezwe ukuhlolwa kwe-AFP esikhathini esithile phakathi kwesonto le-15 kanye nelama-20 lokukhulelwa. Ukuhlolwa kunganconywa ikakhulukazi uma:

  • Yiba nomlando womndeni wokukhubazeka kokuzalwa
  • Uneminyaka engama-35 noma ngaphezulu
  • Unesifo sikashukela

Kwenzekani ngesikhathi sokuhlolwa kwe-AFP?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi ukulungiswa okukhethekile kokuhlolwa kwe-AFP.

Ingabe zikhona izingozi esivivinyweni?

Kunobungozi obuncane kakhulu kuwe noma enganeni yakho ngokuhlolwa kwegazi le-AFP. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha. Olunye uvivinyo olubizwa nge-amniocentesis lunikeza ukuxilongwa okunembile kwe-Down syndrome nezinye izinkinga zokuzalwa, kodwa ukuhlolwa kunengozi encane yokubangela ukukhulelwa kwesisu.


Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa ukuphakama kunamazinga ajwayelekile e-AFP, kungasho ukuthi ingane yakho inesici se-neural tube esinjenge-spina bifida, isimo lapho amathambo omgogodla engavali eduze komgogodla, noma i-anencephaly, ubuchopho abukhuli kahle.

Uma imiphumela yakho ikhombisa ukuthi ingaphansi kwamazinga ajwayelekile e-AFP, kungasho ukuthi ingane yakho inenkinga yezofuzo efana ne-Down syndrome, isimo esidala izinkinga zengqondo nezentuthuko.

Uma amazinga akho e-AFP angajwayelekile, akusho ukuthi kunenkinga enganeni yakho. Kungasho ukuthi unezingane ezingaphezu kweyodwa noma ukuthi usuku lwakho olufanele alulungile. Ungase futhi uthole umphumela ongemuhle. Lokho kusho ukuthi imiphumela yakho ikhombisa inkinga, kepha ingane yakho iphilile. Uma imiphumela yakho ikhombisa izinga eliphakeme noma eliphansi kunelejwayelekile le-AFP, cishe uzothola izivivinyo eziningi zokusiza ukuxilonga.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-AFP?

Ukuhlolwa kwe-AFP kuvame ukuba yingxenye yochungechunge lwezivivinyo zokubeletha ezibizwa ngokuthi ukumaka okuningi noma ukuhlolwa kwesikrini kathathu. Ngaphezu kwe-AFP, ukuhlolwa kwesikrini okuphindwe kathathu kufaka phakathi ukuhlolwa kwe-hCG, i-hormone ekhiqizwa yi-placenta, ne-estriol, uhlobo lwe-estrogen olwenziwe umbungu. Lezi zivivinyo zingasiza ukuxilonga i-Down syndrome nezinye izifo zofuzo.


Uma usengozini enkulu yokuba nengane enokukhubazeka okuthile kokuzalwa, umhlinzeki wakho futhi angancoma ukuhlolwa okusha okubizwa nge-DNA engenaseli (cfDNA). Lokhu ukuhlolwa kwegazi okunganikezwa ngaphambi kwe-10th isonto lokukhulelwa. Ingakhombisa ingakhombisa ukuthi ngabe ingane yakho inethuba eliphakeme lokuba ne-Down syndrome noma ezinye izifo zofuzo.

Izinkomba

  1. Inhlangano yaseMelika Yokukhulelwa [i-Intanethi]. I-Irving (TX): Inhlangano Yokukhulelwa yaseMelika; c2017. Ukuhlolwa kwe-Maternal Serum Alpha-Fetoprotein (MSAFP) [kubuyekezwe ngo-2016 Sep 2; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein-screening
  2. Inhlangano yaseMelika Yokukhulelwa [i-Intanethi]. I-Irving (TX): Inhlangano Yokukhulelwa yaseMelika; c2017. Ukuhlolwa kwesikrini esintathu [kubuyekezwe ngo-2016 Sep 2; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
  3. Amathuna JC, Miller KE, Abathengisi AD. Ukuhlolwa Kwe-Maternal Serum Triple Analyte Ekukhulelweni. Ngingudokotela We-Fam [Inthanethi]. I-2002 Mar 1 [icashunwe ngo-2017 Jun 5]; 65 (5): 915–921. Kutholakala kusuka: https://www.aafp.org/afp/2002/0301/p915.html
  4. UJohn Hopkins Medicine [Inthanethi]. UJohn Hopkins Medicine; ILabhulali Yezempilo: Ukuhlolwa Okuvamile Ngesikhathi Sokukhulelwa [okushiwo ngo-2017 Juni 5]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/pregnancy_and_childbirth/common_tests_during_pregnancy_85,p01241
  5. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2019. Ukuhlolwa Kwama-Serum Womama, I-Trimester Yesibili; [kubuyekezwe i-2019 Meyi 6; icashunwe ngo-2019 Jun 4]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/maternal-serum-screening-second-trimester
  6. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. I-American Association for Clinical Chemistry; c2001–2017. Uhla lwamagama: I-Spina Bifida [icashunwe ngo-2017 Juni 5]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/glossary/spina-bifida
  7. Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co Inc .; c2017. Ukuhlola Ukuxilongwa Kwangaphambi Kokubeletha [kubuyekezwe ngo-2017 Juni; icashunwe ngo-2019 Juni 4]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://www.merckmanuals.com/home/women-s-health-issues/detection-of-genetic-disorders/prenatal-diagnostic-testing
  8. Isikhungo Sikazwelonke Sokuthuthukisa Isayensi Yokuhumusha / Isikhungo Semininingwane Yezofuzo kanye Nezifo Ezingajwayelekile [i-Intanethi]. IGaithersburg (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Amaphutha we-Neural Tube [abuyekezwe ngo-2013 Nov 6; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
  9. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ziyini Izingozi Zokuhlolwa Kwegazi? [kubuyekezwe 2012 Jan 6; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-5]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
  10. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ongakulindela Nezivivinyo Zegazi [kubuyekezwe ngo-2012 Jan 6; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
  11. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: I-Alpha-fetoprotein (AFP) [icashunwe ngo-2017 Juni 5]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid;=P02426
  12. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: I-Alpha-fetoprotein (Igazi) [icashunwe ngo-2017 Juni 5]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alpha_fetoprotein_maternal_blood
  13. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2017. Imininingwane Yezempilo: I-Alpha-Fetoprotein (AFP) eseGazini [ibuyekezwe ngo-2016 Juni 30; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-5]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
  14. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2017. Imininingwane Yezempilo: Ukuhlolwa Kathathu noma Kuka-Quad Kokutholwa Kokuzalwa [kubuyekezwe ngo-2016 Juni 30; kukhonjiwe ngo-2017 Juni 5]; [cishe izikrini ezi-5]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-screening-test/ta7038.html#ta7038-sec

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.

Ngokumangazayo

I-Pseudomembranous colitis
Umuthi

I-Pseudomembranous colitis

I-P eudomembranou coliti i ho ukuvuvukala noma ukuvuvukala kwamathumbu amakhulu (ikholoni) ngenxa yokugcwala AmaClo tridioide difficile (C ukwehlukana) amabhaktheriya.Le i ifo iyimbangela ejwayelekile...
I-Serum progesterone
Umuthi

I-Serum progesterone

I- erum proge terone i ivivinyo okulingani a inani le-proge terone egazini. IProge terone iyi-hormone ekhiqizwa ikakhulu kuma-ovari.Iproge terone idlala indima enkulu ekukhulelweni. Ikhiqizwa ngemuva ...