I-Apixaban, Ithebhulethi Yomlomo

-Delile

• Izexwayiso ezibalulekile
• Izexwayiso ze-FDA
  
• Ezinye izexwayiso
• Yini i-apixaban?
• Kungani kusetshenziswa
• Isebenza kanjani
• Imiphumela emibi ye-Apixaban
• Imiphumela emibi ejwayelekile
• Imiphumela emibi kakhulu
• I-Apixaban ingaxhumana neminye imithi
• Izidakamizwa ze-Anticoagulant noma antiplatelet
• Izidakamizwa ezivimbela i-CYP3A4 ne-P-glycoprotein
• Izidakamizwa ezenza i-CYP3A4 ne-P-glycoprotein
• Izexwayiso ze-Apixaban
• Isexwayiso somzimba
• Izexwayiso zabantu abanezimo ezithile zempilo
• Izexwayiso kwamanye amaqembu
• Ukushayela nini udokotela
  
• Ungayithatha kanjani i-apixaban
• Ifomu lezidakamizwa namandla
• Isikali sokunciphisa ubungozi bokushaywa unhlangothi kanye namahlule egazi kubantu abane-fibrillation ye-atrial
• Isikali sokunciphisa ubungozi bamahlule egazini kubantu abasanda kuhlinzwa okhalweni noma emadolweni
• Isikali se-vein thrombosis ejulile kanye ne-embolism ye-pulmonary
• Isikali sokunciphisa ubungozi be-vein thrombosis ejulile kanye ne-embolism ye-pulmonary
• Thatha njengoba kuqondisiwe
• Ukucatshangelwa okubalulekile kokuthatha i-apixaban
• Jikelele
• Isitoreji
• Ukugcwalisa kabusha
• Ukuvakasha
• Ukuqapha komtholampilo
• Ukutholakala
• Ngaphambi kokugunyazwa
• Ingabe zikhona ezinye izindlela?

Okuvelele kwe-apixaban

1. Ithebhulethi yomlomo ye-Apixaban iyatholakala njengesidakamizwa esinegama lomkhiqizo. Ayinayo inguqulo ejwayelekile. Igama lomkhiqizo: Eliquis.
2. I-Apixaban iza kuphela njengethebhulethi oyithatha ngomlomo.
3. I-Apixaban isetshenziselwa ukwelapha nokuvikela amahlule egazi afana ne-vein thrombosis ejulile kanye ne-pulmonary embolism. Kuyasiza futhi ukunciphisa ingozi yokushaywa unhlangothi uma une-fibrillation ye-atrial ngaphandle kwe-valve yenhliziyo yokufakelwa.

Izexwayiso ezibalulekile

Izexwayiso ze-FDA

• Lo muthi unezixwayiso zebhokisi elimnyama. Lezi izexwayiso ezibucayi kakhulu ezivela ku-Food and Drug Administration (FDA). Izixwayiso zebhokisi elimnyama zixwayisa odokotela neziguli ngemiphumela yezidakamizwa engaba yingozi.
• Ukumisa ukwelashwa isexwayiso sokuqala: Ungayeki ukuthatha lesi sidakamizwa ngaphandle kokukhuluma nodokotela wakho kuqala. Ukumisa lesi sidakamizwa kwandisa ingozi yokuba nesifo sohlangothi nokuthuthukisa amahlule egazi. Lesi sidakamizwa singadinga ukumiswa ngaphambi kokuhlinzwa noma inqubo yezokwelapha noma yamazinyo. Udokotela wakho uzokutshela ukuthi ungayeka kanjani ukuyithatha nokuthi ungaqala nini ukuyithatha futhi. Ngenkathi umuthi umisiwe, udokotela wakho angakunikeza omunye umuthi wokusiza ukugcina amahlule egazi angakhi.
• Isixwayiso sengcuphe yegazi lomgogodla noma le-epidural: Uma uthatha lo muthi futhi ufakwa omunye umjovo emgogodleni wakho, noma uma ubhoboza umgogodla, ungaba sengozini yokuqina kwegazi okunzima. Ukuqina kwegazi lomgogodla noma kwe-epidural kungadala ukukhubazeka.
  
