Isifo Semithambo Ye-Collagen

-Delile

• Izimbangela zesifo semithambo ye-collagen
• Izimpawu zesifo semithambo ye-collagen
• Izimpawu ze-lupus
• Izimpawu zesifo samathambo
• Izimpawu ze-scleroderma
• Izimpawu ze-arteritis yesikhashana
• Ukwelashwa kwesifo semithambo yegazi i-collagen
• Ama-Corticosteroids
• Ama-immunosuppressants
• Ukwelashwa ngokomzimba
• Umbono wesikhathi eside

Isifo se-Collagen semithambo

"Isifo semithambo ye-Collagen" igama leqembu lezifo ezithinta izicubu zakho ezixhuma. I-Collagen izicubu ezixhumene namaprotheni ezakha uhlelo lokusekela isikhumba sakho. Izicubu ezixhumayo zigcina amathambo, imisipha nemisipha ndawonye. Isifo semithambo ye-Collagen kwesinye isikhathi sibizwa nangokuthi isifo sezicubu ezixhuma. Izifo zemithambo yegazi ye-Collagen zingazuzwa (zizuzwe njengefa kubazali bomuntu) noma ekuzilimeleni komzimba (okuvela ekusebenzeni kwamasosha omzimba okuzimele). Lo mbhalo ubhekene nezinhlobo ezizimele zezifo zemithambo yegazi i-collagen.

Ezinye izifo ezihlukaniswa njenge-collagen vascular disease zithinta amalunga akho, isikhumba, imithambo yegazi, noma ezinye izitho ezibalulekile. Izimpawu ziyahlukahluka ngokuya ngesifo esithile.

Izinhlobo ze-autoimmune collagen isifo semithambo zifaka:

• lupus
• isifo samathambo
• scleroderma
• i-arteritis yesikhashana

Izinhlobo zesifo sofuzo se-collagen zifaka:

• Isifo se-Ehlers-Danlos
• I-Marfan's syndrome
• I-Osteogenesis imperfecta (OI), noma isifo samathambo esibuhlungu

Izimbangela zesifo semithambo ye-collagen

Isifo semithambo yeCollagen yisifo esizimele. Lokhu kusho ukuthi amasosha akho omzimba ahlasela ngephutha izicubu zomzimba wakho ezinempilo. Akekho owaziyo ukuthi yini ebangela ukuthi amasosha omzimba wakho enze lokhu. Ukuhlaselwa kuvame ukudala ukuvuvukala. Uma unesifo semithambo ye-collagen, amasosha akho omzimba abangela ukuvuvukala ku-collagen yakho nasemalungeni aseduze.

Izifo eziningana ze-collagen vascular, kufaka phakathi i-lupus, scleroderma, ne-rheumatoid arthritis, zivame kakhulu kwabesifazane kunamadoda. Leli qembu lezifo livame ukuthinta abantu abadala abaseminyakeni engama-30 nengama-40. Izingane ezingaphansi kweminyaka engu-15 zingatholakala zine-lupus, kepha zithinta kakhulu abantu abadala kuneminyaka eyi-15.

Izimpawu zesifo semithambo ye-collagen

Uhlobo ngalunye lwesifo semithambo ye-collagen sinezimpawu zalo. Kodwa-ke, izinhlobo eziningi zesifo semithambo ye-collagen zabelana ngezimpawu ezifanayo ezifanayo. Abantu abane-collagen vascular disorders bavame ukuzwa:

• ukukhathala
• ubuthakathaka bemisipha
• imfiva
• Ubuhlungu bomzimba
• ubuhlungu obuhlangene
• ukuqubuka kwesikhumba

Izimpawu ze-lupus

I-Lupus yisifo se-collagen semithambo esidala izimpawu ezihlukile esigulini ngasinye. Izimpawu ezingeziwe zingabandakanya:

• ukuphelelwa umoya
• ubuhlungu besifuba
• ikhanda
• amehlo omile
• unhlangothi
• izilonda zomlomo
• ukuphuphuma kwesisu okuvela njalo

Abantu abane-lupus bangaba nezikhathi ezinde zokuxolelwa ngaphandle kwezimpawu. Izimpawu zingagqama ngezikhathi zokuxineka noma ngemuva kokuchayeka isikhathi eside elangeni.

