Ukuhlolwa kweGlobulin
-Delile
- Kuyini ukuhlolwa kweglobulin?
- Kusetshenziselwa ini?
- Kungani ngidinga ukuhlolwa kweglobulin?
- Kwenzekani ngesikhathi sokuhlolwa kweglobulin?
- Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
- Ingabe zikhona izingozi esivivinyweni?
- Isho ukuthini imiphumela?
- Izinkomba
Kuyini ukuhlolwa kweglobulin?
Ama-globulin yiqembu lamaprotheni egazini lakho. Zenziwa esibindini sakho amasosha akho omzimba. Ama-globulin adlala indima ebalulekile ekusebenzeni kwesibindi, ekunqandeni igazi nasekulweni nokutheleleka. Kunezinhlobo ezine eziyinhloko zama-globulin. Babizwa ngokuthi i-alpha 1, i-alpha 2, i-beta, ne-gamma. Njengoba nje kunezinhlobo ezahlukahlukene zama-globulin, kunezinhlobo ezahlukahlukene zokuhlolwa kwe-globulin. Lokhu kufaka phakathi:
- Ukuhlolwa okuphelele kwamaprotheni. Lokhu kuhlolwa kwegazi kukala izinhlobo ezimbili zamaprotheni: i-globulin ne-albhamuin. Uma amazinga amaprotheni ephansi, kungasho ukuthi unesifo sesibindi noma sezinso.
- I-Serum protein electrophoresis. Lokhu kuhlolwa kwegazi kukala ama-gamma globulins namanye amaprotheni egazini lakho. Ingasetshenziselwa ukuxilonga izimo ezahlukahlukene, kufaka phakathi ukuphazamiseka kwamasosha omzimba kanye nohlobo lomdlavuza olubizwa nge-multiple myeloma.
Amanye amagama wokuhlolwa kwe-globulin: I-Serum globulin electrophoresis, inani lamaprotheni
Kusetshenziselwa ini?
Ukuhlolwa kwe-Globulin kungasetshenziswa ukuxilonga izimo ezahlukahlukene, kufaka phakathi:
- Ukulimala kwesibindi noma izifo
- Isifo sezinso
- Izinkinga zokudla okunempilo
- Ukuphazamiseka okuzenzakalelayo
- Izinhlobo ezithile zomdlavuza
Kungani ngidinga ukuhlolwa kweglobulin?
Umhlinzeki wakho wezokunakekelwa kwempilo anga-oda ukuhlolwa kwe-globulin njengengxenye yokuhlolwa kwakho okuvamile noma ukusiza ukuthola izimo ezithile. Ukuhlolwa okuphelele kwamaprotheni kungafakwa ochungechungeni lwezivivinyo zokubheka ukuthi isibindi sakho sisebenza kahle kangakanani. Lezi zivivinyo, ezibizwa ngokuthi izivivinyo zomsebenzi wesibindi, zinga-oda uma usengozini yesifo sesibindi noma unezimpawu zesifo sesibindi, ezingafaka:
- I-jaundice, isimo esidala ukuthi isikhumba namehlo akho abe phuzi
- Isicanucanu nokuhlanza
- Ukulunywa
- Ukukhathala okuqhubekayo
- Ukwakhela uketshezi esiswini, ezinyaweni, nasemilenzeni
- Ukuphelelwa isifiso sokudla
Isivivinyo se-serum protein electrophoresis silinganisa i-gamma globulins namanye amaprotheni. Lokhu kuhlolwa kungalawulwa ukuthi kuhlolwe ukuphazamiseka okuhlobene namasosha omzimba, kufaka phakathi:
- Ukungezwani komzimba
- Izifo ezizenzakalelayo njenge-lupus ne-rheumatoid arthritis
- I-myeloma eminingi, uhlobo lomdlavuza
Kwenzekani ngesikhathi sokuhlolwa kweglobulin?
Ukuhlolwa kweglobulin ukuhlolwa kwegazi. Ngesikhathi sokuhlolwa kwegazi, uchwepheshe wezokunakekelwa kwempilo uzothatha isampuli yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.
Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
Awudingi noma yimaphi amalungiselelo akhethekile okuhlolwa kwe-globulin. Uma umhlinzeki wakho wezokunakekelwa kwempilo naye eyalele okunye ukuhlolwa kwegazi, kungadingeka ukuthi uzile ukudla (ungadli noma uphuze) amahora ambalwa ngaphambi kokuhlolwa. Umhlinzeki wakho wezokunakekelwa kwempilo uzokwazisa uma ngabe kukhona imiyalelo ekhethekile ongayilandela.
Ingabe zikhona izingozi esivivinyweni?
Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.
Isho ukuthini imiphumela?