  Ingozi yakho iba nkulu uma kufakwa ithubhu elincanyana elibizwa ngokuthi i-epidural catheter emhlane wakho ukukunika imithi. Kuphezulu uma uthatha imishanguzo yokulwa nokuvuvukala (ama-NSAID) noma ama-anticoagulants. Kubuye kuphakame uma unomlando wezinhlamvu ezilukhuni noma eziphindaphindiwe ze-epidural noma zomgogodla noma umlando wezinkinga ngomgogodla wakho, noma uma uke wahlinzwa umgogodla wakho.
  
  Udokotela wakho uzokubheka nganoma yiziphi izimpawu zokugawulwa kwegazi lomgogodla noma le-epidural. Tshela udokotela wakho uma unezimpawu. Lokhu kungabandakanya ukuncipha, ukuba ndikindiki, noma ubuthakathaka bemisipha, ikakhulukazi emilenzeni nasezinyaweni, noma ukwehluleka ukulawula isinye noma amathumbu akho.

Ezinye izexwayiso

• Isixwayiso sengozi yokopha: Lesi sidakamizwa sandisa ingozi yokuphuma kwegazi. Lokhu kungaba kubi noma kubulale. Lokhu kungenxa yokuthi lo muthi uyisidakamizwa esinciphisa igazi esinciphisa ubungozi bamahlule egazi emzimbeni wakho. Shayela udokotela wakho noma uye egumbini labezimo eziphuthumayo ngokushesha uma unezimpawu zokopha okukhulu. Uma kudingeka, umhlinzeki wezokunakekelwa kwezempilo anganikeza ukwelashwa ukuguqula imiphumela yokuncipha kwegazi ye-apixaban.
• Izimpawu zokopha okufanele uzibuke zifaka:
  • ukopha okungalindelekile noma ukopha okuhlala isikhathi eside, okufana nokopha kaningi, ukopha okungavamile ezinsinini zakho, ukopha kokuya esikhathini okunzima kunokujwayelekile, noma okunye ukuphuma kwegazi esithweni sangasese
  • ukopha okunzima noma ongeke ukwazi ukukulawula
  • umchamo obomvu-, opinki-, noma onsundu
  • izitulo ezikhanyayo ezibomvu noma ezimnyama ezifana netiyela
  • ukukhwehlela igazi noma amahlule egazi
  • uhlanza igazi noma uhlanza olubukeka njengezizathu zekhofi
  • ikhanda, isiyezi, noma ubuthakathaka
  • ubuhlungu, ukuvuvukala, noma amanzi amasha ezindaweni zamanxeba
• Isixwayiso se-valve yenhliziyo yokufakelwa: Ungasebenzisi lesi sidakamizwa uma une-valve yenhliziyo yokufakelwa. Akwaziwa ukuthi lo muthi uzokusebenzela yini.
• Inqubo yokuxwayisa ngenqubo yezokwelapha noma yamazinyo: Ungadinga ukuyeka okwesikhashana ukuthatha lo muthi ngaphambi kokuhlinzwa noma inqubo yezokwelapha noma yamazinyo. Udokotela wakho uzokutshela ukuthi ungayeka kanjani ukuyithatha nokuthi ungaqala nini ukuyithatha futhi. Ngenkathi umuthi umisiwe, udokotela wakho angahle anikeze omunye umuthi ukusiza ukugcina amahlule egazi angakhi.

Yini i-apixaban?

I-Apixaban ngumuthi kadokotela. Kuza njengethebhulethi yomlomo.

I-Apixaban iyatholakala njengesidakamizwa esinegama lomkhiqizo U-Eliquis. Akutholakali njengomuthi ojwayelekile.

Kungani kusetshenziswa

I-Apixaban isetshenziselwa:

• yehlisa ingozi yamahlule egazi nesifo sohlangothi uma une-fibrillation ye-atrial ngaphandle kwe-valve yenhliziyo yokufakelwa
• ukuvimbela i-vein thrombosis ejulile (i-clot yegazi emilenzeni yakho) noma i-pulmonary embolism (i-clot yegazi emaphashini akho) ngemuva kokuhlinzwa kwesinqe noma idolo
• ukuvimbela okunye ukwenzeka kwe-vein thrombosis (DVT) noma i-pulmonary embolism (PE) kubantu abanomlando noma i-DVT noma i-PE
• phatha i-DVT noma i-PE

Isebenza kanjani

I-Apixaban ingeyesigaba semithi ebizwa ngama-anticoagulants, ikakhulukazi i-Xa blocker. Isigaba semithi siyiqembu lemithi esebenza ngendlela efanayo. Le mithi ivame ukusetshenziselwa ukwelapha izimo ezifanayo.

