I-Prednisone ye-Asthma: Ingabe Iyasebenza?

-Delile

• Iphumelela kangakanani i-prednisone ye-asthma?
• Iyini imiphumela emibi?
• Ngizothatha malini?
• Imibuzo okufanele uyibuze udokotela wakho
• Ezinye izinketho
• I-corticosteroids emuncwe
• Ama-mast cell stabilizers
• Izinguquko zeLeukotriene
• Okubalulekile

Ukubuka konke

I-Prednisone iyi-corticosteroid eza ifomu lomlomo noma uketshezi. Isebenza ngokwenza amasosha omzimba ukusiza ukunciphisa ukuvuvukala ezindleleni zomoya zabantu abane-asthma.

I-Prednisone ijwayele ukunikezwa isikhathi esifushane, njengokuthi uma kufanele uye egumbini labezimo eziphuthumayo noma ulaliswe esibhedlela ngenxa yokuhlaselwa yisifuba somoya. Funda amasu okuvimbela ukuhlaselwa yisifuba somoya.

I-Prednisone nayo inganikezwa ukwelashwa kwesikhathi eside uma i-asthma yakho inzima noma kunzima ukuyilawula.

Iphumelela kangakanani i-prednisone ye-asthma?

I-athikili yokubukeza kwiAmerican Journal of Medicine ihlolisise izilingo eziyisithupha ezahlukahlukene zabantu abadala abaneziqephu ze-asthma ezinzima. Kulezi zivivinyo, abantu bathole ukwelashwa kwe-corticosteroid kungakapheli imizuzu engu-90 befika egumbini lezimo eziphuthumayo. Abaphenyi bathole ukuthi la maqembu anezinga eliphansi lokwamukelwa esibhedlela kunabantu abathola i-placebo esikhundleni salokho.

Ngokwengeziwe, ukubuyekezwa ekuphathweni kokuhlaselwa yisifo somoya esihlasela i-asthma ku-American Family Physician kutholakale ukuthi abantu abathumele ekhaya ngemithi enezinsuku ezi-5 kuya kwezingu-10 zemithi engama-50 kuye kwayi-100 milligrams (mg) ye-oral prednisone yehle ngobungozi bokubuyela emuva kwezimpawu zesifuba somoya. Ukubuyekezwa okufanayo kuthi ezinganeni ezineminyaka emi-2 kuya kwengu-15 ubudala, izinsuku ezintathu zokwelashwa kwe-prednisone ku-1 mg ngekhilogremu lesisindo somzimba zingasebenza njengezinsuku ezinhlanu zokwelashwa kwe-prednisone.

Iyini imiphumela emibi?

Imiphumela emibi ye-prednisone ingafaka:

• ukugcinwa koketshezi
• ukwanda kwesifiso sokudla
• ukuzuza kwesisindo
• isisu esibuhlungu
• izinguquko zemizwa noma zokuziphatha
• umfutho wegazi ophakeme
• ukwanda kokuthambekela kokutheleleka
• ukukhumuzeka kwamathambo
• izinguquko zamehlo, njenge-glaucoma noma i-cataract
• umthelela omubi ekukhuleni noma entuthukweni (lapho kunqunyelwe izingane)

Kubalulekile ukuqaphela ukuthi eminingi yale miphumela engemihle, efana ne-osteoporosis kanye nokushintsha kwamehlo, kwenzeka kakhulu ngemuva kokusebenzisa isikhathi eside. Azivamile ngomuthi wesikhashana we-prednisone. Bheka lezi zithombe ezihlekisayo ezinemiphumela emibi engaziwa ye-prednisone.

Ngizothatha malini?

I-Prednisone iyatholakala njengethebhulethi yomlomo noma isisombululo soketshezi ngomlomo e-United States. Ngenkathi ifana, i-prednisone ayifani ne-methylprednisolone, etholakala njengesisombululo somjovo kanye ne-tablet yomlomo. Ngokuvamile, i-oral prednisone isetshenziswa njengokwelashwa komugqa wokuqala kwesifuba somoya esibucayi ngoba kokubili kulula ukuthatha futhi akubizi kakhulu.

Isilinganiso sobude besidakamizwa se-corticosteroids esifana ne-prednisone yizinsuku ezinhlanu kuya kweziyi-10. Kubantu abadala, isilinganiso esijwayelekile akuvamile ukuthi seqe ama-80 mg. Umthamo omkhulu ovame kakhulu yi-60 mg. Imithamo emikhulu kune-50 kuya ku-100 mg ngosuku ayiboniswa ukuthi inenzuzo enkulu yokukhululeka.

