Yini i-Wegener's granulomatosis nokuthi ungayelapha kanjani
-Delile
- Izimpawu eziyinhloko
- Indlela yokwelapha
- Ukuxilongwa kwenziwa kanjani
- Yini ebangela i-Wegener's granulomatosis
I-Wegener's granulomatosis, eyaziwa nangokuthi i-granulomatosis ene-polyangiitis, isifo esingajwayelekile futhi esiqhubekayo esidala ukuvuvukala emithanjeni yegazi ezingxenyeni ezahlukahlukene zomzimba, okudala izimpawu ezifana nokuminyana komoya, ukuphefumula, izilonda zesikhumba, ukuphuma kwegazi, ukuvuvukala ezindlebeni, umkhuhlane , ukugula, ukungathandi ukudla noma ukucasuka kweso.
Njengoba kuyisifo esidalwa yizinguquko ezenzeka emzimbeni, ukwelashwa kwaso kwenziwa ikakhulukazi ngemithi yokulawula uhlelo lwama-inume, njenge-corticosteroids kanye ne-immunosuppressants, futhi yize lungekho ikhambi, lesi sifo ngokuvamile silawulwa kahle, sivumela impilo ejwayelekile.
I-Wegener's granulomatosis iyingxenye yeqembu lezifo ezibizwa nge-vasculitis, elibonakala ngokudala ukuvuvukala nokulimala emithanjeni yegazi, engaphazamisa ukusebenza kwezitho ezahlukahlukene. Ukuqonda kangcono izinhlobo ze-vasculitis ezikhona nokuthi ungazikhomba kanjani.
Izimpawu eziyinhloko
Ezinye zezimpawu ezinkulu ezibangelwa yilesi sifo zifaka:
- I-sinusitis ne-noseleeds;
- Ukukhwehlela, ubuhlungu besifuba nokuphefumula okuncane;
- Ukwakheka kwezilonda ku-mucosa yekhala, okungaholela ekukhubazekeni okwaziwayo ngamakhala esihlalo;
- Ukuvuvukala ezindlebeni;
- I-conjunctivitis nokunye ukuvuvukala emehlweni;
- Imfiva nobusuku ukujuluka;
- Ukukhathala nokukhathala;
- Ukwehla kwesifiso sokudla nokuncipha;
- Ubuhlungu obuhlangene nokuvuvukala emajoyintini;
- Ubukhona begazi emchameni.
Ezimweni ezingavamile, kungahle kube nokukhubazeka kwenhliziyo, okuholele ekungenweni yi-pericarditis noma izilonda emithanjeni ye-coronary, noma nakuhlelo lwezinzwa, okuholela ezimpawu zezinzwa.
Ngaphezu kwalokho, iziguli ezinalesi sifo zinomkhuba owandayo wokuthuthukisa i-thrombosis, futhi kufanele kunakwe izimpawu ezibonisa le nkinga, njengokuvuvukala nokubomvu emilenzeni.
Indlela yokwelapha
Ukwelashwa kwalesi sifo kubandakanya ukusetshenziswa kwemithi esiza ukulawula amasosha omzimba, njengeMethylprednisolone, Prednisolone, Cyclophosphamide, Methotrexate, Rituximab noma izindlela zokwelapha zebhayoloji.
I-antibiotic sulfamethoxazole-trimethoprim ingahlotshaniswa nokwelashwa njengendlela yokunciphisa ukubuyela emuva kwezinye izinhlobo zezifo.
Ukuxilongwa kwenziwa kanjani
Ukuze kuhlolwe i-granulomatosis ka-Wegen, udokotela uzohlola izimpawu ezilethwayo kanye nokuhlolwa komzimba, okunganikeza izimpawu zokuqala.
Ngemuva kwalokho, ukuqinisekisa ukuxilongwa, ukuhlolwa okuyinhloko ukwenza i-biopsy yezicubu ezithintekile, okukhombisa ushintsho oluhambisana ne-vasculitis noma i-necrotizing granulomatous inflammation. Ukuhlolwa kungabuye ku-odwe, njengokulinganisa kwe-antibody ye-ANCA.
Ngaphezu kwalokho, kubalulekile ukuthi udokotela ahlukanise lesi sifo nakwabanye esingaba nezimpawu ezifanayo, njengomdlavuza wamaphaphu, i-lymphoma, ukusetshenziswa kwe-cocaine noma i-lymphomatoid granulomatosis, isibonelo.
Yini ebangela i-Wegener's granulomatosis
Izimbangela eziqondile eziholela ekuqaleni kwalesi sifo azaziwa, noma kunjalo, kuyaziwa ukuthi kuhlobene nezinguquko ekuphenduleni komzimba, okungaba izingxenye zomzimba uqobo noma izinto zangaphandle ezingena emzimbeni.