Ukungalingani Kwe-Ovarian Okuyinhloko

-Delile

• Isifinyezo
• Kuyini ukungasebenzi kahle kwe-ovarian okuyinhloko (POI)?
• Yini ebanga ukungasebenzi kahle kwe-ovarian okuyinhloko (POI)?
• Ngubani osemngciphekweni wokungeneli kwe-ovarian okuyinhloko (POI)?
• Ziyini izimpawu zokunganeleki okuyisisekelo kwe-ovarian (POI)?
• Yiziphi ezinye izinkinga ezingabangelwa ukunganeleki kwe-ovarian okuyinhloko (POI)?
• Kutholakalaphi ukutholakala kwama-ovarian primary (POI) okuyinhloko?
• Ngabe i-primary ovarian insufficiency (POI) iphathwa kanjani?

Isifinyezo

Kuyini ukungasebenzi kahle kwe-ovarian okuyinhloko (POI)?

Ukwehluleka kwe-ovarian okuyisisekelo (POI), okwaziwa nangokuthi ukwehluleka kwe-ovarian ngaphambi kwesikhathi, kwenzeka lapho amaqanda wesifazane eyeka ukusebenza ngokujwayelekile ngaphambi kokuba abe neminyaka engama-40.

Abesifazane abaningi ngokwemvelo bathola inzalo encishisiwe lapho beneminyaka engaba ngu-40 ubudala. Bangase baqale ukuthola izikhathi ezingajwayelekile zokuya esikhathini njengoba bedlulela esikhathini sokuya esikhathini. Kwabesifazane abane-POI, izikhathi ezingajwayelekile nokuncipha kokuzala kuqala ngaphambi kweminyaka yobudala engama-40. Kwesinye isikhathi kungaqala eminyakeni yobusha.

I-POI yehlukile ekunqamukeni kokuya esikhathini ngaphambi kwesikhathi. Ngokunqamuka kokuya esikhathini ngaphambi kwesikhathi, izikhathi zakho ziyama ngaphambi kweminyaka yobudala engama-40. Awusakwazi ukukhulelwa. Isizathu singaba semvelo noma kungaba yisifo, ukuhlinzwa, ukwelashwa ngamakhemikhali noma imisebe. Nge-POI, abanye besifazane basenezikhathi ezithile. Bangaze bakhulelwe. Ezimweni eziningi ze-POI, imbangela ayaziwa.

Yini ebanga ukungasebenzi kahle kwe-ovarian okuyinhloko (POI)?

Cishe ku-90% wamacala, imbangela ngqo ye-POI ayaziwa.

Ucwaningo lukhombisa ukuthi i-POI ihlobene nezinkinga ngama-follicles. Ama-follicles amasaka amancane kuma-ovari akho. Amaqanda akho ayakhula futhi avuthwe ngaphakathi kuwo. Uhlobo olulodwa lwenkinga ye-follicle ukuthi uphelelwa ama-follicles asebenzayo ngaphambi kokujwayelekile. Okunye ukuthi ama-follicles awasebenzi kahle. Ezimweni eziningi, imbangela yenkinga ye-follicle ayaziwa. Kepha kwesinye isikhathi imbangela kungenzeka

• Izinkinga zofuzo ezifana ne-Fragile X syndrome ne-Turner syndrome
• Inani eliphansi lama-follicles
• Izifo ezizimele, kufaka phakathi i-thyroiditis nesifo se-Addison
• I-Chemotherapy noma i-radiation therapy
• Izinkinga ze-Metabolic
• Ubuthi, njengentuthu kagwayi, amakhemikhali, kanye nezibulala-zinambuzane

Ngubani osemngciphekweni wokungeneli kwe-ovarian okuyinhloko (POI)?

Izici ezithile zingakhuphula ubungozi besifazane be-POI:

• Umlando womndeni. Abesifazane abanomama noma udadewabo abane-POI maningi amathuba okuthi babe nayo.
• Izakhi zofuzo. Olunye ushintsho kuzakhi zofuzo nezimo zofuzo lubeka abesifazane engcupheni ephezulu ye-POI. Isibonelo, abesifazane i-Fragile X syndrome noma i-Turner syndrome basengozini enkulu.
• Izifo ezithile, njengezifo ezizimele kanye nokutheleleka ngegciwane
• Ukwelashwa komdlavuza, okufana nokwelashwa ngamakhemikhali nokwelashwa ngemisebe
• Ubudala. Abesifazane abasebancane bangathola i-POI, kepha iba yinto ejwayelekile phakathi kweminyaka yobudala engama-35-40.

Ziyini izimpawu zokunganeleki okuyisisekelo kwe-ovarian (POI)?

Isibonakaliso sokuqala se-POI imvamisa siyizikhathi ezingajwayelekile noma ezingabanjwanga. Izimpawu zakamuva zingafana nalezo zokunqamuka kokuya esikhathini ngokwemvelo:

• Ukushisa okushisayo
• Ukujuluka ebusuku
• Ukuthukuthela
• Ukuhlushwa okungalungile
• Ukwehla kobulili
• Ubuhlungu ngesikhathi socansi
• Ukoma kwesitho sangasese sowesifazane

Kwabesifazane abaningi abane-POI, ukukhathazeka ukukhulelwa noma ukungabi nenzalo yisizathu sokuthi baye kumhlinzeki wabo wokunakekelwa kwezempilo.

