I-Pigmented Villonodular Synovitis (PVNS)

-Delile

• Yini ebangela i-PVNS?
• Lapho kutholakala emzimbeni
• Izimpawu
• Ukwelashwa
• Ukuhlinzwa kwe-arthroscopic
• Ukuhlinzwa okuvulekile
• Ukubuyiselwa ngokuhlanganyela
• Ukulungiswa kwetendon
• Imisebe
• Imithi
• Isikhathi sokutakula ukuhlinzwa
• Ukuguqulwa kwendlela yokuphila
• Ukudla okudlela endlini

Ukubuka konke

I-synovium ungqimba lwezicubu ezigcwala amalunga. Iphinde ikhiqize uketshezi ukuthambisa amalunga.

Ku-pigment villonodular synovitis (PVNS), i-synovium iyaqina, yakhe ukukhula okubizwa ngokuthi yi-tumor.

I-PVNS ayiwona umdlavuza. Ayikwazi ukusakazeka kwezinye izingxenye zomzimba, kodwa ingakhula ize ifike eqophelweni lapho ilimaza khona amathambo aseduze futhi ekugcineni ibangele isifo samathambo. Ukukhula okweqile kwendwangu ehlangene nakho kubangela ubuhlungu, ukuqina, nezinye izimpawu.

I-PVNS iyingxenye yeqembu lezicubu ezingenasifo somdlavuza ezithinta amalunga, okuthiwa i-tenosynovial giant cell tumors (TGCTs). Kunezinhlobo ezimbili ze-PVNS:

• I-PVNS yendawo noma ye-nodular ithinta indawo eyodwa kuphela yokujoyina noma imisipha kuphela esekela ukujoyina.
• Ukusabalalisa i-PVNS kuhilela ulwelwesi oluhlangene lonke. Kungaba nzima ukwelashwa kune-PVNS yendawo.

I-PVNS yisimo esingajwayelekile. Ithinta kuphela mayelana.

Yini ebangela i-PVNS?

Odokotela abazi ukuthi yini ngempela ebangela lesi simo. Kungahle kube nokuxhumana phakathi kwe-PVNS nokulimala muva nje. Izakhi zofuzo ezithinta ukukhula kwamaseli ejoyini nazo zingadlala indima.

I-PVNS ingaba yisifo sokuvuvukala, esifana nesifo samathambo. bathole amazinga aphezulu amakaki wokuvuvukala afana ne-C-reactive protein (CRP) kubantu abanalesi simo. Noma, kungahle kubangelwe ukukhula kwamaseli okungamakiwe, okufana nomdlavuza.

Yize i-PVNS ingaqala nganoma yisiphi isikhathi, ivame ukuthinta abantu abaseminyakeni engama-30 nengama-40. Abesifazane mancane amathuba okuthi bathole lesi simo kunabesilisa.

Lapho kutholakala emzimbeni

Cishe amaphesenti angama-80 wesikhathi, i-PVNS isemadolweni. Isiza sesibili esivame kakhulu isinqe.

I-PVNS nayo ingathinta okulandelayo:

• ihlombe
• indololwane
• isihlakala
• iqakala
• umhlathi (kuyaqabukela)

Akuvamile ukuthi i-PVNS ibe sejoyini elingaphezu kwelilodwa.

Izimpawu

Njengoba i-synovium ikhula, ikhiqiza ukuvuvukala ejoyintini. Ukuvuvukala kungabukeka kumangalisa, kepha imvamisa akunabuhlungu.

Ezinye izimpawu zifaka:

• ukuqina
• ukunyakaza okulinganiselwe kujoyini
• ukuphuma, ukukhiya, noma ukubamba umuzwa lapho uhambisa ilunga
• imfudumalo noma isisa phezu kwesihlanganisi
• ubuthakathaka emalungeni

Lezi zimpawu zingavela isikhathi esithile bese ziyanyamalala. Njengoba lesi sifo siqhubeka, singadala ukuqaqamba kwamalunga ejoyintini.

