I-Progressive-Relapsing Multiple Sclerosis (PRMS)

-Delile

• Ukuchaza “ukubuyela emuva” ku-PPMS esebenzayo
• Izimpawu ze-PPMS
• Ukuqhubeka kwe-PPMS
• Ukuhlonza i-PPMS
• Ukwelapha i-PPMS
• Umbono we-PPMS

Kuyini okuqhubekayo ukubuyela emuva kwe-multiple sclerosis (PRMS)?

Ngo-2013, ochwepheshe bezokwelapha bazichaza kabusha izinhlobo ze-MS. Ngenxa yalokho, i-PRMS ayisabhekwa njengenye yezinhlobo ezihlukile ze-MS.

Abantu okungenzeka ukuthi bathola ukuxilongwa kwe-PRMS esikhathini esedlule manje sebethathwa njengabane-MS eyisiqalo esithuthukayo nesifo esisebenzayo.

I-multiple sclerosis eqhubekayo eqhubekayo (PPMS) iyaziwa ngezimpawu eziba zimbi ngokuhamba kwesikhathi. Lesi sifo singase sibonakale “njengesisebenza” noma “esingasebenzi.” I-PPMS ithathwa njengesebenzayo uma kunezimpawu ezintsha noma izinguquko kuskena se-MRI.

Izimpawu ezivame kakhulu ze-PPMS ziholela kuzinguquko ekuhambeni, futhi zingafaka:

• izinguquko ku-gait
• izingalo nemilenze elukhuni
• imilenze esindayo
• ukungakwazi ukuhamba amabanga amade

I-multiple sclerosis (PRMS) eqhubekayo ibhekisela ku-PPMS enesifo esisebenzayo. Amaphesenti amancane abantu abane-multiple sclerosis (MS) anayo le nguqulo ephindaphindekayo yesifo.

Ukuchaza “ukubuyela emuva” ku-PPMS esebenzayo

Ekuqaleni kwe-MS, abanye abantu babhekana nokushintshashintsha kwezimpawu. Kwesinye isikhathi azikhombisi zimpawu ze-MS izinsuku noma amasonto ngesikhathi.

Kodwa-ke, ngezikhathi zokulala, izimpawu zingavela ngaphandle kwesixwayiso. Lokhu kungabizwa ngokuthi yi-MS ebuyela emuva, ukukhuphuka, noma ukuhlaselwa. Ukubuyela emuva uphawu olusha, ukuphindeka kwesifo esidala ebesingcono ngaphambili, noma ukuwohloka kwesimpawu esidala esihlala isikhathi esingaphezu kwamahora angama-24.

Ukubuyela emuva ku-PPMS esebenzayo kwehlukile ekubuyiseleni emuva ekubuyiseleni emuva-ekunciphiseni i-multiple sclerosis (RRMS).

Abantu abane-PPMS bathola udwendwe lwezimpawu kancane kancane. Izimpawu zingase zibe ngcono kancane kepha zingapheli ngokuphelele. Ngenxa yokuthi izimpawu zokuphindaphinda azipheli ku-PPMS, umuntu one-PPMS uzoba nezimpawu eziningi ze-MS kunomuntu one-RRMS.

Uma i-PPMS esebenzayo ikhula, ukubuyela emuva kungenzeka ngokuzenzakalela, noma ngaphandle kokwelashwa.

Izimpawu ze-PPMS

Izimpawu zokuhamba ziphakathi kwezimpawu ezivame kakhulu ze-PPMS, kepha ubunzima nezinhlobo zezimpawu zingahluka kuye ngomuntu. Ezinye izimpawu ezivamile ze-PPMS esebenzayo zingafaka:

• ukuphazamiseka kwemisipha
• imisipha ebuthakathaka
• kunciphise ukusebenza kwesinye, noma ukungasebenzi
• isiyezi
• ubuhlungu obungapheli
• umbono uyashintsha

Njengoba lesi sifo siqhubeka, i-PPMS ingadala izimpawu ezingejwayelekile ezifana ne:

• izinguquko enkulumweni
• ukuthuthumela
• ukulahlekelwa ukuzwa

Ukuqhubeka kwe-PPMS

Ngaphandle kokubuyela emuva, i-PPMS esebenzayo nayo imakwe ngokuqhubeka okungaguquki kokuncipha komsebenzi wezinzwa.

Odokotela abakwazi ukubikezela isilinganiso esiqondile sokuqhubeka kwe-PPMS. Ezimweni eziningi, ukuqhubeka kuyinqubo ehamba kancane kepha engaguquki eqhubeka iminyaka eminingana. Amacala amabi kakhulu e-PPMS abonakala ngokuqhubeka ngokushesha.

Ukuhlonza i-PPMS

I-PPMS ingaba nzima ukuyithola ekuqaleni. Lokhu ngokwengxenye ngenxa yokuthi ukubuyela emuva ku-PPMS akubonakali kangako njengoba kunjalo nakwezinye izinhlobo ze-MS ezingezinzima kangako.

Abanye abantu badlulisa ukubuyela emuva njengomphumela wokuba nezinsuku ezimbi kunokucabanga ukuthi bayizimpawu zokwanda kwezifo. I-PPMS itholakala ngosizo lwe:

• ukuhlolwa kwelebhu, njengokuhlolwa kwegazi kanye nokubhoboza i-lumbar
• Ukuskena kwe-MRI
• izivivinyo zezinzwa
• umlando wezokwelapha womuntu ochaza izinguquko zezimpawu

Ukwelapha i-PPMS

Ukwelashwa kwakho kuzogxila ekusizeni ukuphatha ukubuyela emuva. Imithi kuphela evunyelwe yi-FDA ye-PPMS yi-ocrelizumab (Ocrevus).

Imithi iyisici esisodwa sokwelashwa kwe-MS. Udokotela wakho futhi angancoma izinguquko zendlela yokuphila ukusiza ukunciphisa izimpawu zakho nokuthuthukisa ikhwalithi yempilo. Ukuvivinya umzimba njalo nokudla okunomsoco kungasiza ekunakekelweni kwezokwelapha kwe-MS.

Umbono we-PPMS

Okwamanje alikho ikhambi le-MS.

Njengezinye izinhlobo zesifo, ukwelashwa kungasiza ekunciphiseni ukuqhubeka kwe-PPMS. Ukwelashwa kunganciphisa nezimpawu.

Ukungenelela kokuqala kwezokwelapha kungasiza ekuvikeleni lesi sifo ekuthikamezeni kakhulu izinga lakho lempilo. Kodwa-ke, kubalulekile ukuthola ukuxilongwa okufanelekile kudokotela wakho ukuze uqiniseke ukuthi uthola ukunakekelwa okwanele.

Abaphenyi bayaqhubeka nokutadisha i-MS ukuqonda ubunjalo besifo futhi mhlawumbe bafune nokwelashwa.

Izifundo zokwelashwa ze-PPMS zande kakhulu kunezinye izinhlobo zesifo ngoba akulula kangako ukusibona. Inqubo yokuqashwa kwezilingo zomtholampilo ingaba nzima uma unikezwa ukutholakala kwalolu hlobo lwe-MS.

Izilingo eziningi zemithi yokufunda ye-PPMS ukuphatha izimpawu. Uma unentshisekelo yokubamba iqhaza esivivinyweni somtholampilo, xoxa ngemininingwane nodokotela wakho.