Izimpawu zesifo samathambo

I-rheumatoid arthritis ithinta abantu abadala ababalelwa ezigidini eziyi-1.3 e-United States, ngokusho kweNational Institute of Arthritis and Musculoskeletal and Skin Diseases. Ukuvuvukala kwezicubu ezihlangene phakathi kwamalunga kubangela ubuhlungu nokuqina. Ungaba nezinkinga ezingapheli ngamehlo omile nomlomo owomile. Imithambo yakho yegazi noma ulwelwesi lwenhliziyo yakho lungavutha uma unale ndlela yesifo semithambo ye-collagen.

Izimpawu ze-scleroderma

I-Scleroderma yisifo se-autoimmune esingathinta i-:

• isikhumba
• inhliziyo
• amaphaphu
• umgudu wokugaya ukudla
• ezinye izitho

Izimpawu zihlanganisa ukuqina nokuqina kwesikhumba, ukuqubuka nezilonda ezivulekile. Isikhumba sakho singazizwa siqinile, kube sengathi siyelulwa, noma uzizwe unesigaxa ezindaweni. I-systemic scleroderma ingadala:

• ukukhwehlela
• isifuba
• ubunzima bokuphefumula
• isifo sohudo
• i-asidi ye-asidi
• ubuhlungu obuhlangene
• ukuba ndikindiki ezinyaweni zakho

Izimpawu ze-arteritis yesikhashana

I-arteritis yesikhashana, noma i-giant cell arteritis, ingenye indlela yesifo semithambo yegazi i-collagen. I-arteritis yesikhashana ukuvuvukala kwemithambo yegazi emikhulu, imvamisa leyo esekhanda. Izimpawu zivame kakhulu kubantu abadala abangaphezu kweminyaka engama-70 futhi zingafaka:

• ukuzwela kwekhanda
• ubuhlungu bomhlathi
• ikhanda
• ukulahleka kombono

Ukwelashwa kwesifo semithambo yegazi i-collagen

Ukwelashwa kwesifo semithambo ye-collagen kuyehluka kuya ngesimo sakho. Kodwa-ke, imishanguzo ye-corticosteroid kanye ne-immunosuppressant ivame ukwelapha izifo eziningi zezicubu.

Ama-Corticosteroids

ICorticosteroids inciphisa ukuvuvukala emzimbeni wakho wonke. Lesi sigaba semithi sisiza nokujwayela amasosha akho omzimba. I-Corticosteroids ingaba nemiphumela emibi kakhulu kwabanye abantu, kufaka phakathi ukuzuza kwesisindo nokushintsha kwemizwelo. Abanye abantu bangakhuphuka kushukela wegazi ngenkathi bethatha imishanguzo ye-corticosteroid.

Ama-immunosuppressants

Imithi ye-Immunosuppressant isebenza ngokwehlisa ukuphendula komzimba wakho. Uma impendulo yakho yokuzivikela komzimba iphansi, umzimba wakho ngeke uzihlasele ngokwawo njengangaphambili. Kodwa-ke, ukuvikeleka komzimba okuncane kungakhuphula nobungozi bokugula. Zivikele kumagciwane alula ngokuhlala kude nabantu abanemikhuhlane noma umkhuhlane.

Ukwelashwa ngokomzimba

Ukwelashwa ngokomzimba noma ukuzivocavoca ngomusa nakho kungelapha isifo se-collagen semithambo. Ububanzi bokuzivocavoca kokunyakaza kukusiza ukuthi ugcine ukuhamba kwakho futhi kunganciphisa ubuhlungu obuhlangene nobemisipha.

Umbono wesikhathi eside

Umbono wesifo semithambo ye-collagen uyahlukahluka kuye ngomuntu, futhi kuya ngesifo esithile. Kodwa-ke, kunento eyodwa efana ngayo: Zonke izifo ezizimele ziyizimo ezingapheli. Azinawo amakhambi, futhi kufanele uziphathe impilo yakho yonke.

Odokotela bakho bazosebenzisana nawe ukwakha uhlelo lokwelashwa oluzokusiza ukuphatha izimpawu zakho.