Ukuthethelelwa kwe-Hepatitis C

-Delile

• Kusho ukuthini i-SVR
• I-Hepatitis C ingazicacela yodwa
• Iphathwa kanjani i-hepatitis C
• Izici ezibikezela impendulo yakho ekwelashweni
• Ukuphindaphinda kwe-Hepatitis C
• Qeda njalo imithi yakho

Ukuxolelwa kwe-Hepatitis C kungenzeka

Phakathi kwabantu emhlabeni wonke, kufaka phakathi isilinganiso, bane-hepatitis C. engalapheki Igciwane lisakazeka ikakhulu ngokusebenzisa umjovo wezidakamizwa. Ukungalashwa kwesifo sofuba C kungaholela ezinkingeni ezinkulu zesibindi, kufaka phakathi i-cirrhosis nomdlavuza.

Izindaba ezimnandi ukuthi igciwane lingangena ekuxolelweni ngokwelashwa okulungile. Odokotela babhekisa ekuxolelweni njengempendulo eqhubekayo yamagciwane (SVR).

Kusho ukuthini i-SVR

I-SVR isho ukuthi igciwane le-hepatitis C alikwazi ukutholwa egazini lakho emavikini ayi-12 ngemuva komthamo wakho wokugcina wokwelashwa. Ngemuva kwalokhu, kungenzeka kakhulu ukuthi igciwane lihambe unomphela. Umnyango Wezilwane Zase-U.S. WaseMelika ubika ukuthi amaphesenti angama-99 abantu abazuze i-SVR bahlala bengenalo igciwane.

Laba bantu futhi:

• ukuthuthukiswa kwesipiliyoni ekuvukeleni kwesibindi
• yehle noma yabuyisa i-fibrosis
• kunamathuba aphindwe kabili okuba nezikolo zokuvuvukala eziphansi
• zinciphise ingozi yokufa, ukwehluleka kwesibindi nomdlavuza wesibindi
• anciphise amathuba abo okuthuthukisa ezinye izimo zezokwelapha

Ngokuya ngokulimala kwesibindi, uzodinga ama-aphoyintimenti okulandelela nokuhlolwa kwegazi njalo ezinyangeni eziyisithupha noma eziyishumi nambili. I-antibody ye-hepatitis C izoba nethemba laphakade, kepha lokhu akusho ukuthi usuthelelekile futhi.

I-Hepatitis C ingazicacela yodwa

Kwabanye abantu, i-hepatitis C nayo ingazicacela yodwa. Lokhu kubizwa ngokuthi ukuxolelwa okuzenzakalelayo. Izinsana nabesifazane abasebancane ikakhulukazi bangaba nethuba lokuthi igciwane lizisule emzimbeni wabo. Lokhu kuncane kakhulu phakathi kweziguli ezindala.

Ukutheleleka okunamandla (okungaphansi kwezinyanga eziyisithupha ubude) kuxazululwa ngokuzenzekelayo kumaphesenti ayi-15 kuye kwangama-50 amacala. Ukuxolelwa okuzenzakalelayo kwenzeka ngaphansi kwamaphesenti ama-5 wezifo ezingama-hepatitis C ezingamahlalakhona.

Iphathwa kanjani i-hepatitis C

Ukwelashwa kwezidakamizwa kungasiza amathuba akho okushaya igciwane le-hepatitis C ekuxolelweni. Uhlelo lwakho lokwelashwa luzoya ngalokhu:

• Uhlobo: Uhlobo lwakho lwe-hepatitis C genotype noma "ipulani" yegciwane kusekelwe ekulandeleni kwakho kwe-RNA. Kunezakhi zofuzo eziyisithupha. Cishe amaphesenti angama-75 abantu base-United States bane-genotype 1.
• Ukulimala kwesibindi: Ukulimala kwesibindi okukhona, noma ngabe kumnene noma kubi kakhulu, kungacacisa imithi yakho.
• Ukwelashwa kwangaphambilini: Imiphi imishanguzo osuyithathile nayo izothonya izinyathelo ezilandelayo.
• Ezinye izimo zezempilo: I-coinfection ingavimbela izidakamizwa ezithile.

Ngemuva kokubheka lezi zinto, umhlinzeki wakho wezokunakekelwa kwempilo uzokunikeza inkambo yemithi oyiphuzayo amasonto ayi-12 noma angama-24. Ungadinga ukuthatha le mithi isikhathi eside. Izidakamizwa ze-hepatitis C zingafaka:

• i-daclatasvir (Daklinza) ne-sofosbuvir (Sovaldi)
• i-sofosbuvir ene-velpatasvir (i-Epclusa)
• ledipasvir / sofosbuvir (Harvoni)
• simeprevir (Olysio)
• i-boceprevir (Victrelis)
• lindokuhle
• i-ribavirin (Ribatab)

Ungase uzwe ezinye zezidakamizwa ezintsha ezibizwa ngokuthi yimithi yokulwa namagciwane esebenza ngqo (DAA). Lokhu kuphindaphindwa kwegciwane okuqondisiwe ezinyathelweni ezithile zomjikelezo wokuphila we-hepatitis C.

