Indlala ye-antiperoxidase: iyini nokuthi kungani ingaba phezulu

-Delile

• I-Antiperoxidase ephezulu ye-Thyroid
• 1. IHashimoto's thyroiditis
• 2. Isifo samathuna
• 3. Ukukhulelwa
• 4. I-subclinical hypothyroidism
• 5. Umlando womndeni

I-thyroid antiperoxidase (anti-TPO) i-antibody ekhiqizwa amasosha omzimba ahlasela indlala yegilo, okuholela ekushintsheni emazingeni ama-hormone akhiqizwa yi-thyroid. Amanani we-Anti-TPO ayahlukahluka kuye ngelebhu kuya kwilabhorethri, ngamanani akhulisiwe ngokuvamile akhombisa izifo ezizimele.

Kodwa-ke, inani lalesi sifo se-autoantibody lingakhuphuka ezimeni eziningana, ngakho-ke kubalulekile ukuthi ukuxilongwa kwenziwe ngokucatshangelwa umphumela wokunye ukuhlolwa okuhlobene ne-thyroid, njengamanye ama-autoantibodies wegciwane kanye nomthamo we-TSH, T3 no-T4. Yazi izivivinyo ezikhonjisiwe ukuhlola i-thyroid.

I-Antiperoxidase ephezulu ye-Thyroid

Amanani akhuphukile we-thyroid antiperoxidase (anti-TPO) ngokuvamile akhombisa izifo ezizimele zomzimba, njenge-Hashimoto's thyroiditis kanye nesifo se-Graves, isibonelo, noma kunjalo kungakhuphuka kwezinye izimo, njengokukhulelwa kanye ne-hypothyroidism. Izimbangela eziyinhloko zokwanda kwe-thyroid antiperoxidase yilezi:

1. IHashimoto's thyroiditis

IHashimoto's thyroiditis yisifo esizimele lapho amasosha omzimba ehlasela i-thyroid, ephazamisa ukukhiqizwa kwamahomoni e-thyroid futhi aholele ezimpawu ze-hypothyroidism, njengokukhathala ngokweqile, ukukhuluphala kwesisindo, ubuhlungu bemisipha nokwenza buthakathaka izinwele nezinzipho.

IHashimoto's thyroiditis ingenye yezimbangela ezinkulu zokwanda kwe-thyroid antiperoxidase, kepha kuyadingeka ukwenza ezinye izivivinyo ukuze kuqedelwe ukuxilongwa. Qonda ukuthi iyini iHashimoto's thyroiditis, izimpawu nokuthi ungayelapha kanjani.

2. Isifo samathuna

Isifo se-Graves ngesinye sezimo eziyinhloko lapho i-thyroid antiperoxidase iphezulu futhi yenzeka ngoba le autoantibody isebenza ngqo ku-thyroid futhi ivuselele ukukhiqizwa kwamahomoni, okuholele ekutheni kube nezimpawu zesifo, njengekhanda, amehlo abanzi, ukwehla kwesisindo, umjuluko, ubuthakathaka bemisipha nokuvuvukala emphinjeni, isibonelo.

Kubalulekile ukuthi isifo se-Graves sikhonjwe futhi silashwe ngendlela efanele ukunciphisa izimpawu, ukwelashwa okukhonjiswa udokotela ngokobukhulu besifo, nokusetshenziswa kwemithi, ukwelashwa iodine noma ukuhlinzwa kwegilo kunganconywa. Funda kabanzi ngesifo samathuna nokuthi siphathwa kanjani.

3. Ukukhulelwa

Ngenxa yezinguquko zamahomoni ezivame ukukhulelwa, kungenzeka ukuthi kukhona nezinguquko ezihlobene nendlala yegilo, engabonakala, kufaka phakathi, ukwanda kwamazinga e-thyroid antiperoxidase egazini.

Ngaphandle kwalokhu, owesifazane okhulelwe akanazo izinguquko ku-thyroid. Ngakho-ke, kubalulekile ukukala i-anti-TPO ekuqaleni kokukhulelwa ukuze udokotela akwazi ukuqapha amazinga ngesikhathi sokukhulelwa futhi abheke ubungozi bokuthola i-thyroiditis ngemuva kokubeletha, isibonelo.

4. I-subclinical hypothyroidism

I-subclinical hypothyroidism ibonakala ngokuncipha komsebenzi wendlala yegilo engazivezi izimpawu futhi okubonwa kuphela ngokuhlolwa kwegazi, lapho kuqinisekiswa khona amazinga ajwayelekile we-T4 kanye ne-TSH eyandisiwe.

Yize umthamo we-anti-TPO engakhonjiswa ngokujwayelekile ekutholeni i-subclinical hypothyroidism, udokotela anga-oda lokhu kuhlola ukuhlola ukuqhubeka kwe-hypothyroidism nokuqinisekisa ukuthi ngabe umuntu uphendula kahle yini ekwelashweni. Lokhu kungenzeka ngoba le antibody isebenza ngqo ku-enzyme elawula ukukhiqizwa kwamahomoni wegilo. Ngakho-ke, lapho ulinganisa i-antiperoxidase ye-thyroid ku-subclinical hypothyroidism, kungenzeka ukuqinisekisa ukuthi ukwehla kwenani le-anti-TPO kuhambisana nokwenziwa kwamazinga we-TSH egazini.

Funda ukuthi ungabona kanjani futhi welaphe i-hypothyroidism.

5. Umlando womndeni

Abantu abanezihlobo ezinezifo ze-thyroid ezenzakalelayo bangase bashintshe amanani we-thyroid antiperoxidase antibody, okungeyona inkomba yokuthi banesifo. Ngakho-ke, kubalulekile ukuthi inani le-anti-TPO lihlolwe kanye nezinye izivivinyo ezicelwe ngudokotela.