Ukuhlolwa kweMethylmalonic Acid (MMA)
-Delile
- Kuyini ukuhlolwa kwe-methylmalonic acid (MMA)?
- Kusetshenziselwa ini?
- Kungani ngidinga ukuhlolwa kwe-MMA?
- Kwenzekani ngesikhathi sokuhlolwa kwe-MMA?
- Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
- Ingabe zikhona izingozi esivivinyweni?
- Isho ukuthini imiphumela?
- Izinkomba
Kuyini ukuhlolwa kwe-methylmalonic acid (MMA)?
Lokhu kuhlolwa kukala inani le-methylmalonic acid (MMA) egazini noma emchameni wakho. I-MMA yinto eyenziwe ngamanani amancane ngesikhathi sokugaya umzimba. I-Metabolism inqubo yokuthi umzimba wakho ukuguqula kanjani ukudla kube amandla. Uvithamini B12 udlala indima ebalulekile ekusetshenzisweni komzimba. Uma umzimba wakho ungenayo i-vitamin B12 eyanele, izokwenza inani elengeziwe le-MMA. Amazinga aphezulu e-MMA angaba uphawu lokushoda kwe-vitamin B12. Ukushoda kukavithamini B12 kungaholela ezinkingeni ezinkulu zempilo kubandakanya i-anemia, isimo lapho igazi lakho linenani eliphansi kunalelo elijwayelekile lamaseli abomvu egazi.
Amanye amagama: MMA
Kusetshenziselwa ini?
Ukuhlolwa kwe-MMA kuvame ukusetshenziselwa ukuxilonga ukushoda kwamavithamini B12.
Lokhu kuhlolwa kusetshenziselwa ukuxilonga i-methylmalonic acidemia, okuyisifo esingajwayelekile sezakhi zofuzo. Imvamisa kufakwa njengengxenye yochungechunge lwezivivinyo ezibizwa ngokuthi ukuhlolwa kwezingane ezisanda kuzalwa. Ukuhlolwa okusanda kuzalwa kusiza ukuxilonga izimo ezahlukahlukene zezempilo.
Kungani ngidinga ukuhlolwa kwe-MMA?
Ungadinga lokhu kuhlolwa uma unezimpawu zokushoda kukavithamini B12. Lokhu kufaka phakathi:
- Ukukhathala
- Ukuphelelwa isifiso sokudla
- Ukufakwa ezandleni kanye / noma ezinyaweni
- Ukushintsha kwemizwelo
- Ukudideka
- Ukuthukuthela
- Isikhumba esiphaphathekile
Uma unengane entsha, uzohlolwa njengengxenye yokuhlolwa kwezingane ezisanda kuzalwa.
Kwenzekani ngesikhathi sokuhlolwa kwe-MMA?
Amazinga we-MMA angahlolwa egazini noma emchameni.
Ngesikhathi sokuhlolwa kwegazi, uchwepheshe wezokunakekelwa kwempilo uzothatha isampuli yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.
Ngesikhathi sokuhlolwa okusanda kuzalwa, umhlinzeki wezempilo uzohlanza isithende sengane yakho ngotshwala bese ephoqa isithende ngenaliti encane. Umhlinzeki uzoqoqa amaconsi ambalwa egazi bese efaka ibhandishi kusayithi.
Ukuhlolwa komchamo we-MMA kunga-odwa njengokuhlolwa kwesampula yamahora angama-24 noma ukuhlolwa komchamo okungahleliwe.
Ukuhlolwa kwesampula yamahora angama-24, uzodinga ukuqoqa wonke umchamo odluliswe esikhathini esingamahora angama-24. Umhlinzeki wakho wezokunakekelwa kwempilo noma uchwepheshe waselabhorethri uzokunikeza isitsha sokulanda umchamo wakho kanye nemiyalelo yokuthi uwaqoqa kanjani futhi uwagcine amasampula akho. Ukuhlolwa kwesampula yamahora angu-24 ngokuvamile kufaka lezi zinyathelo ezilandelayo:
- Khipha isinye sakho ekuseni bese ususa lowo mchamo kude. Qopha isikhathi.
- Emahoreni angama-24 alandelayo, gcina wonke umchamo wakho odluliswe esitsheni osinikeziwe.
- Gcina isitsha sakho somchamo esiqandisini noma endaweni epholile eneqhwa.
- Buyisela isitsha sesampula ehhovisi lomhlinzeki wakho wezokunakekelwa kwempilo noma elabhorethri njengoba kuyalelwe.