Uma uphuthelwa umthamo we-prednisone, kufanele uthathe umthamo ongabanjwanga ngokushesha nje lapho ukhumbula. Uma sekuyisikhathi sedosi yakho elandelayo, weqa umthamo ongabanjwanga bese uthatha umthamo olandelayo ohleliwe njalo.

Akufanele uthathe umthamo owengeziwe ukwenza umthamo owuphuthelwe. Ukuze uvimbele isisu esithukuthele, kungcono ukuthatha i-prednisone ngokudla noma ubisi.

Imibuzo okufanele uyibuze udokotela wakho

IPrednisone ayiphephile ukuyithatha ngenkathi ukhulelwe. Kufanele ngokushesha wazise udokotela wakho uma ukhulelwa ngenkathi uthatha i-prednisone.

Ngoba i-prednisone isebenza kumasosha omzimba, ungahle uthambekele ekuthelelekeni. Kufanele ukhulume nodokotela wakho uma unesifo esiqhubekayo noma usanda kuthola umuthi wokugoma.

Kunemithi eminingi engasebenzisana kabi ne-prednisone. Kubalulekile ukuthi udokotela wakho aziswe ngayo yonke imithi oyiphuzayo. Kufanele ukhulume nodokotela wakho uma njengamanje usebenzisa noma yiziphi izinhlobo zemithi ezilandelayo:

• abahlinza igazi
• imithi yesifo sikashukela
• imishanguzo yesifo sofuba
• ama-antibiotic ohlobo lwe-macrolide, njenge-erythromycin (E.E.S.) noma i-azithromycin (iZithromax)
• i-cyclosporine (iSandimmune)
• i-estrogen, kubandakanya nemithi yokulawula ukubeletha
• izidakamizwa ezingezona ukuvuvukala (ama-NSAID), njenge-aspirin
• isisu
• ama-anticholinesterases, ikakhulukazi kubantu abane-myasthenia gravis

Ezinye izinketho

Kuneminye imishanguzo elwa nokuvuvukala engasetshenziswa njengengxenye yokwelashwa kwesifuba somoya. Lokhu kufaka phakathi:

I-corticosteroids emuncwe

Ama-corticosteroids angenisiwe ayasebenza kakhulu ekunciphiseni inani lokuvuvukala kanye namafinyila asendleleni yomoya. Ngokuvamile zithathwa nsuku zonke. Ziza ngezindlela ezintathu: i-metered dose inhaler, i-powder eyomile inhaler, noma isisombululo se-nebulizer.

Le mithi isiza ukuvimbela izimpawu ze-asthma, hhayi ukwelapha izimpawu.

Uma ithathwa ngemithamo ephansi, ama-corticosteroids ahogelwayo anemiphumela emibi embalwa. Uma uthatha umthamo ophakeme, ezimweni ezingavamile ungathola igciwane lesikhunta lomlomo elibizwa nge-thrush.

Ama-mast cell stabilizers

Le mithi isebenza ngokuvimbela ukukhishwa kwenhlanganisela ebizwa nge-histamine ngamaseli omzimba athile emzimbeni wakho (amaseli amangqamuzana). Zisetshenziselwa ukuvimbela izimpawu ze-asthma, ikakhulukazi ezinganeni nakubantu abane-asthma ebangelwa ukuzivocavoca umzimba.

Ama-mast cell stabilizers ngokuvamile athathwa izikhathi ezimbili noma ezine ngosuku futhi anemiphumela engemihle embalwa. Umphumela wecala ovame kakhulu umphimbo owomile.

Izinguquko zeLeukotriene

Izinguquko zeLeukotriene uhlobo olusha lwemithi yesifuba somoya. Zisebenza ngokuvimba ukusebenza kwamakhemikhali athile, abizwa ngama-leukotrienes. AmaLeukotrienes ayenzeka ngokwemvelo emzimbeni wakho futhi angadala ukuncipha kwemisipha yomoya.

La maphilisi angaphuzwa kanye noma kane ngosuku. Imiphumela emibi kakhulu yikhanda nesicanucanu.

Okubalulekile

I-Prednisone iyi-corticosteroid ejwayele ukunikezwa amacala abucayi e-asthma. Kuyasiza ukunciphisa ukuvuvukala ezindleleni zomoya kubantu ababhekene nokuhlaselwa yisifuba somoya.

IPrednisone kutholakale ukuthi iyasebenza ekunciphiseni ukuphindeka kwezimpawu zesifuba somoya kulandela ukuvakashela igumbi labezimo eziphuthumayo noma isibhedlela.

Imiphumela emibi eminingi ehambisana ne-prednisone yenzeka ngesikhathi sokusetshenziswa kwesikhathi eside.

IPrednisone ingaxhumana nezinye izinhlobo zemithi. Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke eminye imishanguzo oyiphuzayo ngaphambi kokuqala ku-prednisone.