Izimbangela ze-Alzheimer's: Ingabe Ifa?

-Delile

• Siyini isifo se-Alzheimer's?
• Isizathu # 1: Ukuguqulwa kwezakhi zofuzo
• Isizathu # 2: Ubudala
• Isizathu # 3: Ubulili
• Isizathu # 4: Ukuhlukumezeka kwekhanda okudlule
• Isizathu # 5: Ukukhubazeka okuncane kwengqondo
• Isizathu # 6: Indlela yokuphila nenhliziyo
• Isizathu # 7: Izinkinga zokulala
• Isizathu # 8: Ukuntuleka kokufunda impilo yonke

Ukwandisa amacala wesifo i-Alzheimer's

I-Alzheimer's Association ithi isifo i-Alzheimer siyimbangela yesithupha yokufa kwabantu e-United States, nokuthi abantu baseMelika abangaphezu kwezigidi ezinhlanu bayathinteka yilesi simo. Ngokwengeziwe, umuntu oyedwa kwabathathu asebekhulile ubulawa yi-Alzheimer's noma olunye uhlobo lokuwohloka komqondo. Lelo nani cishe lizonyuka njengoba inani labantu asebekhulile landa.

Ososayensi bebelokhu becwaninga i-Alzheimer’s amashumi eminyaka, kepha nokho alikho ikhambi. Funda kabanzi mayelana nokuthi izakhi zofuzo zihlobene kanjani nokwakhiwa kwe-Alzheimer's, kanye nezinye izimbangela zesimo.

Siyini isifo se-Alzheimer's?

Isifo i-Alzheimer silimaza ubuchopho bakho, konakalisa kancane kancane inkumbulo namakhono okucabanga. Abaphenyi bakholelwa ukuthi umonakalo uqala kuze kube yiminyaka eyishumi ngaphambi kokuba kuvele izimpawu. Ukufakwa okungajwayelekile kwamaprotheni kwakha izingcwecwe eziqinile nezingqimba kulo lonke ubuchopho. Lezi zimali ziphazamisa ukusebenza kwengqondo okuvamile.

Njengoba zikhula, izingcwecwe zingaphazamisa ukuxhumana phakathi kwezinzwa, izithunywa ezisengqondweni yakho. Ekugcineni la ma-neuron ayafa, alimaze ubuchopho bakho kangangokuba izingxenye zawo ziqale ukuncipha.

Isizathu # 1: Ukuguqulwa kwezakhi zofuzo

Isifo i-Alzheimer asiqondakali ngokuphelele. Ososayensi bakholelwa ukuthi kubantu abaningi, lesi sifo sinezakhi zofuzo, indlela yokuphila nezimo zemvelo. Zonke lezi zinto zingasebenzisana ukudala izimo ezifanele zokuthi lesi sifo simile.

Kukhona ingxenye yofuzo ku-Alzheimer's. Abantu abanabazali noma izingane zakwabo abanesifo basengozini ethe xaxa yokuba nesimo. Kodwa-ke, kusekude kakhulu ekuqondeni ukuguqulwa kwezakhi zofuzo okuholela ekwakhiweni kwangempela kwalesi sifo.

Isizathu # 2: Ubudala

Njengoba ukhula, uba sengcupheni yokuthola izinto ezingadala i-Alzheimer's. Ngo-2010, kwakukhona abantu abayizigidi ezingu-4.7 abaneminyaka engama-65 nangaphezulu abanesifo i-Alzheimer's. Kulezi, izigidi ezingama-0.7 zazineminyaka engama-65 kuya kwengama-74 ubudala, eziyizigidi ezingama-2.3 zazineminyaka engama-75 kuya kwengama-84 ubudala, kanti eziyizigidi eziyi-1.8 zazineminyaka engama-85 noma ngaphezulu.

Isizathu # 3: Ubulili

I-Alzheimer ithinta abesifazane abaningi kunabesilisa. Ososayensi bathi lokhu kungenxa yokuthi abesifazane ngokuvamile baphila isikhathi eside kunabesilisa. Ngenxa yalokho, abesifazane banamathuba amaningi okuthola lesi sifo lapho sebekhulile.

I-A isikisela ukuthi ama-hormone kungenzeka ahlangane nakho. Izinga le-hormone yabesifazane i-estrogen liyancipha emzimbeni wowesifazane ngemuva kokunqamuka kokuya esikhathini. Abaphenyi bakholelwa ukuthi i-hormone ivikela ubuchopho besifazane abasebasha ekulimaleni. Kepha njengoba amazinga ehla ebudaleni, amangqamuzana obuchopho aba sengozini yokuthola lesi sifo.