Izinga eliphansi le-globulin kungaba uphawu lwesifo sesibindi noma sezinso. Amazinga aphezulu angabonisa ukutheleleka, isifo sokuvuvukala noma ukuphazamiseka komzimba. Amazinga aphezulu e-globulin angakhombisa nezinhlobo ezithile zomdlavuza, njenge-myeloma eminingi, isifo sikaHodgkin, noma i-malignant lymphoma. Kodwa-ke, imiphumela engajwayelekile ingahle ibangelwe yimithi ethile, ukwehla emzimbeni, noma ezinye izinto. Ukuze ufunde ukuthi imiphumela yakho isho ukuthini, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.
Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.
Izinkomba
- I-AIDSinfo [i-Intanethi]. UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. IGamma Globulin; [kubuyekezwe 2017 Feb 2; kukhonjiwe ngo-2017 Feb 2]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://aidsinfo.nih.gov/education-materials/glossary/261/gamma-globulin
- I-American Cancer Society [Inthanethi]. I-Atlanta: I-American Cancer Society Inc.; c2017. Yini i-myeloma eminingi ?; [kubuyekezwe 2016 Jan 19; kukhonjiwe ngo-2017 Feb 2]; [cishe izikrini ezi-2]. Kutholakala kusuka: http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-what-is-multiple-myeloma
- I-American Liver Foundation. [Inthanethi]. ENew York: I-American Liver Foundation; c2017. Ukuhlolwa Komsebenzi Wesibindi; [kubuyekezwe 2016 Jan 25; kukhonjiwe ngo-2017 Feb 2]; [cishe izikrini ezi-4]. Kutholakala kusuka: http://www.liverfoundation.org/abouttheliver/info/liverfunctiontests/
- I-Immune Defence Foundation [i-Intanethi]. I-Towson (MD): Isisekelo sokushoda komzimba c2016. Ukushoda kwe-IgA okukhethiwe [okushiwo ngo-2017 Feb 2]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://primaryimmune.org/about-primary-immunodeficiencies/specific-disease-types/selective-iga-deficiency/
- Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2017. Ingqikithi Yamaphrotheni kanye ne-Albumin / Globulin (A / G) Isilinganiselo; [kubuyekezwe i-2016; Ephreli 10; kukhonjiwe ngo-2017 Feb 2]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/understanding/analytes/tp/tab/test/
- UMcCallen C, Axel A, Slaets D, Dejoie T, Clemens P, Frans S, Bald J, Plesner T, Jacobs J, van de Donk N, Schecter J, Ahmadi T Sasser, A. Ukuqapha iziguli eziningi ze-myeloma eziphathwe nge-daratumumab: ukugconwa ukuphazanyiswa kwe-antibody monoclonal. I-Clinical Chemistry neLaboratory Medicine (CCLM) [i-Intanethi]. I-2016 Jun [icashunwe ngo-2017 Feb 2]; 54 (6). Kutholakala kusuka: https://www.degruyter.com/view/j/cclm.2016.54.issue-6/cclm-2015-1031/cclm-2015-1031.xml
- I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ziyini Izingozi Zokuhlolwa Kwegazi ?; [kubuyekezwe 2012 Jan 6; kukhonjiwe ngo-2017 Feb 2]; [cishe izikrini ezi-5]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
- I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ongakulindela Nezivivinyo Zegazi; [kubuyekezwe 2012 Jan 6; kukhonjiwe ngo-2017 Feb 2]; [cishe izikrini ezi-5]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
- U-O'Connell T, uHorita T, uKasravi B. Ukuqonda nokutolika iSerum Protein Electrophoresis. Udokotela Womndeni waseMelika [i-Intanethi]. 2005 Jan 1 [icashunwe ngo-2017 Feb 2]; 71 (1): 105–112. Kutholakala kusuka: http://www.aafp.org/afp/2005/0101/p105.html
- Isikhungo iJohns Hopkins Lupus [Internet]. UJohn Hopkins Medicine; c2017. Iphaneli Legazi Chemistry [icashunwe ngo-2017 Feb 2]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://www.hopkinslupus.org/lupus-tests/screening-laboratory-tests/blood-chemistry-panel/
- Impilo ye-UF: University of Florida Health [Internet]. Inyuvesi yaseFlorida; c2017. I-serum globulin electrophoresis; [kucashunwe ngo-2017 Feb 2]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/serum-globulin-electrophoresis
- I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: Amaprotheni Electrophoresis (Igazi); [kucashunwe ngo-2017 Feb 2]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=protein_electrophoresis_serum
- I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: Amaprotheni aphelele ne-A / G Ratio; [kucashunwe ngo-2017 Feb 2]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=total_protein_ag_ratio
Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.