Udokotela wakho angakunikeza ezinye izinhlanganisela zale mithi. Ungahlala wazi ngezokwelapha ze-hepatitis C ngokubuza udokotela wakho noma ngokuvakashela i-HEP C123. Hlala ulandela futhi uqeda imishanguzo yakho. Ukwenza kanjalo kwandisa amathuba akho okuxolelwa.

Izici ezibikezela impendulo yakho ekwelashweni

Izici eziningana zingasiza ukubikezela impendulo yakho ekwelashweni. Lokhu kufaka phakathi:

• Umjaho: Ngokuqhathanisa nezinye izinhlanga, abantu base-Afrika baseMelika ngokomlando baphendula abampofu ekwelashweni.
• Uhlobo lwe-IL28B: Ukuba nale genotype kunganciphisa nezinga lokuphendula kwakho ekwelashweni.
• Ubudala: Ukukhula kweminyaka kwehlisa ushintsho lokufeza i-SVR, kepha hhayi kangako.
• I-Fibrosis: Ukuqubuka okuthuthukile kwezicubu kuhlotshaniswa nezinga lokuphendula eliphansi elingu-10 kuye ku-20.

Phambilini, amazinga e-genotype namazinga e-RNA egciwane lesifo sokusha kwesibindi kohlobo C nawo asizile ukubikezela impendulo yakho ekwelashweni. Kepha ngemithi yesimanje esikhathini se-DAA, badlala indima encane. Ukwelashwa kwe-DAA kunciphise namathuba okwehluleka kokwelashwa. Kodwa-ke, uhlobo oluthile lwegciwane le-hepatitis C, i-genotype 3, liseseyinselele ukwelashwa.

Ukuphindaphinda kwe-Hepatitis C

Kungenzeka ukuthi igciwane libuyele ekutheleleni kabusha noma ekuphindeni. Ukubuyekezwa kwakamuva kwezingcuphe zokuphindeka kabusha kwesifo sokusha kwesibindi kohlobo C.

Izinga lokutheleleka kabusha lingafika kumaphesenti ayi-8 nangaphezulu, ngokuya ngengozi.

Amanani okubuyela emuva ancike ezintweni ezinjenge genotype, uhlobo lwemithi, futhi uma uneminye imibandela ekhona. Isibonelo, isilinganiso sokubuyela emuva kweHarvoni kubikwa ukuthi siphakathi kwephesenti elilodwa kuya kwayisithupha. IHarvoni isetshenziswa kakhulu kubantu abane-genotype 1, kepha kudingeka izifundo eziningi kulokhu.

Ithuba lokuphinde litheleleke lincike engcupheni yakho. Ukuhlaziywa kutholakale izici ezinobungozi zokuphinda kuthathwe kabusha njenge:

• ukusebenzisa noma ukusebenzisa izidakamizwa ezijojwayo
• ukuboshwa
• amadoda alala namadoda
• ama-coinfections, ikakhulukazi lawo abeka engcupheni amasosha akho omzimba

Usengozini ephansi yokuphinda utheleleke uma ungenazo izici eziyingozi. Ingcuphe ephezulu isho ukuthi okungenani unendawo eyodwa ebekiwe engcupheni yokutheleleka futhi. Ingozi yakho iphakeme futhi uma une-HIV, kungakhathalekile ukuthi yiziphi izinto eziyingozi.

Ingozi yokuphindeka kwesifo sokusha kwesibindi kohlobo C kungakapheli iminyaka emihlanu yile:

Ungaphinde utheleleke, noma uzwe ukutheleleka okusha okuvela komunye umuntu onesifo sokusha kwesibindi kohlobo C. Kodwa-ke, kungenzeka ukuthi manje uphila ngaphandle kwesifo sokusha kwesibindi kohlobo C empilweni yakho. Ungazicabangela ukuthethelelwa noma i-hepatitis C engalungile.

Qeda njalo imithi yakho

Ngaso sonke isikhathi landela ukwelashwa okuyalelwa udokotela wakho. Lokhu kwandisa amathuba akho okuxolelwa. Khuluma nodokotela wakho uma uhlangabezana nokungakhululeki noma imiphumela emibi evela emithini yakho. Cela ukwesekwa uma uhlangabezana nemizwa yokudangala. Udokotela wakho angaba nezinsizakusebenza ezikhuthaza isiguli ukuthi zikusebenzise ekwelashweni kwakho nasemgomweni wakho wokukhululeka ku-hepatitis C.