Yiziphi ezinye izinkinga ezingabangelwa ukunganeleki kwe-ovarian okuyinhloko (POI)?

Njengoba i-POI ikubangela ukuthi ube namazinga aphansi ama-hormone athile, usengozini enkulu yezinye izimo zezempilo, kufaka phakathi

• Ukukhathazeka nokudangala. Izinguquko zeHormonal ezibangelwa yi-POI zingaba nomthelela ekukhathazekeni noma ziholele ekucindezelekeni.
• Isifo seso elomile nesifo samehlo. Abanye besifazane abane-POI banenye yalezi zimo zamehlo. Kokubili kungadala ukungaphatheki kahle futhi kungaholela ekuboneni ukufiphala. Uma ingalashwa, lezi zimo zingadala ukulimala kwamehlo unomphela.
• Isifo senhliziyo. Amazinga aphansi e-estrogen angathinta imisipha etholakala emithanjeni futhi angakhuphula i-cholesterol eningi emithanjeni. Lezi zinto zandisa ubungozi be-atherosclerosis (ukuqina kwemithambo).
• Ukungabi nenzalo.
• Umsebenzi we-thyroid ophansi. Le nkinga ibizwa nangokuthi i-hypothyroidism. Indlala yegilo yindlala eyenza ama-hormone alawula umzimba wakho nezinga lamandla. Amazinga aphansi ama-hormone e-thyroid angathinta imetabolism yakho futhi angadala amandla aphansi kakhulu, ukuvilapha kwengqondo nezinye izimpawu.
• I-osteoporosis. Ihomoni i-estrogen isiza ukugcina amathambo eqinile. Ngaphandle kwe-estrogen eyanele, abesifazane abane-POI bavame ukuba ne-osteoporosis. Yisifo samathambo esidala amathambo abuthakathaka, aqhephukile okungenzeka ukuthi aphuke.

Kutholakalaphi ukutholakala kwama-ovarian primary (POI) okuyinhloko?

Ukuhlonza i-POI, umhlinzeki wakho wezokunakekelwa kwempilo angakwenza

• Umlando wezokwelapha, kufaka phakathi ukubuza ukuthi unazo yini izihlobo ezine-POI
• Ukuhlolwa kokukhulelwa, ukwenza isiqiniseko sokuthi awukhulelwe
• Ukuhlolwa ngokomzimba, ukubheka izimpawu zokunye ukuphazamiseka okungadala izimpawu zakho
• Ukuhlolwa kwegazi, ukubheka amazinga athile ama-hormone. Ungase futhi ube nokuhlolwa kwegazi ukwenza ukuhlaziywa kwe-chromosome. I-chromosome yingxenye yeseli equkethe imininingwane yezofuzo.
• I-pelvic ultrasound, ukubona ukuthi ama-ovari akhulisiwe yini noma anezintambo eziningi

Ngabe i-primary ovarian insufficiency (POI) iphathwa kanjani?

Njengamanje, alukho umuthi oqinisekisiwe wokubuyisela umsebenzi ojwayelekile kumaqanda esifazane. Kepha kukhona ukwelashwa kwezinye zezimpawu ze-POI. Kukhona nezindlela zokwehlisa izingozi zakho zempilo futhi welaphe izimo ezingabangelwa yi-POI:

• Ukwelashwa okushintsha iHormone (HRT). I-HRT iyindlela yokwelashwa ejwayelekile kakhulu. Inika umzimba wakho ama-estrogen namanye ama-hormone amaqanda akho angakwenzi. I-HRT ithuthukisa impilo yezocansi futhi yehlisa ubungozi besifo senhliziyo kanye ne-osteoporosis. Imvamisa uyithatha ize ibe cishe neminyaka engama-50; lokho kumayelana nesikhathi lapho ukunqamuka kokuya esikhathini kuvame ukuqala khona.
• Izithako ze-calcium nevithamini D. Ngoba abesifazane abane-POI basengozini enkulu yokuba ne-osteoporosis, kufanele uthathe i-calcium novithamini D nsuku zonke.
• In vitro fertilization (IVF). Uma une-POI futhi ufisa ukukhulelwa, ungacabanga ukuzama i-IVF.
• Ukuvivinya umzimba njalo kanye nesisindo somzimba esinempilo. Ukuvivinya umzimba njalo nokulawula isisindo sakho kunganciphisa amathuba okuba ne-osteoporosis nesifo senhliziyo.
• Ukwelashwa kwezimo ezihambisanayo. Uma unesimo esihlobene ne-POI, kubalulekile ukuphatha lokho futhi. Ukwelashwa kungafaka imithi namahomoni.

I-NIH: Isikhungo Sikazwelonke Sezempilo Yezingane Nokuthuthukiswa Kwabantu