I-Acromegaly ne-gigantism: izimpawu, izimbangela kanye nokwelashwa

-Delile

• Izimpawu eziyinhloko
• Yiziphi izinkinga
• Ungakuqinisekisa kanjani ukuxilongwa
• Yelashwa kanjani

I-Gigantism yisifo esingajwayelekile lapho umzimba ukhiqiza khona i-hormone yokukhula eyeqile, okuvame ukuthi kungenxa yokuba khona kwesimila esibi ku-pituitary gland, esaziwa nge-pituitary adenoma, senza ukuthi izitho nezitho zomzimba zikhule zibe zinkulu kunokujwayelekile.

Lapho lesi sifo sivela ekuzalweni, saziwa njenge-gigantism, kepha-ke, uma lesi sifo siqubuka ekubeni mdala, imvamisa sineminyaka engama-30 noma engama-50, saziwa njenge-acromegaly.

Kuzo zombili lezi zimo, lesi sifo sibangelwa ukushintsha kwendlala ye-pituitary, indawo yobuchopho ekhiqiza i-hormone yokukhula, ngakho-ke ukwelashwa kwenziwa ukunciphisa ukukhiqizwa kwamahomoni, okungenziwa ngokuhlinzwa., Ukusetshenziswa kwemithi noma imisebe, Ngokwesibonelo.

Izimpawu eziyinhloko

Abantu abadala abane-acromegaly noma izingane ezine-gigantism imvamisa banezandla ezinkulu, izinyawo nezindebe ezijwayelekile, kanye nobuso oburhabaxa. Ngaphezu kwalokho, ukukhula ngokweqile kwe-hormone nakho kungadala:

• Ukufaka noma ukushisa ezandleni nasezinyaweni;
• I-glucose eyeqile egazini;
• Ingcindezi ephezulu;
• Ubuhlungu nokuvuvukala emalungeni;
• Umbono ophindwe kabili;
• I-mandible ekhulisiwe;
• Shintsha ku-locomotion;
• Ukukhula kolimi;
• Ukuthomba sekwedlule isikhathi;
• Imijikelezo yokuya esikhathini engajwayelekile;
• Ukukhathala ngokweqile.

Ngaphezu kwalokho, njengoba kunethuba lokuthi i-hormone yokukhula ngokweqile ikhiqizwa isimila esibi ku-pituitary gland, ezinye izimpawu ezinjengekhanda elijwayelekile, izinkinga zombono noma ukwehla kwesifiso sobulili, ngokwesibonelo, nazo zingavela.

Yiziphi izinkinga

Ezinye zezinkinga ezingalethwa yilolu shintsho esigulini yilezi:

• Isifo sikashukela;
• I-apnea yokulala;
• Ukulahleka kombono;
• Ukukhulisa usayizi wenhliziyo;

Ngenxa yobungozi balezi zinkinga, kubalulekile ukuya kudokotela uma usola ukuthi lesi sifo noma ukukhula kuyashintsha.

Ungakuqinisekisa kanjani ukuxilongwa

Lapho kunokusola ngokuba ne-gigantism, kufanele kwenziwe ukuhlolwa kwegazi ukuze kuhlolwe amazinga e-IGF-1, iphrotheni elandiswayo lapho amazinga ama-hormone okukhula nawo engaphezulu kokujwayelekile, okukhombisa i-acromegaly noma i-gigantism.

Ngemuva kokuhlolwa, ikakhulukazi esimweni somuntu omdala, i-CT scan nayo inga-oda, ngokwesibonelo, ukukhomba ukuthi ngabe kukhona yini isimila endlaleni yebhinqa engashintsha umsebenzi waso. Kwezinye izimo, udokotela anga-oda ukukalwa kokugxila kwe-hormone yokukhula.

Yelashwa kanjani

Ukwelashwa kwe-gigantism kuyehluka kuye ngokuthi yini ebanga i-hormone yokukhula eyeqile. Ngakho-ke, uma kukhona isimila endlaleni yesibeletho, kuvame ukunconywa ukuthi kwenziwe ukuhlinzwa ukuze kususwe isimila futhi kubuyiselwe ukukhiqizwa okufanele kwamahomoni.

Kodwa-ke, uma singekho isizathu sokuthi umsebenzi we-pituitary ushintshe noma uma ukuhlinzwa kungasebenzi, udokotela angakhombisa kuphela ukusetshenziswa kwemisebe noma imishanguzo, njenge-somatostatin analogs noma i-dopamine agonists, ngokwesibonelo, okufanele isetshenziswe ngesikhathi sokuphila konke ukugcina amazinga e-hormone elawulwa.