Ukuhlolwa kwe-CA 15.3 - kwenzelwa ini nokuthi kwenziwa kanjani

-Delile

• Yenzelwe ini
• Kwenziwa kanjani

Ukuhlolwa kwe-CA 15.3 ukuhlolwa okuvame ukucelwa ukuqapha ukwelashwa nokuhlola ukuphindeka komdlavuza webele. I-CA 15.3 yiprotheni evame ukukhiqizwa ngamangqamuzana amabele, noma kunjalo, kumdlavuza ukugxila kwale phrotheni kuphakeme impela, kusetshenziswa njengophawu lwesimila.

Yize isetshenziswa kabanzi kumdlavuza webele, i-CA 15.3 ingaphakanyiswa kwezinye izinhlobo zomdlavuza, njengephaphu, amanyikwe, i-ovary nesibindi, isibonelo. Ngakho-ke, kufanele i-odwe kanye nezinye izivivinyo, njengokuhlolwa kwamangqamuzana ukuhlola isakhi sofuzo somdlavuza webele nokuhlolwa okuhlola i-estrogen receptor, i-HER2. Bona ukuthi yikuphi ukuhlolwa okuqinisekisa nokuthola umdlavuza webele.

Yenzelwe ini

Ukuhlolwa kwe-CA 15.3 kusebenza kakhulu ukuhlola impendulo ekwelashweni komdlavuza webele nokuhlola ukuphindeka. Lokhu kuhlolwa akusetshenziselwa ukuhlolwa, njengoba kunokuzwela okuphansi nokucaciswa. Ngokuvamile kunconywa udokotela ukuthi enze lokhu kuhlolwa ngaphambi kokuqala ukwelashwa kanye namasonto ambalwa ngemuva kokuhlinzwa noma ukuqala i-chemotherapy, ukubheka ukuthi ngabe ukwelashwa kuyasebenza yini.

Ukuhlungwa kwaleli protheni egazini kukhuphuke kwabangu-10% besifazane esigabeni sokuqala somdlavuza webele nakubantu besifazane abangaphezu kwama-70% abanomdlavuza esigabeni esithuthuke kakhulu, imvamisa abane-metastasis, okukhonjiswa kakhulu ukwenza lokhu kuhlolwa abesifazane asebevele belashwa noma abelashwa umdlavuza.

Kwenziwa kanjani

Ukuhlolwa kwenziwa kuphela ngesampula segazi lomuntu futhi akudingi ukulungiswa. Igazi liyaqoqwa bese lithunyelwa elabhorethri ukuze licutshungulwe futhi lihlaziywe. Inqubo yokuhlaziya ngokuvamile iyazenzekela futhi idala imiphumela enembile nethembekile ngesikhathi esifushane.

Inani eliyisithenjwa lalesi sivivinyo lingu-0 kuye ku-30 ​​U / mL, amanani angaphezu kwalokhu asevele ekhombisa ubungozi. Ukuphakama kokuhlushwa kwe-CA 15.3 egazini, umdlavuza webele uthuthuke kakhulu. Ngaphezu kwalokho, ukwanda okuqhubekayo kokuhlushwa kwale protein kungakhombisa ukuthi lowo muntu akaphenduli ekwelashweni noma ukuthi amangqamuzana e-tumor ayanda futhi, okukhombisa ukubuyela emuva.

Ukugxila okuphezulu kwe-CA 15.3 akuhlali kukhombisa umdlavuza webele, njengoba le protein ingaphakanyiswa nakwezinye izinhlobo zomdlavuza, njenge-lung, umdlavuza we-ovari kanye nomdlavuza obala ngokobulili, ngokwesibonelo. Ngalesi sizathu, ukuhlolwa kwe-CA 15.3 akusetshenziselwa ukuhlolwa, kuphela ukuqapha lesi sifo.