I-CBD Oyili Ye-Migraine: Ingabe Iyasebenza?
-Delile
- Okushiwo ucwaningo nge-CBD
- Funda nge-CBD ne-THC
- Olunye ucwaningo lwe-cannabis
- Izifundo ngensangu yezokwelapha
- Funda ku-nabilone
- Isebenza kanjani i-CBD
- Isetshenziswa kanjani i-CBD
- Imiphumela emibi engaba khona nezingozi
- Ngabe i-CBD izokuphakamisa?
- Ukuba semthethweni
- Khuluma nodokotela wakho
- I-3 Yoga Isusa Ukukhulula Ama-Migraines
Ukubuka konke
Ukuhlaselwa kwe-Migraine kudlulela ngaphezu kwengcindezi ejwayelekile- noma ikhanda elihlobene nokungezwani komzimba. Ukuhlaselwa kwe-Migraine kuhlala noma kuphi kusuka emahoreni amane kuya kwangu-72. Ngisho nemisebenzi ejwayelekile, njengokuhamba noma ukuba seduze komsindo nokukhanya, kungakhulisa izimpawu zakho.
Ngenkathi imithi yezinhlungu ingasiza ekunciphiseni okwesikhashana izimpawu zokuhlaselwa yi-migraine, ungahle ukhathazeke ngemiphumela yabo emibi. Yilapho i-cannabidiol (i-CBD) ingangena khona.
I-CBD ingenye yezakhi eziningi ezisebenzayo ezitholakala esitshalweni se-cannabis. Ikhule ngokuthandwa njengendlela yokwelapha ngokwemvelo izimo ezithile zezokwelapha.
Qhubeka ufunda ukuthola:
- uthini ucwaningo lwamanje ngokusebenzisa i-CBD ye-migraine
- isebenza kanjani
- imiphumela emibi engaba khona nokuningi
Okushiwo ucwaningo nge-CBD
Ucwaningo ngokusetshenziswa kwe-CBD ye-migraine lilinganiselwe. Izifundo ezikhona zibheka imiphumela ehlanganisiwe ye-CBD ne-tetrahydrocannabinol (THC), i-cannabinoid ehlukile. Okwamanje azikho izifundo ezishicilelwe ezihlola imiphumela ye-CBD njengesithako esisodwa ku-migraine.
Lolu cwaningo olunomkhawulo ludingeka, ngokwengxenye, kwimithethonqubo ye-CBD nezithiyo zokugunyazwa kwe-cannabis. Noma kunjalo, ezinye izifundo zelabhoratri ziphakamise ukuthi uwoyela we-CBD ungasiza zonke izinhlobo zobuhlungu obungapheli nobunzima, kufaka phakathi i-migraine.
Funda nge-CBD ne-THC
Ku-2017, ku-3rd Congress ye-European Academy of Neurology (EAN), iqembu labaphenyi lethule imiphumela yocwaningo lwabo ngama-cannabinoids nokuvimbela i-migraine.
Esigabeni I sesifundo sabo, abantu abangama-48 abane-migraine engapheli bathola inhlanganisela yamakhemikhali amabili. Isakhi esisodwa sasiqukethe amaphesenti ayi-19 we-THC, kanti esinye sasiqukethe i-9% ye-CBD futhi cishe ayikho i-THC. Amakhemikhali afakwa ngomlomo.
Imithamo engaphansi kwama-milligram ayi-100 (mg) ayizange ibe nomthelela. Lapho imithamo yenyuselwa ku-200 mg, ubuhlungu obukhulu bancishiswa ngamaphesenti angama-55.
Isigaba II sesifundo sibheke abantu abane-migraine engapheli noma ikhanda le-cluster. Abantu abangama-79 abane-migraine engapheli bathola isilinganiso sansuku zonke se-200 mg yenhlanganisela ye-THC-CBD kusuka esigabeni I noma i-25 mg ye-amitriptyline, i-tricyclic antidepressant.
Abantu abangama-48 abanekhanda le-cluster bathole isilinganiso sansuku zonke se-200 mg yenhlanganisela ye-THC-CBD kusuka esigabeni I noma ku-480 mg we-verapamil, i-calcium channel blocker.
Isikhathi sokwelashwa sithathe izinyanga ezintathu, futhi ukulandelwa kwenzeka emasontweni amane ngemuva kokuphela kokwelashwa.