I-Apixaban yincipha yegazi futhi isiza ukuvimbela amahlule egazi ukuthi akhe emzimbeni wakho. Lokhu ikwenza ngokuvimba into eyi-Xa, yona eyehlise inani le-enzyme thrombin egazini lakho. I-Thrombin yinto ebangela ukuthi amaplatelets egazini lakho anamathele komunye nomunye, okwenza amahlule abe khona. Lapho i-thrombin yehla, lokhu kuvimbela i-clot (thrombus) ekwakhiweni komzimba wakho.

Imiphumela emibi ye-Apixaban

Ithebhulethi yomlomo ye-Apixaban ayibangeli ukozela, kepha ingadala eminye imiphumela emibi.

Imiphumela emibi ejwayelekile

Imiphumela emibi ejwayelekile engenzeka nge-apixaban ifaka:

• Ukopha. Izimpawu zingafaka:
  • ukuphuma kwamakhala
  • ukulimaza kalula
  • ukuphuma kwegazi okunzima
  • ukopha kwezinsini zakho lapho uxubha amazinyo

Uma le miphumela imnene, ingahle ihambe zingakapheli izinsuku ezimbalwa noma amasonto ambalwa. Uma zinzima kakhulu noma zingahambi, khuluma nodokotela wakho noma usokhemisi.

Imiphumela emibi kakhulu

Shayela udokotela wakho ngokushesha uma unemiphumela emibi kakhulu. Shayela u-911 uma izimpawu zakho zizizwa zisongela impilo noma uma ucabanga ukuthi unezimo eziphuthumayo zezokwelapha. Imiphumela emibi kanye nezimpawu zayo zingafaka okulandelayo:

• Ukopha okungathi sína. Lokhu kungabulala, izimpawu zingabandakanya:
  • ukopha okungalindelekile noma ukopha okuhlala isikhathi eside (kufaka phakathi ukopha okungavamile kusuka ezingubeni zakho, ukuphuma kwamakhala okwenzeka kaningi, noma ukuphuma kakhulu kokuya esikhathini)
  • ukopha okunzima noma okungalawuleki
  • umchamo obomvu-, opinki-, noma onsundu
  • umbala obomvu noma omnyama, izitulo zokulinda
  • ukukhwehlela igazi noma amahlule egazi
  • uhlanza igazi noma uhlanza olubukeka njengezizathu zekhofi
  • ubuhlungu obungalindelekile noma ukuvuvukala
  • ikhanda, isiyezi, noma ubuthakathaka
• Amahlule egazi lomgogodla noma we-epidural. Uma uthatha i-apixaban futhi ufakwa esinye isidakamizwa emgogodleni wakho, noma uma unesihlakala somgogodla, ungahle ube sengozini yokuqina kwegazi lomgogodla noma le-epidural. Lokhu kungaholela ekukhubazekeni unomphela. Izimpawu zingafaka:
  • ukuncinza, ukuba ndikindiki, noma ubuthakathaka bemisipha, ikakhulukazi emilenzeni nasezinyaweni
  • ukwehluleka ukulawula isinye noma amathumbu akho

Ukuzikhulula: Inhloso yethu ukukunikeza imininingwane efanelekile futhi yamanje. Kodwa-ke, ngoba izidakamizwa zithinta umuntu ngamunye ngokuhlukile, asikwazi ukuqinisekisa ukuthi lolu lwazi lubandakanya yonke imiphumela emibi engaba khona. Lolu lwazi aluyithathi indawo yeseluleko sezokwelapha. Hlala uxoxa ngemiphumela emibi engaba khona nomhlinzeki wezokunakekelwa kwempilo owazi umlando wakho wezokwelapha.

