Izimbangela Zegciwane

-Delile

• Ukwehla kokukhishwa kwe-uric acid
• Ukukhiqizwa okwandisiwe kwe-uric acid
• Ukudla okuphezulu kuma-purines
• Izici zobungozi
• Iminyaka nobulili
• Umlando womndeni
• Imithi
• Ukusetshenziswa kotshwala
• Ukuvezwa kokuhola
• Ezinye izimo zempilo
• Izimbangela ze-Gout
• Umbono

Ukubuka konke

I-Gout ibangelwa ukwakheka kwama-urate crystals ezicutshini zomzimba. Imvamisa kwenzeka emajoyintini noma aseduze futhi kuholele kuhlobo olubuhlungu lwe-arthritis.

Amakristalu e-urate afakwa ezicutshini lapho kune-uric acid eningi egazini. Leli khemikhali lenziwa lapho umzimba wephula izinto ezaziwa ngokuthi ama-purines. I-uric acid eningi egazini yaziwa nangokuthi yi-hyperuricemia.

I-Gout ingabangelwa ukwehla kokukhishwa kwe-uric acid, ukukhiqizwa okwandisiwe kwe-uric acid, noma ukudla okuphezulu okudliwayo kwama-purines.

Ukwehla kokukhishwa kwe-uric acid

Ukwehla kokuncipha kwe-uric acid kuyimbangela evame kakhulu yegout. I-uric acid ivame ukususwa emzimbeni wakho izinso zakho. Uma lokhu kungenzeki kahle, izinga lakho le-uric acid liyakhula.

Imbangela ingahle ibe ngofuzo, noma ungaba nezinkinga zezinso ezikwenza ungakwazi ukususa i-uric acid.

Ubuthi bomthofu kanye nezidakamizwa ezithile, njenge-diuretics kanye nemithi yokuzivikela emzimbeni, kungadala ukulimala kwezinso okungaholela ekugcinweni kwe-uric acid. Isifo sikashukela esingalawulwa kanye nomfutho wegazi ophakeme nakho kunganciphisa ukusebenza kwezinso.

Ukukhiqizwa okwandisiwe kwe-uric acid

Ukukhuphuka komkhiqizo we-uric acid nakho kungadala igawuthi. Ezimweni eziningi, imbangela yokwanda kokukhiqizwa kwe-uric acid ayaziwa. Kungabangelwa ukungajwayelekile kwe-enzyme futhi kungenzeka ezimweni ezibandakanya:

• I-lymphoma
• i-leukemia
• i-hemolytic anemia
• ukhwekhwe

Kungenzeka futhi ukuthi kube nomphumela ohlangothini we-chemotherapy noma i-radiation therapy, ngenxa yokungajwayelekile kwefa, noma ngenxa yokukhuluphala.

Ukudla okuphezulu kuma-purines

Ama-purines ayizingxenye zamakhemikhali zemvelo ze-DNA ne-RNA. Lapho umzimba wakho uwaphula, aphenduka abe yi-uric acid. Amanye ama-purine atholakala ngokwemvelo emzimbeni. Kodwa-ke, ukudla okunama-purine amaningi kungaholela ku-gout.

Okunye ukudla kuphezulu kakhulu kuma-purine futhi kungakhuphula amazinga e-uric acid egazini. Lokhu kudla okune-purine ephezulu kufaka phakathi:

• inyama yomzimba, efana nezinso, isibindi, nama-sweetbreads
• inyama ebomvu
• izinhlanzi ezinamafutha, njengosardini, ama-anchovies ne-herring
• imifino ethile, kufaka phakathi i-asparagus ne-cauliflower
• ubhontshisi
• amakhowe

Izici zobungozi

Ezimweni eziningi, imbangela ngqo ye-gout noma i-hyperuricemia ayaziwa. Odokotela bakholelwa ukuthi kungenzeka kungenxa yenhlanganisela yezakhi zofuzo, i-hormonal, noma izinto ezidliwayo. Kwezinye izimo, ukwelashwa kwezidakamizwa noma izimo ezithile zezokwelapha nakho kungadala izimpawu ze-gout.

