Yini Ebangela Ukwehluleka Kwe-Exocrine Pancreatic?

-Delile

• Iyini i-EPI?
• Yini Ebangela i-EPI?
• I-Pancreatitis engapheli
• Pancreatitis enamandla
• I-Autoimmune Pancreatitis
• Isifo sikashukela
• Ukuhlinzwa
• Izimo Zofuzo
• Isifo seCeliac
• Umdlavuza wePancreatic
• Izifo Zamathumbu Okuvuvukala
• IZollinger-Ellison Syndrome
• Ngingavimbela i-EPI?

Iyini i-EPI?

Ama-pancreas akho adlala indima ebalulekile ohlelweni lwakho lokugaya ukudla. Umsebenzi wawo ukwenza nokukhulula ama-enzyme asiza uhlelo lwakho lokugaya ukudla ukudiliza ukudla futhi lumunce izakhi zomzimba. Ukungakwazi ukusebenza kahle kwepancreatic (EPI) kuvela lapho amanyikwe engenzi noma ahambise ngokwanele kulawo ma-enzyme. Lokho kushoda kwe-enzyme kwenza kube nzima ngomzimba wakho ukuguqula ukudla kube yizinhlobo zohlelo lokugaya ukudla ongalusebenzisa

Izimpawu ze-EPI ziqapheleka kakhulu lapho kukhiqizwa i-enzyme ebhekele ukwehlisa amafutha kwehle iye emaphesentini amahlanu kuya kwayishumi evamile. Uma lokhu kwenzeka ungahle wehlise isisindo, uhudo, indle enamafutha nezimpawu ezinamafutha ezihambisana nokungondleki.

Yini Ebangela i-EPI?

I-EPI yenzeka lapho amanyikwe akho eyeka ukukhipha ama-enzyme anele ukuxhasa ukugaya ukudla okuvamile.

Izimo ezahlukahlukene zingalimaza amanyikwe akho futhi ziholele ku-EPI. Ezinye zazo, njenge-pancreatitis, zidala i-EPI ngokulimaza ngqo amaseli e-pancreatic enza ama-enzyme wokugaya ukudla. Izimo ezizuzwe njengeSshwachman-Diamond syndrome kanye ne-cystic fibrosis nazo zingadala i-EPI, njengokuhlinzwa kwepancreatic noma isisu.

I-Pancreatitis engapheli

I-pancreatitis engapheli ukuvuvukala kwamanyikwe akho okungapheli ngokuhamba kwesikhathi. Leli fomu le-pancreatitis liyimbangela evame kakhulu ye-EPI kubantu abadala. Ukuvuvukala okuqhubekayo kwamanyikwe kulimaza amaseli enza ama-enzyme wokugaya ukudla. Yingakho abantu abaningi abane-pancreatitis eqhubekayo futhi bekhulisa ukungasebenzi kahle kwe-exocrine.

Pancreatitis enamandla

Uma kuqhathaniswa ne-pancreatitis engapheli, i-EPI ayijwayelekile kakhulu ku-pancreatitis eza futhi idlule isikhathi esifushane. I-pancreatitis engalashwa engahle ikhule ibe yifomu elingapheli ngokuhamba kwesikhathi, ikhulise amathuba akho okuba ne-EPI.

I-Autoimmune Pancreatitis

Lolu uhlobo lwe-pancreatitis oluqhubekayo olwenzeka lapho amasosha akho omzimba ehlasela amanyikwe akho. Ukwelashwa kwe-steroid kungasiza abantu abane-autoimmune pancreatitis ukubona ukukhiqizwa kwe-enzyme okuthuthukisiwe.

Isifo sikashukela

Abantu abanesifo sikashukela bavame ukuba ne-EPI. Abaphenyi ababuqondi ngokugcwele ubudlelwane obuphakathi kwesifo sikashukela ne-EPI. Kungenzeka ukuthi ihlobene nokungalingani kwama-hormone okuhlangana nama-pancreas ngesikhathi sikashukela.

Ukuhlinzwa

I-EPI ingumphumela ojwayelekile ohlangothini lokugaya ukudla noma ukuhlinzwa kwamanyikwe. Ngokuya ngocwaningo oluningi lokuhlinzwa kwesisu, kuze kufike kubantu abahlinzekwe amanyikwe, isisu noma amathumbu amancane angenhla kuzoba ne-EPI.