Ukuhlolwa komchamo okungahleliwe, isampula yakho yomchamo ingaqoqwa nganoma yisiphi isikhathi sosuku.
Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
Ungadinga ukuzila ukudla (ungadli noma uphuze) amahora ambalwa ngaphambi kokuhlolwa kwakho. Umhlinzeki wakho wezokunakekelwa kwempilo uzokwazisa uma ngabe kukhona imiyalelo ekhethekile ongayilandela.
Ingabe zikhona izingozi esivivinyweni?
Kunengozi encane kakhulu kuwe noma enganeni yakho ngesikhathi sokuhlolwa kwegazi le-MMA. Ungase ube nobuhlungu obuncane noma ukulinyazwa lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.
Ingane yakho ingazizwa incanyana lapho isithende sibhakwa, futhi umhuzuko omncane ungakheka esizeni. Lokhu kufanele kudlule ngokushesha.
Ayikho ingozi eyaziwayo yokuhlolwa umchamo.
Isho ukuthini imiphumela?
Uma imiphumela yakho ikhombisa ukuphakama kunamazinga ajwayelekile we-MMA, kungasho ukuthi unokuntuleka kwe-vitamin B12. Ukuhlolwa akukwazi ukukhombisa ukuthi unokuntula okungakanani noma ukuthi isimo sakho kungenzeka sibe ngcono noma sibe sibi kakhulu. Ukusiza ukwenza ukuxilongwa, imiphumela yakho ingaqhathaniswa nezinye izivivinyo ezibandakanya ukuhlolwa kwegazi le-homocysteine kanye / noma uvithamini B.
Amazinga aphansi kunamazinga ajwayelekile we-MMA awavamile futhi awathathwa njengenkinga yezempilo.
Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.
Uma ingane yakho inamazinga aphakathi noma aphezulu we-MMA, kungasho ukuthi ine-methylmalonic acidemia. Izimpawu zalesi sifo zingahluka kusuka kokuncane kuya kokubi futhi zingafaka ukuhlanza, ukuphelelwa amandla kwamanzi, ukubambezeleka kwentuthuko, nokukhubazeka kwengqondo. Ukushiywa kungalashwa, kungadala izinkinga ezisongela impilo. Uma ingane yakho kutholakala ukuthi inale nkinga, khuluma nomhlinzeki wezokunakekelwa kwempilo yengane yakho mayelana nezinketho zokwelashwa.
Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.
Izinkomba
- Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Isampula le-24-Hour Urine; [kubuyekezwe 2017 Jul 10; kukhonjiwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/glossary/urine-24
- Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Umzimba; [kubuyekezwe 2017 Jul 10; kukhonjiwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/glossary/metabolism
- Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. I-Methylmalonic Acid; [kubuyekezwe ngo-2019 Dec 6; kucashunwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/methylmalonic-acid
- Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Isampula Yomchamo Engahleliwe; [kubuyekezwe 2017 Jul 10; kukhonjiwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/glossary/random-urine
- UMashi weDimes [i-Intanethi]. Amathafa Amhlophe (NY): Mashi wamaDimes; c2020. Izivivinyo Zokuhlolwa Kwezingane Ezisanda Kuzalwa Zengane Yakho; [kucashunwe ngo-2020 Feb 24]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.marchofdimes.org/baby/newborn-screening-tests-for-your-baby.aspx
- Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co Inc .; c2020. Sibutsetelo se-Amino Acid Metabolic Disorders; [kubuyekezwe ngo-2018 Feb; kukhonjiwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.merckmanuals.com/home/children-s-health-issues/hereditary-metabolic-disorders/overview-of-amino-acid-metabolism-disorders?query=Methylmalonic%20acid
- I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [kucashunwe ngo-2020 Feb 24]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
- Izikhungo Zezempilo Zikazwelonke: Ihhovisi Lezithako Zokudla [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. I-Vitamin B12: Ishidi Leqiniso Labathengi; [kubuyekezwe i-2019 Jul 11; kukhonjiwe ngo-2020 Feb 24]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://ods.od.nih.gov/factsheets/VitaminB12-Consumer
- Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida; c2020. Ukuhlolwa kwegazi kweMethylmalonic acid: Ukubuka konke; [kubuyekezwe ngo-2020 Feb 24; kukhonjiwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/methylmalonic-acid-blood-test
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- I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: I-Methylmalonic Acid (Igazi); [kucashunwe ngo-2020 Feb 24]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=methylmalonic_acid_blood
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Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.