Ukwelashwa

Isimila sizoqhubeka nokukhula. Ishiye ingalashwa, izolimaza ithambo eliseduze. Ukwelashwa okuyinhloko kwe-TGCT ukuhlinzwa ukususa ukukhula. Ukuhlinzwa kungenziwa ngezindlela ezahlukahlukene ezahlukahlukene.

Ukuhlinzwa kwe-arthroscopic

Le nqubo yokuhlasela kancane isebenzisa ukuqhekeka okumbalwa. Udokotela ohlinzayo ubeka indawo encane, ekhanyisiwe ngekhamera ngesinye seziqephu. Izinsimbi ezincane zingena kokunye ukuvuleka.

Udokotela ohlinzayo angabona ngaphakathi kwejoyini kumqapha wevidiyo. Ngesikhathi senqubo, udokotela ohlinzayo uzosusa isimila nezindawo ezilimele zolwelwesi oluhlangene.

Ukuhlinzwa okuvulekile

Kwesinye isikhathi ukusikeka okuncane ngeke kunikeze udokotela ohlinzayo indawo eyanele yokukhipha lonke isimila. Kulezi zimo, ukuhlinzeka kwenziwa njengenqubo evulekile ngokusebenzisa imbobo eyodwa enkulu. Lokhu kuvumela udokotela ukuthi abone sonke isikhala esihlangene, esivame ukudingeka kwizicubu ngaphambili noma emuva kwedolo.

Kwesinye isikhathi, odokotela abahlinzayo basebenzisa inhlanganisela yamasu avulekile nawokuthwebula ejoyintini elifanayo.

Ukubuyiselwa ngokuhlanganyela

Uma isifo samathambo sonakalise ijoyinti elingalungiseki, udokotela ohlinzayo angalisusa lonke noma ingxenye yalo. Lapho nje izindawo ezilimele sezisusiwe, kufakwa ezinye izinto ezenziwe ngensimbi, upulasitiki, noma i-ceramic. Izimila ngokuvamile ngeke zibuye ngemuva kokufakwa ngokuhlanganyela.

Ukulungiswa kwetendon

I-PVNS ekugcineni ingalimaza ithenda ejoyintini. Uma lokhu kwenzeka, ungaba nenqubo yokuthunga imikhawulo edabukile yethenda ibuyele ndawonye.

Imisebe

Ukuhlinzwa akuphumeleli ngaso sonke isikhathi ekususeni sonke isimila. Abanye abantu abalona ithuba lokuhlinzwa, noma bakhetha ukungabi nalo. Kulezi zimo, imisebe ingaba inketho.

Imisebe isebenzisa amagagasi anamandla amakhulu ukuqeda isimila. Esikhathini esedlule, ukwelashwa ngemisebe kwakuvela emshinini ongaphandle komzimba.

Ngokwandayo, odokotela basebenzisa imisebe ye-intra-articular, ejova uketshezi olusebenzisa imisebe yelungu.

Imithi

Abaphenyi bafunda imithi embalwa ye-PVNS ezivivinyweni zokwelashwa. Iqembu lezidakamizwa ze-biologic lingasiza ekuvikeleni amaseli ekuqoqeni amalunga ahlangene kanye nokwakha. Le mithi ihlanganisa:

• umagazine
• emactuzumab
• imatinib mesylate (Gleevec)
• I-nilotinib (Tasigna)
• pexidartinib

Isikhathi sokutakula ukuhlinzwa

Kuthatha isikhathi esingakanani ukuthola kabusha kuncike enkambisweni oke waba nayo. Kungathatha izinyanga ezimbalwa ukululama ngemuva kokuhlinzwa okuvulekile ngokuphelele. Imvamisa, ukuhlinzwa kwe-arthroscopic kuholela esikhathini esisheshayo sokutakula samasonto ambalwa noma ngaphansi.

Ukwelashwa ngokomzimba kuyisihluthulelo sokululama ngokushesha. Ngalezi zikhathi, uzofunda ukuzivocavoca ukuze uqinise futhi uthuthukise ukuguquguquka kokuhlanganyela.

Ukuguqulwa kwendlela yokuphila

Kubalulekile ukuphumuza amalunga athintekile lapho kubuhlungu, nangemva kokuhlinzwa. