Siyini isifo seGestational Trophoblastic

-Delile

• Izinhlobo zesifo sokukhulelwa kwe-trophoblastic
• Ziyini izimpawu
• Izimbangela ezingaba khona
• Yini ukuxilongwa
• Yelashwa kanjani

Isifo se-Gestational trophoblastic, esaziwa nangokuthi i-hydatidiform mole, siyinkinga engajwayelekile, ebonakala ngokukhula okungajwayelekile kwama-trophoblast, angamaseli akhula ku-placenta futhi angadala izimpawu ezifana nobuhlungu besisu, ukopha kwesitho sangasese sowesifazane, isicanucanu nokuhlanza.

Lesi sifo singahlukaniswa sibe imvukuzane ephelele noma eyingxenye ye-hydatidiform, okuyisisulu esivame kakhulu, esihlaselayo, i-choriocarcinoma kanye nesimila se-trophoblastic.

Ngokuvamile, ukwelashwa kuqukethe ukuhlinzeka ukususa i-placenta nezicubu ku-endometrium, okufanele yenziwe ngokushesha okukhulu, ngoba lesi sifo singaholela ezinkingeni, njengokukhula komdlavuza.

Izinhlobo zesifo sokukhulelwa kwe-trophoblastic

Isifo se-Gestational trophoblastic sehlukaniswe saba:

• Qedela imvukuzane ye-hydatidiform, okuvame kakhulu futhi okuvela ekukhulelweni kweqanda elingenalutho, elingenayo i-nucleus ene-DNA, ngesidoda esingu-1 noma sesi-2, okunokuphindaphindeka okulandelanayo kwama-chromosomes kababa nokungabikho kokwakheka kwezicubu zomntwana, okuholela ukulahleka kwezicubu zombungu. umbungu nokwanda kwezicubu ze-trophoblastic;
• Ingxenye ye-hydatidiform mole, lapho iqanda elijwayelekile lifakwa khona isidoda esingu-2, nokwakheka kwezicubu zomzimba ezingavamile kanye nokukhipha isisu okuzenzakalelayo;
• Intwasahlobo ehlaselayo, engavamile kakhulu kunaleyo eyedlule futhi lapho kwenzeka khona ukuhlasela kwe-myometrium, okungadala ukuqhuma kwesibeletho futhi kuholele ekopha kakhulu;
• I-Choriocarcinoma, okuyisimila esihlaselayo nesine-metastatic, esakhiwe ngamangqamuzana abulalayo we-trophoblastic. Iningi lalezi zicubu zikhula ngemuva kwentwasahlobo ye-hydatidiform;
• Isigaxa se-trophoblastic sendawo ese-placental, okuyisigaxa esingavamile, esiqukethe amaseli we-trophoblastic aphakathi nendawo, aqhubeka ngemuva kokuphela kokukhulelwa, futhi angahlasela izicubu eziseduze noma enze ama-metastases.

Ziyini izimpawu

Izimpawu ezivame kakhulu ezingavela kubantu abanesifo sokukhulelwa i-trophoblastic isifo sokuphuma kwegazi esibomvu esinsundu phakathi ne-trimester yokuqala, isicanucanu nokuhlanza, ubuhlungu besisu, ukuxoshwa kwama-cysts esithweni sangasese, ukukhula okusheshayo kwesibeletho, ukwanda kwengcindezi yegazi, i-anemia, i-hyperthyroidism kanye ne-pre eclampsia.

Izimbangela ezingaba khona

Lesi sifo sibangelwa ukukhulelwa okungajwayelekile kweqanda elingenalutho, ngesidoda esisodwa noma ezimbili, noma ngeqanda elijwayelekile ngesidoda esingu-2, ngokuphindaphindeka kwala ma-chromosomes okudala iseli elingavamile, elizophindaphindeka.

Ngokuvamile, kunengozi enkulu yokuthola isifo sokukhulelwa kwabesifazane abangaphansi kweminyaka engama-20 noma ngaphezulu kwengama-35 noma kulabo asebeke bahlushwa yilesi sifo.

Yini ukuxilongwa

Ngokuvamile, ukuxilongwa kuqukethe ukwenza ukuhlolwa kwegazi ukuthola i-hCG hormone kanye ne-ultrasound, lapho kungenzeka khona ukuba khona kobukhona bama-cysts nokungabikho noma ukungajwayelekile ezicutshini zengane ne-amniotic fluid.

Yelashwa kanjani

Ukukhulelwa okungajwayelekile akusebenzi ngakho-ke kuyadingeka ukuthi kususwe i-placenta ukuvimbela izinkinga ezivela. Ngalokhu, udokotela angenza i-curettage, okuwukuhlinzwa lapho kususwa khona izicubu zesibeletho, egumbini lokuhlinzwa, ngemuva kokuphathwa kwe-anesthesia.

Kwezinye izimo, udokotela angancoma ngisho nokususa isibeletho, ikakhulukazi uma kunengozi yokuba nomdlavuza, uma umuntu engafuni ukuba nezingane eziningi.

Ngemuva kokwelashwa, umuntu kufanele ahambisane nodokotela futhi enze izivivinyo ezijwayelekile, isikhathi esingangonyaka, ukubona ukuthi ngabe zonke izicubu zisuswe kahle nokuthi ayikho ingozi yokuba nezinkinga.

Kungadingeka futhi ukwenza i-chemotherapy yesifo esiphikelelayo.