Inhlanganisela ye-THC-CBD yehlise ukuhlaselwa kwe-migraine ngamaphesenti angama-40.4, ngenkathi i-amitriptyline iholele ekwehlisweni kwamaphesenti angama-40.1 ekuhlaselweni yi-migraine. Inhlanganisela ye-THC-CBD nayo inciphise ubukhulu bezinhlungu ngamaphesenti angama-43.5.
Ababambiqhaza abanekhanda le-cluster babone ukwehla okuncane ebukhulwini nasekuvameni kwamakhanda abo.
Kodwa-ke, abanye babone ubuhlungu babo behla ngamaphesenti angama-43.5. Lokhu kwehla kobukhulu bezinhlungu kwabonwa kuphela kubahlanganyeli ababenokuhlaselwa yi-migraine okwaqala ebuntwaneni.
Abaphenyi baphetha ngokuthi ama-cannabinoids ayesebenza kuphela ekulweni nekhanda elibuhlungu uma umuntu eke wahlaselwa yimigraine esemncane.
Olunye ucwaningo lwe-cannabis
Ukucwaninga ngezinye izinhlobo zensangu kunganikeza ithemba elengeziwe kulabo abafuna ukukhululeka kobuhlungu be-migraine.
Izifundo ngensangu yezokwelapha
Ngo-2016, i-Pharmacotherapy yashicilela isifundo ngokusetshenziswa kwensangu yezokwelapha ye-migraine. Abaphenyi bathola ukuthi kubantu abangama-48 okwaxoxwa nabo, amaphesenti angama-39.7 abike ukuhlaselwa okumbalwa kwe-migraine jikelele.
Ukozela bekuyisikhalazo esikhulu kunazo zonke, kanti abanye bebenobunzima bokuthola isilinganiso esifanele. Abantu abasebenzisa insangu edliwayo, ngokungafani nokuyihogela noma ukusebenzisa ezinye izinhlobo, bathole imiphumela emibi kakhulu.
Ucwaningo lwe-2018 lubheke abantu abangu-2,032 abane-migraine, ikhanda, i-arthritis, noma ubuhlungu obungapheli njengesibonakaliso esiyinhloko noma ukugula. Iningi labahlanganyeli likwazile ukufaka esikhundleni semithi yabo kadokotela - imvamisa ama-opioid noma ama-opiates - nge-cannabis.
Onke amaqenjana akhetha izinhlobo ze-cannabis ze-cannabis. Abantu abaseqenjini elincane le-migraine nekhanda bakhetha i-OG Shark, uhlobo lwe-hybrid olunamazinga aphezulu we-THC namazinga aphansi e-CBD.
Funda ku-nabilone
Ucwaningo lwase-Italy lwase-2012 luhlolisise imiphumela ye-nabilone, ifomu lokwenziwa le-THC, ekuphazamisekeni kwekhanda. Abantu abangamashumi amabili nesithupha abathola imishanguzo yokusebenzisa ikhanda ngokweqile baqala ngokuthatha imithamo yomlomo noma .50 mg ngosuku lwe-nabilone noma i-400 mg ngosuku lwe-ibuprofen.
Ngemuva kokuthatha umuthi owodwa amasonto ayisishiyagalombili, ababambiqhaza bocwaningo bahamba ngaphandle kwemithi isonto elilodwa. Ngemuva kwalokho bashintshela komunye umuthi amasonto ayisishiyagalombili okugcina.
Yomibili le mithi ikhombisile ukuthi iyasebenza. Kodwa-ke, ekupheleni kocwaningo, ababambiqhaza babike ukuthuthuka okuningi kanye nekhwalithi engcono yempilo lapho bethatha i-nabilone.
Ukusebenzisa i-nabilone kuholele ebuhlungwini obuncane kakhulu nasekunciphiseni ukuncika kwezidakamizwa. Asikho nesisodwa isidakamizwa esaba nomthelela omkhulu ekuvameni kokuhlaselwa yi-migraine, okucatshangwe abaphenyi ngesikhathi esifushane sesifundo.
Isebenza kanjani i-CBD
I-CBD isebenza ngokusebenzisana nama-receptors womzimba we-cannabinoid (CB1 ne-CB2). Yize izindlela zingaqondakali ngokuphelele, ama-receptors angathinta amasosha omzimba.
Isibonelo, i-CBD kungenzeka. I-anandamide eyinkimbinkimbi ihlotshaniswa nomthethonqubo wezinhlungu. Ukugcina amazinga aphezulu e-anandamide egazini lakho kunganciphisa imizwa yakho yobuhlungu.
I-CBD kucatshangwa nokuthi ikhawulela ukuvuvukala emzimbeni, okungasiza futhi ekunciphiseni ubuhlungu nezinye izimpendulo zamasosha omzimba.