I-Apixaban ingaxhumana neminye imithi

Ithebhulethi yomlomo ye-Apixaban ingaxhumana neminye imithi, amavithamini, noma amakhambi ongahle uwuthathe. Ukusebenzisana kulapho into iguqula indlela umuthi osebenza ngayo. Lokhu kungaba yingozi noma kuvimbele umuthi ukuthi usebenze kahle.

Ukusiza ukugwema ukuxhumana, udokotela wakho kufanele aphathe yonke imithi yakho ngokucophelela. Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi, amavithamini, noma amakhambi owathathayo. Ukuthola ukuthi lo muthi ungahlangana kanjani nokunye okuthathayo, khuluma nodokotela wakho noma usokhemisi.

Izibonelo zemithi engadala ukusebenzisana ne-apixaban zibhalwe ngezansi.

Izidakamizwa ze-Anticoagulant noma antiplatelet

Ukusebenzisa i-apixaban nezinye izidakamizwa ezivela ekilasini elifanayo kwandisa ingozi yokuphuma kwegazi. Izibonelo zalezi ezinye izidakamizwa zifaka:

• warfarin
• i-heparin
• i-aspirin
• clopidogrel
• izidakamizwa ezingezona ukuvuvukala (ama-NSAID), njenge-ibuprofen noma i-naproxen

Izidakamizwa ezivimbela i-CYP3A4 ne-P-glycoprotein

I-Apixaban icutshungulwa ama-enzyme athile esibindini sakho (esaziwa njenge-CYP3A4) kanye nabathuthi emathunjini (abaziwa nge-P-gp). Imithi evimba la ma-enzyme nabathuthi inyusa inani le-apixaban emzimbeni wakho. Lokhu kukubeka engcupheni enkulu yokopha. Uma udinga ukuthatha i-apixaban ngesinye salezi zidakamizwa, udokotela wakho angehlisa isilinganiso sakho se-apixaban noma anikeze umuthi ohlukile.

Izibonelo zale mithi zifaka:

• ketoconazole
• itraconazole
• i-ritonavir

Izidakamizwa ezenza i-CYP3A4 ne-P-glycoprotein

I-Apixaban icutshungulwa ama-enzyme athile esibindi sakho (esaziwa nge-CYP3A4) kanye nabathuthi emathunjini (abaziwa nge-P-gp). Imithi ekhulisa umsebenzi walezi enzyme zesibindi nabahambisa amathumbu yehlisa inani le-apixaban emzimbeni wakho. Lokhu kukubeka engcupheni enkulu yokushaywa unhlangothi noma eminye imicimbi yokuvala igazi. Akufanele uthathe i-apixaban ngale mithi.

Izibonelo zale mithi zifaka:

• phumlani
• carbamazepine
• mthombeni
• Isibungu iSt

Ukuzikhulula: Inhloso yethu ukukunikeza imininingwane efanelekile futhi yamanje. Kodwa-ke, ngoba izidakamizwa zisebenzisana ngokwehlukile kumuntu ngamunye, asikwazi ukuqinisekisa ukuthi lolu lwazi lubandakanya konke ukuxhumana okungenzeka. Lolu lwazi aluyithathi indawo yeseluleko sezokwelapha. Hlala ukhuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nokuhlangana okungenzeka ngayo yonke imishanguzo kadokotela, amavithamini, amakhambi kanye nezithasiselo, kanye nemithi oyithenga uphuza yona.

Izexwayiso ze-Apixaban

Lesi sidakamizwa siza nezixwayiso eziningana.

Isexwayiso somzimba

Lesi sidakamizwa singadala ukusabela okweqile komzimba. Izimpawu zingafaka:

• ubuhlungu besifuba noma ukuqina
• ukuvuvukala kobuso bakho noma ulimi lwakho
• ukuphefumula kanzima noma ukuphefumula
• uzizwe unesiyezi noma uqulekile

Uma uthola ukusabela okweqile, shayela udokotela wakho noma isikhungo sendawo sokulawula ubuthi ngokushesha. Uma izimpawu zakho zinzima, shayela ku-911 noma uye egumbini lezimo eziphuthumayo eliseduze.

Ungaphinde uwuthathe lo muthi uma ngabe uke waba nokungezwani komzimba nawo. Ukuyithatha futhi kungaba yingozi (kungadala ukufa).

