Ipheshana le-chloramphenicol

-Delile

• Yenzelwe ini
• Ungathatha kanjani
• 1. Ukusetshenziswa ngomlomo noma ngomjovo
• 2. Ukusetshenziswa kwamehlo
• 3. Okhilimu namafutha okugcoba
• Imiphumela emibi engaba khona
• Ngubani ongafanele asebenzise

I-chloramphenicol iyimithi elwa namagciwane esetshenziselwa ukwelapha izifo ezahlukahlukene zamagciwane, njengalezo ezibangelwa amagciwane amancane I-Haemophilus influenzae, Salmonella tiphi futhi Ama-bacteriides fragilis.

Ukusebenza kwalo muthi kungenxa yokusebenza kwawo, okuqukethe ukuguqula amaprotheni synthesis wamagciwane, agcina ebuthaka futhi asuswe ngokuphelele emzimbeni womuntu.

I-chloramphenicol itholakala emakhemisi amakhulu, futhi itholakala ezethulweni ku-500mg tablet, 250mg capsule, 500mg pill, 4mg / mL and 5mg / ml ophthalmic solution, 1000mg injectable powder, syrup.

Yenzelwe ini

I-chloramphenicol inconyelwa ukwelashwa kwezifo ze-Haemophilus influenzae, njenge-meningitis, septicemia, otitis, pneumonia, epiglottitis, arthritis noma i-osteomyelitis.

Kubuye kuboniswe ekwelapheni umkhuhlane we-typhoid kanye ne-salmonellosis ehlaselayo, amathumba obuchopho ngu Ama-bacteriides fragilis nezinye izinto ezincane ezibucayi, i-bacterial meningitis ebangelwa I-Streptococcus noma I-Meningococcus, ezigulini ezingezwani ne-penicillin, izifo nge Pseudomonas pseudomallei, izifo zangaphakathi kwesisu, i-actinomycosis, i-anthrax, i-brucellosis, i-inguinal granuloma, i-treponematosis, isifo, i-sinusitis noma i-otitis engapheli.

Ungathatha kanjani

Ukusetshenziswa kweChloramphenicol kunconywa kanjena:

1. Ukusetshenziswa ngomlomo noma ngomjovo

Ukusetshenziswa kuvame ukuhlukaniswa ngamanani ama-4 noma ukuphathwa, njalo emahoreni ayisithupha. Kubantu abadala, umthamo ngu-50mg ngekhilogremu ngayinye ngesisindo ngosuku, ngomthamo ophakanyisiwe ophakanyisiwe ka-4g ngosuku. Kodwa-ke, kufanele kulandelwe izeluleko zezokwelapha, ngoba ezinye izifo ezinzima, ezifana ne-meningitis, zingafinyelela ku-100mg / kg / ngosuku.

Ezinganeni, umthamo walo muthi ubuye ube yi-50 mg ngekhilogremu yesisindo ngosuku, kepha ezinganeni ezisanda kuzalwa nezisanda kuzalwa ezingaphansi kwamasonto amabili ubudala, umthamo ungama-25 mg ngekhilogremu lesisindo ngosuku.

Kunconywa ukuthi umuthi uphuzwe esiswini esingenalutho, ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla.

2. Ukusetshenziswa kwamehlo

Ukwelashwa kwezifo zamehlo, kunconywa ukuthi usebenzise amathonsi ayi-1 noma ama-2 wesisombululo se-ophthalmic esweni elithintekile, njalo ngehora elilodwa noma amabili, noma ngokweseluleko sezokwelapha.

Kunconywa ukuthi ungathinti ichopho lebhodlela emehlweni, eminweni noma kwezinye izindawo, ukugwema ukungcoliswa ngumuthi.

3. Okhilimu namafutha okugcoba

I-chloramphenicol ingahlotshaniswa namafutha okuphulukisa noma ukwelapha izilonda ezitheleleke ngamagciwane azwelana nale antibiotic, njenge-collagenase noma i-fibrinase, ngokwesibonelo, futhi ijwayele ukusetshenziselwa ushintsho ngalunye lokugqoka noma kanye ngosuku. Funda kabanzi ngokusebenzisa i-Colagenase.

Imiphumela emibi engaba khona

Imiphumela emibi yeChloramphenicol ingaba: isicanucanu, isifo sohudo, i-enterocolitis, ukuhlanza, ukuvuvukala kwezindebe nolimi, izinguquko egazini, ukusabela kwe-hypersensitivity.

Ngubani ongafanele asebenzise

I-chloramphenicol iyaphikiswa ezigulini ezizwela kakhulu kunoma iyiphi ingxenye yefomula, kwabesifazane abakhulelwe noma abancelisayo, iziguli ezinomkhuhlane, umphimbo obuhlungu noma umkhuhlane.

Akufanele futhi isetshenziswe ngabantu abanezinguquko ezicutshini ezikhiqiza igazi, izinguquko enanini lamaseli egazi kanye neziguli ezinokungasebenzi kahle kwe-hepatic noma kwezinso.