Ucwaningo oluningi luyadingeka ukuze uqhubeke uqonde ukuthi i-CBD ingawuthinta kanjani umzimba.
Isetshenziswa kanjani i-CBD
Yize abomthetho e-United States njengamanje bephikisana ngokufaneleka kwensangu nemikhiqizo ehlobene nayo, ukusetshenziswa kwesitshalo okwelapha akuyona into entsha etholakele.
Ngokusho kwalokhu, insangu isetshenziswe kweminye imithi iminyaka engaphezu kuka-3 000. Okunye kwalokhu kusetshenziswa kufaka ukuphathwa kwe:
- ubuhlungu
- izimpawu zezinzwa
- ukuvuvukala
Uwoyela CBD kungaba:
- vaped
- kufakiwe
- kusetshenziswe ngokwezihloko
I-CBD yomlomo mancane amathuba okuthi ibangele imiphumela emibi kune-vaping, ngakho-ke abanye abaqalayo bangafuna ukuqala lapho. Ungakwazi:
- faka amaconsi ambalwa kawoyela ngaphansi kolimi lwakho
- thatha ama-capsules e-CBD
- udle noma uphuze umuthi ofakwe i-CBD
Uwoyela we-Vaping we-CBD ungazuzisa uma uhlangabezana ne-migraine enzima ekhaya futhi akudingeki uhambe futhi uye kwenye indawo.
Ichaza ukuthi inqubo yokuhogela iletha izinhlanganisela egazini lakho ngokushesha okukhulu kunezinye izindlela.
Njengamanje, azikho iziqondiso ezisemthethweni zokufakwa kwesilinganiso esifanele sokuhlaselwa kwe-migraine. Sebenza nodokotela wakho ukuthola isilinganiso esifanele.
Uma umusha kumafutha e-CBD, kufanele uqale ngomthamo omncane kakhulu ongaba khona. Ungasebenza kancane kancane uze ufike kumthamo ophelele onconyiwe. Lokhu kuzovumela umzimba wakho ukuthi ujwayele uwoyela futhi kunciphise ubungozi bemiphumela emibi.
Imiphumela emibi engaba khona nezingozi
Kukonke, ucwaningo lukhombisa ukuthi imiphumela emibi kawoyela we-CBD ne-CBD incane. Lesi ngesinye sezizathu eziyinhloko zokuthi kungani abantu bekhetha ukusebenzisa i-over-the-counter (i-OTC) noma imishanguzo yezinhlungu zemithi kadokotela.
Noma kunjalo, ukukhathala, ukozela, nesisu esibuhlungu kungenzeka, kanye nokushintsha kokudla nesisindo. Ubuthi besibindi buphinde babonwa kumagundane aphoqwe ngemithamo emikhulu ngokwedlulele yokukhishwa kwe-cannabis ecebile nge-CBD.
Ingozi yakho yemiphumela emibi ingaxhomeka endleleni osebenzisa ngayo uwoyela we-CBD. Isibonelo, ukuqhuma kungabangela ukucasuka kwamaphaphu. Lokhu kungaholela ku:
- ukukhwehlela okungapheli
- isifuba
- ubunzima bokuphefumula
Uma une-asthma noma olunye uhlobo lwesifo samaphaphu, udokotela wakho angakweluleka ngokufutha uwoyela we-CBD.
Uma ungaqiniseki ngemiphumela emibi engaba khona noma ukuthi umzimba wakho ungabhekana kanjani nayo, khuluma nodokotela wakho.
Uma futhi uthatha eminye imithi noma izithasiselo zokudla, khumbula ukuxhumana kwezidakamizwa. I-CBD ingaxhumana nezidakamizwa ezahlukahlukene, kufaka phakathi:
- ama-antibiotic
- imishanguzo
- abahlinza igazi
Qaphela ngokweqile uma uthatha umuthi noma isengezo esihlangana nesithelo samagilebhisi. I-CBD ne-grapefruit zombili ziyahlangana nama-enzyme - njenge-cytochromes P450 (CYPs) - abalulekile ekusetshenzisweni komzimba kwezidakamizwa.
Ngabe i-CBD izokuphakamisa?
Amafutha e-CBD enziwa nge-cannabis, kepha awanazo njalo i-THC. I-THC yi-cannabinoid eyenza abasebenzisi bazizwe "bephakeme" noma "bekhandwa ngamatshe" lapho bebhema insangu.