Izexwayiso zabantu abanezimo ezithile zempilo

Kubantu abanezinkinga zesibindi: Uma unezinkinga ezinzima zesibindi, akufanele uthathe lo muthi. Lesi sidakamizwa sicutshungulwa isibindi sakho. Uma isibindi sakho singasebenzi kahle, umuthi omningi ungahlala emzimbeni wakho. Lokhu kukubeka engozini yemiphumela emibi eminingi.

Kubantu abanezinkinga zezinso: Uma unezinkinga ezinzima zezinso, ungadinga isilinganiso esincane salomuthi. Uma izinso zakho zingasebenzi kahle, umuthi omningi ungahlala emzimbeni wakho. Lokhu kukubeka engozini yemiphumela emibi eminingi.

Kubantu abanegazi elisebenzayo: Uma wopha noma ulahlekelwa yigazi, akufanele uthathe lo muthi. Kungakhuphula ingozi yakho yokopha okungathi sína noma okubulalayo.

Izexwayiso kwamanye amaqembu

Kwabesifazane abakhulelwe: Lesi sidakamizwa singumuthi wesigaba B sokukhulelwa. Lokho kusho izinto ezimbili:

1. Izifundo zomuthi ezilwaneni ezikhulelwe azikhombisanga ubungozi enganeni.
2. Azikho izifundo ezanele ezenziwa kwabesifazane abakhulelwe ukukhombisa ukuthi umuthi ubeka engcupheni umbungu.

Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Lesi sidakamizwa kufanele sisetshenziswe ngesikhathi sokukhulelwa kuphela uma inzuzo engaba khona iqinisekisa ubungozi obungaba khona.

Kwabesifazane abancelisayo: Akukaziwa ukuthi ngabe lesi sidakamizwa sidlula ubisi lwebele. Uma kunjalo, kungadala imiphumela emibi enganeni enceliswa ibele. Wena nodokotela wakho kungadingeka ukuthi ninqume ukuthi uzowuphuza yini lo muthi noma uncelise.

Okwabadala: Njengoba ukhula, umzimba wakho kungenzeka ungazisebenzisi izidakamizwa njengoba wawukwenza. Lokhu kungakhuphula ubungozi bakho bemiphumela emibi evela kulo muthi.

Okwezingane: Lo muthi awusungulwanga uphephile futhi usebenza kahle ekusetshenzisweni ezinganeni ezingaphansi kweminyaka eyi-18.

Kubantu abazobe behlinzwa: Uma uhlela ukuhlinzwa noma inqubo yezokwelapha noma yamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-apixaban. Udokotela wakho angamisa ukwelashwa kwakho nge-apixaban isikhashana. Ngenkathi umuthi umisiwe, bangahle banikeze omunye umuthi wokusiza ukugcina amahlule egazi angakhi.

• Uma uthola noma yikuphi ukuhlinzwa noma inqubo enengcuphe elinganiselayo noma ephezulu yokopha okukhulu, udokotela wakho uzokuyeka uyeke ukuthatha i-apixaban okungenani amahora angama-48 ngaphambi kwenqubo. Udokotela wakho uzokutshela ukuthi kulungile nini ukuqala ukuthatha umuthi futhi.
• Uma ngabe kukhona ukuhlinzwa noma inqubo enengozi ephansi yokopha noma lapho ukuphuma kwegazi kungalawulwa khona, udokotela wakho uzokuyeka uyeke ukuthatha i-apixaban okungenani amahora angama-24 ngaphambi kwenqubo. Udokotela wakho uzokutshela ukuthi kulungile nini ukuqala ukuthatha umuthi futhi.

Ukushayela nini udokotela

1. Shayela udokotela wakho ngokushesha uma uwa noma uzilimaza, ikakhulukazi uma ushaya ikhanda. Udokotela wakho kungadingeka ukuthi ahlole ukuthi wopha ngaphakathi emzimbeni wakho.

