Okungakhethwa komdlavuza we-melanoma nomaphaphu

-Delile

• Intengo
• Ubani ongasebenzisa
• Isetshenziswa kanjani
• Imiphumela engafuneki
• Ngubani ongakwazi ukuthatha

I-Opdivo ikhambi lokuvikela ukugula elisetshenziselwa ukwelapha izinhlobo ezimbili ezihlukene zesifo somdlavuza, i-melanoma, okuwumdlavuza wesikhumba onolaka, nomdlavuza wamaphaphu.

Lo muthi usiza ukuqinisa amasosha omzimba, uthuthukise ukuphendula komzimba kumangqamuzana omdlavuza, uveze imiphumela emibi embalwa kunezindlela zokwelashwa zendabuko ezifana ne-chemotherapy noma i-radiation therapy.

Isithako esisebenzayo e-Opdivo yiNivolumab futhi senziwa ngamalabhorethri eBristol-Myers Squibb. Ngokuvamile, lo muthi awuvamile ukuthengwa, ngoba uyathengwa futhi usetshenziswe ezibhedlela uqobo, noma kunjalo ungathengwa emakhemisi anenkomba yezokwelapha eqinile.

Intengo

EBrazil, inani le-Opdivo libiza, ngokwesilinganiso, ama-reais ayizinkulungwane ezingama-4 we-40mg / 4ml vial, noma i-reais eyizinkulungwane eziyi-10 ye-100mg / 10ml vial, engahluka ngokuya ngekhemisi eliyithengisayo.

Ubani ongasebenzisa

INivolumab ikhonjisiwe ekwelashweni komdlavuza wamaphaphu osuthuthukile osusabalale futhi ongazange welashwe ngempumelelo nge-chemotherapy. Ngaphezu kwalokho, ingasetshenziselwa ukwelapha i-melanoma ezimweni lapho umdlavuza usabalale kabanzi futhi ingasakwazi ukukhishwa ngokuhlinzwa.

Isetshenziswa kanjani

Indlela yokusebenzisa lo muthi kumele ichazwe udokotela ngokuya ngodaba ngalunye, uhlobo lomdlavuza, ngaphezu kwesisindo somzimba womuntu ngamunye, kepha i-Opdivo ivamise ukwelashwa esibhedlela ngqo emthanjeni, ihlanjululwe ngosawoti noma i-glucose , ngezikhathi ezithile imizuzu engama-60 ngosuku.

Ngokuvamile, umthamo onconyiwe ngu-3 mg we-Nivolumab ngekhilogremu yesisindo sakho, njalo emavikini ama-2, angahluka ngokuya ngesibonakaliso sezokwelapha.

Imiphumela engafuneki

Imiphumela emibi ye-Opdivo ifaka phakathi ukukhwehlela okungapheli, ubuhlungu besifuba, ukuphefumula kanzima, isifo sohudo, indle enegazi, ubuhlungu besisu, isikhumba esiphuzi noma amehlo, isicanucanu, ukuhlanza, ukukhathala ngokweqile, ukulunywa nokubomvu kwesikhumba, umkhuhlane, ikhanda elibuhlungu. ubuhlungu nokungaboni kahle.

Noma yiziphi izimpawu ezintsha eziphawuliwe kufanele zibikwe kudokotela futhi ziqashwe, ngoba ukusabela okungathandeki ngeNivolumab kungenzeka nganoma isiphi isikhathi ngesikhathi noma ngemuva kokwelashwa, futhi iziguli kufanele zibhekwe ngokuqhubekayo ngesikhathi sokusetshenziswa ukugwema ukuvela kwezinkinga ezingaba khona. i-pneumonitis, i-colitis, i-hepatitis noma i-nephritis, isibonelo.

Ngubani ongakwazi ukuthatha

Lo muthi uyaphikiswa ezimeni zokungezwani komzimba nomuthi noma kunoma yiziphi izinto ezisetshenziswayo ekwakhiweni.

Azikho ezinye iziphikiso zalo muthi ezichazwe yi-ANVISA, kepha-ke, kufanele isetshenziswe ngokuqapha kwabesifazane abakhulelwe kanye neziguli ezine-pneumonitis, i-colitis, i-hepatitis, izifo ze-endocrine, i-nephritis, izinkinga zezinso noma i-encephalitis.