Izinhlobo ezimbili zamagciwane e-CBD zitholakala kabanzi emakethe:
- evelele
- ocebile
Uhlobo olunamandla lwe-CBD alunalutho lwe-THC, kanti uhlobo olucebile lwe-CBD luqukethe kokubili ama-cannabinoids.
I-CBD ngaphandle kwe-THC ayinazo izakhiwo ezingasebenzi.Noma ukhetha umkhiqizo ohlanganisiwe, i-CBD imelana nemiphumela ye-THC, ngokusho kwe-Project CBD engenzi nzuzo. Lesi ngesinye sezizathu eziningi ongakhetha uwoyela we-CBD kunensangu yezokwelapha.
Ingabe i-CBD isemthethweni? Imikhiqizo ye-CBD etholakala ngensangu ayikho emthethweni ezingeni likahulumeni, kodwa isemthethweni ngaphansi kweminye imithetho yezwe. Imikhiqizo ye-CBD eyenziwe nge-Hemp (engaphansi kwamaphesenti angu-0,3 iTHC) isemthethweni ezingeni likahulumeni, kepha namanje ayikho emthethweni ngaphansi kweminye imithetho yezwe. Hlola imithetho yesifundazwe sakho naleyo yanoma iyiphi indawo ohamba kuyo. Khumbula ukuthi imikhiqizo ye-CBD engabhalisiwe ayivunyelwe yi-FDA, futhi ingabhalwa ngokunganembile.
Ukuba semthethweni
Ngenxa yezakhi ezithinta ingqondo zensangu yendabuko, insangu isavinjelwe kwezinye izingxenye ze-United States.
Kodwa-ke, inani elikhulayo lamazwe livotele ukwamukela insangu yokusetshenziswa kwezokwelapha kuphela. Abanye babhalise insangu ngokusemthethweni ekusetshenzisweni kwezokwelapha nokungcebeleka.
Uma uhlala esifundeni lapho insangu isemthethweni khona ekwelapheni nasekuzilibaziseni, kufanele ube nokufinyelela kuwoyela we-CBD.
Kodwa-ke, uma izwe lakho livumele insangu ukusetshenziswa kwezokwelapha kuphela, kuzodingeka ufake isicelo sekhadi lensangu kudokotela wakho ngaphambi kokuthenga imikhiqizo ye-CBD. Le layisensi iyadingeka ekusetshenzisweni kwazo zonke izinhlobo zensangu, kufaka phakathi i-CBD.
Kwezinye izifundazwe, zonke izinhlobo zensangu azikho emthethweni. Ngokubambisana, insangu isabhekwa njengesidakamizwa esiyingozi futhi esingekho emthethweni.
Kubalulekile ukwazi imithetho esesifundazweni sakho kanye nanoma iziphi ezinye izifundazwe ongazivakashela. Uma imikhiqizo ehlobene nensangu ingekho emthethweni - noma uma idinga ilayisense yezokwelapha ongenayo - ungahle ube ngaphansi kwenhlawulo yokutholakala.
Khuluma nodokotela wakho
Ucwaningo oluningi luyadingeka ngaphambi kokuba uwoyela we-CBD ube yindlela yokwelashwa ejwayelekile ye-migraine, kodwa kufanelekile ukukhuluma nodokotela wakho uma unentshisekelo. Bangakweluleka ngomthamo ofanele kanye nanoma yiziphi izidingo zomthetho.
Uma uthatha isinqumo sokuzama uwoyela we-CBD, uphathe ngendlela ongathanda ngayo noma iyiphi enye indlela yokwelashwa ye-migraine. Kungathatha isikhathi ukusebenza, futhi ungahle udinge ukulungisa isilinganiso sakho ukuze sivumelane kangcono nezidingo zakho.
I-3 Yoga Isusa Ukukhulula Ama-Migraines
Ingabe i-CBD isemthethweni?Imikhiqizo ye-CBD eyenziwe nge-Hemp (engaphansi kwamaphesenti angu-0,3 iTHC) isemthethweni ezingeni likahulumeni, kepha namanje ayikho emthethweni ngaphansi kweminye imithetho yezwe. Imikhiqizo ye-CBD etholakala ngensangu ayikho emthethweni ezingeni likahulumeni, kodwa isemthethweni ngaphansi kweminye imithetho yezwe. Hlola imithetho yesifundazwe sakho naleyo yanoma iyiphi indawo ohamba kuyo. Khumbula ukuthi imikhiqizo ye-CBD engabhalisiwe ayivunyelwe yi-FDA, futhi ingabhalwa ngokunganembile.