Ungayithatha kanjani i-apixaban

Yonke imithamo namafomu okungenzeka angafakwa lapha. Umthamo wakho, ifomu, nokuthi ulithatha kangaki kuzoya ngokuthi:

• iminyaka yakho
• isimo esilashwa
• ubunzima besimo sakho
• ezinye izimo zezokwelapha onazo
• ukuthi usabela kanjani esilinganisweni sokuqala

Ifomu lezidakamizwa namandla

Umkhiqizo: U-Eliquis

• Ifomu: ithebhulethi yomlomo
• Amandla: 2.5 mg no-5 mg

Isikali sokunciphisa ubungozi bokushaywa unhlangothi kanye namahlule egazi kubantu abane-fibrillation ye-atrial

Isikali sabadala (iminyaka eyi-18-79 yeminyaka)

Umthamo ojwayelekile u-5 mg uthathwe izikhathi ezimbili ngosuku.

Isilinganiso sengane (iminyaka yobudala engu-0-17)

Umthamo ophephile futhi osebenzayo awusungulwanga leli qembu leminyaka.

Umthamo omkhulu (uneminyaka engama-80 nangaphezulu)

Uma unezinkinga ezinzima zezinso noma unesisindo esingaphansi noma esilingana namakhilogremu ayi-132, udokotela wakho angakwehlisa umthamo wakho. Uma izinso zakho zingasebenzi kahle, umuthi omningi ungahlala emzimbeni wakho. Lokhu kukubeka engcupheni enkulu yemiphumela emibi.

Ukucatshangelwa okukhethekile komthamo

Kubantu abanezinkinga zezinso: Uma izinso zakho zingasebenzi kahle, umuthi omningi ungahlala emzimbeni wakho. Lokhu kukubeka engcupheni enkulu yemiphumela emibi.

• Uma unezinkinga ezinzima zezinso futhi uku-dialysis, isilinganiso sakho kufanele sithathwe u-5 mg kabili ngosuku.
• Uma uneminyaka yobudala engama-80 noma ngaphezulu noma uma unesisindo esingaphansi kwamakhilogremu ayi-132 (60 kg), isilinganiso sakho kufanele sibe ngu-2.5 mg othathwa kabili ngosuku.

Kubantu abanesisindo somzimba esiphansi: Uma unesisindo esingaphansi noma esilingana namakhilogremu ayi-132 (60 kg), futhi unezinkinga zezinso noma uneminyaka yobudala engama-80 noma ngaphezulu, isilinganiso esinconywayo ngu-2.5 mg othathwa kabili ngosuku.

Isikali sokunciphisa ubungozi bamahlule egazini kubantu abasanda kuhlinzwa okhalweni noma emadolweni

Isilinganiso sabadala (iminyaka engu-18 nangaphezulu)

• Umthamo ojwayelekile ngu-2.5 mg othathwa izikhathi ezimbili ngosuku.
• Kufanele uthathe umthamo wakho wokuqala amahora ayi-12 kuye kwangama-24 ngemuva kokuhlinzwa.
• Ngokuhlinzwa kwe-hip, ukwelashwa kwakho nge-apixaban kuzohlala izinsuku ezingama-35.
• Ngokuhlinzwa kwamadolo, ukwelashwa kwakho nge-apixaban kuzohlala izinsuku eziyi-12.

Isilinganiso sengane (iminyaka engu-0 kuye kwengu-17)

Umthamo ophephile futhi osebenzayo awusungulwanga leli qembu leminyaka.

Isikali se-vein thrombosis ejulile kanye ne-embolism ye-pulmonary

Isilinganiso sabadala (iminyaka engu-18 nangaphezulu)

Umthamo ojwayelekile uthathwa ngo-10 mg izikhathi ezimbili ngosuku izinsuku ezingama-7. Ngemuva kwalokho, ngu-5 mg othathwe izikhathi ezimbili ngosuku okungenani izinyanga eziyisithupha.

Isilinganiso sengane (iminyaka engu-0 kuye kwengu-17)

Umthamo ophephile futhi osebenzayo awusungulwanga leli qembu leminyaka.

Isikali sokunciphisa ubungozi be-vein thrombosis ejulile kanye ne-embolism ye-pulmonary

Isilinganiso sabadala (iminyaka engu-18 nangaphezulu)

Umthamo ojwayelekile ngu-2.5 mg othathwa izikhathi ezimbili ngosuku. Kufanele uthathe lesi sidakamizwa ngemuva kwezinyanga okungenani eziyisithupha zokwelashwa kwe-DVT noma i-PE.