Isizathu # 4: Ukuhlukumezeka kwekhanda okudlule

I-Alzheimer's Association ithi ososayensi bathole ukuxhumana phakathi kokulimala kwengqondo ebucayi kanye nengozi enkulu yokuwohloka komqondo. Ngemuva kokulimala okubuhlungu, ubuchopho bakho budala inani elikhulu le-beta amyloid. Le yiprotheni efanayo ekhula ibe izingcwecwe ezilimazayo eziwuphawu lwe-Alzheimer's.

Kunokwehluka okukodwa: Ngemuva kokulimala kwengqondo okuhlukumezayo, i-beta amyloid, yize ikhona, ayihlanganisi izingcwecwe. Kodwa-ke, umonakalo ungakhuphula ubungozi bokwenza kanjalo kamuva empilweni.

Isizathu # 5: Ukukhubazeka okuncane kwengqondo

Abantu asebevele benokukhubazeka okuncane kwengqondo bangaba sengozini eyengeziwe yokuthuthukisa i-Alzheimer egcwele. Ukukhubazeka okuncane kwengqondo akuhambisani nempilo yomuntu yansuku zonke ngendlela enkulu. Kodwa-ke, ingaba nemiphumela ethile kwimemori, emakhono okucabanga, ekuboneni okubonakalayo, nasekhonweni lokwenza izinqumo ezizwakalayo.

Ososayensi bazama ukuqonda ukuthi kungani ezinye izimo zokukhubazeka okuncane kwengqondo ziqhubekela phambili zibe yi-Alzheimer's. A kukhombisa ukuthi ukutholakala kwamaprotheni athile ebuchosheni, njenge-beta amyloid, kwandisa ubungozi besifo.

Isizathu # 6: Indlela yokuphila nenhliziyo

Indlela yakho yokuphila ingahle ihlangane kakhulu namathuba akho okuthuthukisa i-Alzheimer's. Impilo yenhliziyo ikakhulukazi ibonakala ihlobene kakhulu nempilo yobuchopho. Ukudla ukudla okunempilo, ukuzivocavoca umzimba njalo, ukuyeka ukubhema, ukulawula isifo sikashukela, nokulawula umfutho wegazi ne-cholesterol konke kuyinhliziyo enhle. Futhi zingagcina ubuchopho bunempilo futhi buqinile.

Abantu abadala asebekhulile abane-coronary artery disease noma i-peripheral arterial disease basengozini enkulu yokuwohloka komqondo nesifo i-Alzheimer's.

Isizathu # 7: Izinkinga zokulala

Olunye ucwaningo lubonisa ukuthi ukulala kwekhwalithi kungabalulekile ekuvikeleni isifo se-Alzheimer's. Ucwaningo lwango-2013 olushicilelwe kubantu abadala abahlolisisiwe abaneminyaka elinganiselwa kwengu-76 ababengatholakali benalesi sifo. Labo abathola ubuthongo obubi noma obulinganiselwe babenokwanda okwengeziwe kwamapulangwe e-beta amyloid ebuchosheni babo.

Izifundo eziningi zidinga ukwenziwa. Ososayensi abasenaso isiqiniseko sokuthi ukulala kabi kuyimbangela ye-Alzheimer's noma ukuthi ngabe izigaba zokuqala zesifo zingathinta ukulala. Kokubili kungaba yiqiniso.

Isizathu # 8: Ukuntuleka kokufunda impilo yonke

Ubusebenzisa kangakanani ubuchopho bakho phakathi nempilo yakho nakho kungathinta ubungozi bakho be-Alzheimer's. Ucwaningo lwango-2012 lwabika ukuthi abantu ababevusa njalo ubuchopho babo ngemisebenzi eyinselele yengqondo babenamadiphozithi ama-beta amyloid ambalwa. Le misebenzi ibibalulekile kukho konke ukuphila. Kepha imizamo yokuphila kwasekuqaleni naphakathi yayihlotshaniswa nokwehliswa okukhulu kwengozi.

Amazinga aphezulu emfundo ehlelekile, umsebenzi ovuselelayo, imisebenzi yokuzilibazisa eyinselele ngokwengqondo, kanye nokuxhumana okuvamile komphakathi nakho kungavikela impilo yobuchopho.