Lapho udokotela ohlinzayo esusa wonke noma ingxenye yamanyikwe, ingaveza amanani amancane enzyme. Ukuhlinzwa kwesisu, kwamathumbu, nokwenhlanyelo nakho kungaholela ku-EPI ngokushintsha indlela uhlelo lwakho lokugaya ukudla olufanelana ngayo. Isibonelo, ukususa ingxenye yesisu kungaphazamisa ukucabanga kwamathumbu okudingekayo ukuxuba ngokuphelele izakhamzimba nama-enzyme e-pancreatic.

Izimo Zofuzo

ICystic fibrosis yisifo esizuzwe njengefa esidala ukuthi umzimba wenze ungqimba lwamafinyila obukhulu. Amafinyila abambelela emaphashini, ohlelweni lokugaya ukudla, nakwezinye izitho zomzimba. Cishe amaphesenti angama-90 abantu abane-cystic fibrosis baba ne-EPI.

I-Shwachman-Diamond syndrome yisimo esingajwayelekile, esizuzwe njengefa esithinta amathambo akho, umnkantsha kanye namanyikwe. Abantu abanalesi simo bavame ukuba ne-EPI besebancane. Umsebenzi wePancreatic uyathuthuka cishe engxenyeni yezingane njengoba zikhula.

Isifo seCeliac

Isifo seCeliac sihlotshaniswa nokungakwazi ukugaya i-gluten. Lesi sifo sithinta abantu abadala baseMelika. Kwesinye isikhathi, abantu abalandela ukudla okungenayo i-gluten basenezimpawu, njengohudo oluqhubekayo. Kulokhu, izimpawu zingabangelwa yi-EPI ehambisana nesifo seCeliac.

Umdlavuza wePancreatic

I-EPI iyinkinga yomdlavuza we-pancreatic. Inqubo yamangqamuzana omdlavuza eshintsha amaseli we-pancreatic ingaholela ku-EPI, futhi isimila singavimba ama-enzyme ukuthi angene endaweni yokugaya ukudla. I-EPI futhi iyinkinga yokuhlinzwa yokwelapha umdlavuza we-pancreatic.

Izifo Zamathumbu Okuvuvukala

Isifo sikaCrohn kanye nesilonda esidalwa yizilonda emathunjini zombili izifo zamathumbu ezivuthayo ezibangela ukuthi amasosha omzimba wakho ahlasele futhi avuthe umgudu wakho wokugaya ukudla. Abantu abaningi abanesifo sikaCrohn noma i-ulcerative colitis bangabuye bahlakulele i-EPI. Kodwa-ke, abacwaningi abakhombanga imbangela ngqo yalobu budlelwano.

IZollinger-Ellison Syndrome

Lesi yisifo esingajwayelekile lapho izimila kumanyikwe akho noma kwenye indawo esiswini sakho zenza inani elikhulu lamahomoni aholela ku-acid esiswini ngokweqile. Leyo asidi yesisu igcina ama-enzyme akho okugaya ukudla angasebenzi kahle, aholele ku-EPI.

Ngingavimbela i-EPI?

Izimo eziningi ezihlobene ne-EPI, kufaka phakathi umdlavuza we-pancreatic, i-cystic fibrosis, isifo sikashukela nomdlavuza we-pancreatic, azikwazi ukulawulwa.

Kepha kunezici ezithile ongazilawula. Ukusetshenziswa kotshwala ngamandla, okuqhubekayo kuyimbangela ejwayelekile kakhulu yokuqubuka kwamaphaphu. Ukuhlanganisa ukusetshenziswa kotshwala nokudla okunamafutha amaningi nokubhema kungakhuphula amathuba okuba ne-pancreatitis. Abantu abane-pancreatitis obangelwa ukusetshenziswa kotshwala obuningi bavame ukuba nobuhlungu besisu obukhulu kakhulu futhi bathuthukise i-EPI ngokushesha okukhulu.

I-cystic fibrosis noma i-pancreatitis esebenza emndenini wakho nayo yandisa amathuba akho okuba ne-EPI.