Isilinganiso sengane (iminyaka engu-0 kuye kwengu-17)

Umthamo ophephile futhi osebenzayo awusungulwanga leli qembu leminyaka.

Ukuzikhulula: Inhloso yethu ukukunikeza imininingwane efanelekile futhi yamanje. Kodwa-ke, ngoba izidakamizwa zithinta umuntu ngamunye ngokuhlukile, asikwazi ukuqinisekisa ukuthi lolu hlu lubandakanya yonke imithamo engenzeka. Lolu lwazi aluyithathi indawo yeseluleko sezokwelapha. Hlala ukhuluma nodokotela wakho noma usokhemisi ngemithamo ekufanele.

Thatha njengoba kuqondisiwe

Ithebhulethi yomlomo ye-Apixaban ingasetshenziselwa ukwelashwa kwesikhashana noma kwesikhathi eside. Udokotela wakho uzonquma ukuthi kufanele uwuthathe isikhathi esingakanani lo muthi. Ungayeki ukuyithatha ngaphandle kokukhuluma nodokotela wakho kuqala.

I-Apixaban iza nezingozi ezinkulu uma ungayithathi njengokuyalelwe.

Uma uphuthelwa umthamo: Uma uphuthelwa umthamo, wuthathe ngokushesha lapho ukhumbula ngosuku olufanayo. Bese ubuyela esimisweni sakho esivamile. Ungathathi umthamo ongaphezu kowodwa walo muthi ngesikhathi esisodwa ukuzama ukwenza umthamo ongabanjwanga.

Uma uyeka ukuyithatha: Ukumisa lesi sidakamizwa kungandisa ingozi yokushaywa unhlangothi noma amahlule egazi. Qiniseka ukuthi ugcwalisa umuthi wakho ngaphambi kokuphela. Uma uhlela ukuhlinzwa noma inqubo yezokwelapha noma yamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha lo muthi. Ungadinga ukumisa okwesikhashana ukuyithatha.

Uma uthatha kakhulu: Uma uthatha okungaphezu komthamo wakho onqunyiwe walesi sidakamizwa, unengozi enkulu yokopha. Lokhu kungaba kubi futhi kubulale nokufa. Uma ucabanga ukuthi uthathe kakhulu lo muthi, shayela udokotela wakho noma uye egumbini lezimo eziphuthumayo ngokushesha.

Ungatshela kanjani ukuthi umuthi uyasebenza: Lapho usebenzisa lesi sidakamizwa ukunciphisa ubungozi bamahlule egazi, ungahle ungakwazi ukusho ukuthi umuthi uyasebenza yini. Imithi yayenzelwe ukuthi kungadingeki uthole izivivinyo ezijwayelekile ukuze ubone ukuthi iyasebenza yini. Udokotela wakho angenza izivivinyo ukuhlola amazinga egazi alo muthi, kodwa lokhu akuvamile kakhulu.

Ngokwelapha i-DVT ne-PE, ungakwazi ukutshela ukuthi kuyasebenza uma izimpawu zakho zithuthuka.

Ukucatshangelwa okubalulekile kokuthatha i-apixaban

Gcina lokhu kubheka engqondweni uma udokotela wakho ekutshela i-apixaban.

Jikelele

• Ungathatha lesi sidakamizwa ngokudla noma ngaphandle kokudla.
• Uma ungakwazi ukugwinya amaphilisi aphelele:
  • Amaphilisi e-Apixaban angachotshozwa ahlanganiswe namanzi, ijusi le-apula, noma i-appleauce. Ungabasebenzisa ngomlomo. Qiniseka ukuthi uphuza umuthi kungakapheli amahora amane wokuchoboza amaphilisi.
  • Uma uneshubhu le-nasogastric, udokotela wakho angawuchoboza lo muthi, awuhlanganise nesisombululo samanzi se-dextrose, bese ekunika umuthi ngeshubhu.

Isitoreji

• Gcina ekamelweni lokushisa: 68-77 ° F (20-25 ° C).
• Ungawugcini lo muthi ezindaweni ezinomswakama noma ezinomswakama, njengezindlu zangasese.