Iminyaka nobulili

Abesilisa banamathuba amaningi kunabesifazane okuba nezimpawu zokugula. Iningi labesilisa litholakala lineminyaka ephakathi kwengama-30 nengama-50 ubudala. Kwabesifazane, lesi sifo sidlange kakhulu ngemuva kokunqamuka kokuya esikhathini.

I-Gout ayivamile ezinganeni nakubantu abadala abasebasha.

Umlando womndeni

Abantu abanezihlobo zegazi abane-gout maningi amathuba okuthi nabo batholakale benale nkinga.

Imithi

Kunemithi eminingana engakhuphula ubungozi bokuhlaselwa yi-gout. Lokhu kufaka phakathi:

• I-aspirin yedosi ephansi yansuku zonke. I-aspirin enomthamo ophansi ijwayele ukusetshenziselwa ukuvimbela isifo senhliziyo nokushaywa unhlangothi.
• I-Thiazide isisu. Le mithi isetshenziselwa ukwelapha umfutho wegazi ophakeme, ukwehluleka kwenhliziyo okucinana (CHF), nezinye izimo.
• Izidakamizwa ze-Immunosuppressant. Izidakamizwa ze-Immunosuppressant, njenge-cyclosporine (Neoral, Sandimmune), zithathwa ngemuva kokufakelwa kwezitho zomzimba kanye nezimo ezithile ze-rheumatologic.
• I-Levodopa (iSinemet). Lokhu ukwelashwa okuthandwayo kwabantu abanesifo sikaParkinson.
• I-Niacin. Eyaziwa nangokuthi i-vitamin B-3, i-niacin isetshenziselwa ukwandisa ama-lipoprotein aphezulu (HDL) egazini.

Ukusetshenziswa kotshwala

Ukulingene ekuphuzeni ngokweqile kwandisa ubungozi bokuguliswa. Lokhu ngokuvamile kusho iziphuzo ezingaphezu kwezimbili ngosuku kwabesilisa abaningi noma eyodwa ngosuku kubo bonke abesifazane noma amanye amadoda angaphezu kweminyaka engama-65.

Ikakhulukazi ubhiya ubandakanyekile, futhi isiphuzo siphezulu kuma-purine. Kodwa-ke, ucwaningo lwango-2014 luqinisekise ukuthi iwayini, ubhiya, notshwala konke kungadala ukuhlaselwa kwe-gout okuphindaphindiwe. Funda kabanzi ngobudlelwano phakathi kotshwala ne-gout.

Ukuvezwa kokuhola

Ukuvezwa emazingeni aphezulu okuhola nakho kuhlotshaniswa ne-gout.

Ezinye izimo zempilo

Abantu abanezifo nemibandela elandelayo kungenzeka babe ne-gout:

• ukukhuluphala ngokweqile
• isifo sikashukela
• umfutho wegazi ophakeme
• cholesterol ephezulu
• i-hypothyroidism
• isifo sezinso
• i-hemolytic anemia
• ukhwekhwe

Izimbangela ze-Gout

Ezinye izinto ezingadala ukuhlaselwa yi-gout zifaka:

• ukulimala ngokuhlanganyela
• ukutheleleka
• ukuhlinzwa
• izidlo zokuphahlazeka
• ukwehlisa ngokushesha amazinga e-uric acid ngemithi
• ukoma komzimba

Umbono

Unganciphisa amathuba akho okuthuthukisa i-gout ngokubuka ukuphuza kwakho utshwala nokudla ukudla okuphansi kuma-purines. Ezinye izimbangela ze-gout, njengokulimala kwezinso noma umlando womndeni, azikwazi ukumelana nazo.

Khuluma nodokotela wakho uma ukhathazekile ngamathuba akho okuthuthukisa i-gout.

Bangakwazi ukuza nohlelo lokunciphisa amathuba akho okuthuthukisa lesi simo. Isibonelo, uma unezinto ezinobungozi bokutholwa yi-gout (njengesimo esithile sezokwelapha), bangakucabanga lokho ngaphambi kokuncoma izinhlobo ezithile zemithi.

Kodwa-ke, uma uthola i-gout, qiniseka ukuthi isimo singalawulwa ngenhlanganisela yemithi, ushintsho ekudleni, nakwamanye amakhambi.