Ukugcwalisa kabusha

Imibhalo kadokotela yalomuthi iyagcwaliseka. Akudingeki ukuthi unikezwe umuthi omusha kadokotela ukuze ugcwaliswe futhi lo muthi. Udokotela wakho uzobhala inani lama-refill eligunyazwe kudokotela wakho.

Ukuvakasha

Lapho uhamba nemithi yakho:

• Ngaso sonke isikhathi phatha imithi yakho. Lapho undiza, ungalokothi uwufake esikhwameni esihloliwe. Yigcine esikhwameni sakho sokuthwala.
• Ungakhathazeki ngemishini ye-X-ray yesikhumulo sezindiza. Abakwazi ukulimaza umuthi wakho.
• Ungadinga ukukhombisa abasebenzi bezindiza ilebula lekhemisi lemithi yakho. Ngaso sonke isikhathi phatha isitsha sokuqala esinelebula kadokotela.
• Ungafaki lo muthi egumbini legilavu ​​lemoto yakho noma uwushiye emotweni. Qinisekisa ukugwema ukwenza lokhu lapho isimo sezulu sishisa kakhulu noma sibanda kakhulu.

Ukuqapha komtholampilo

Udokotela wakho angahlola okulandelayo ngesikhathi sokwelashwa kwakho:

• Umsebenzi wezinso. Udokotela wakho angenza ukuhlolwa kwegazi ukuze abheke ukuthi izinso zakho zisebenza kahle kangakanani. Uma unezinkinga zezinso, umzimba wakho ngeke ukwazi ukusikhipha lesi sidakamizwa. Lokhu kungadala ukuthi lo muthi uhlale emzimbeni wakho, okuzokhulisa ubungozi bemiphumela emibi.
• Umsebenzi wesibindi. Udokotela wakho angenza ukuhlolwa kwegazi ukuze abheke ukuthi isibindi sakho sisebenza kahle kangakanani. Uma isibindi sakho singasebenzi kahle, umuthi omningi ungahlala emzimbeni wakho. Lokhu kukubeka engozini yemiphumela emibi eminingi.

Ukutholakala

Akuwona wonke amakhemisi agcina lo muthi. Lapho ugcwalisa incwadi kadokotela, qiniseka ukuthi ushayela phambili ukuze uqiniseke ukuthi ikhemisi lakho liyawuphatha.

Ngaphambi kokugunyazwa

Izinkampani eziningi zomshuwalense zidinga ukugunyazwa kwangaphambili kwalomuthi. Lokhu kusho ukuthi udokotela wakho uzodinga ukuthola imvume enkampanini yakho yomshuwalense ngaphambi kokuba inkampani yakho yomshuwalense ikhokhele incwadi kadokotela.

Ingabe zikhona ezinye izindlela?

Kuneminye imithi etholakalayo yokwelapha isimo sakho. Ezinye zingakulungela kangcono kunabanye. Khuluma nodokotela wakho ngezinye izinketho zezidakamizwa ezingakusebenzela.

Ukuzikhulula: I-Healthline yenze yonke imizamo yokuqinisekisa ukuthi lonke ulwazi luyiqiniso, luphelele futhi lusesikhathini. Kodwa-ke, le ndatshana akufanele isetshenziswe njengokungena esikhundleni solwazi nobungoti bochwepheshe bezokunakekelwa kwezempilo onelayisense. Kufanele uhlale uthintana nodokotela wakho noma omunye uchwepheshe wezokunakekelwa kwempilo ngaphambi kokuthatha noma imuphi umuthi. Imininingwane yezidakamizwa equkethwe lapha ingashintsha futhi ayihloselwe ukumboza konke ukusetshenziswa okungaba khona, izinkomba, izixwayiso, izexwayiso, ukuxhumana kwezidakamizwa, ukungezwani komzimba, noma imiphumela emibi. Ukungabikho kwezixwayiso noma olunye ulwazi lomuthi othile awukhombisi ukuthi inhlanganisela yezidakamizwa noma yezidakamizwa iphephile, iyasebenza, noma ilungele zonke iziguli noma konke ukusetshenziswa okuthile.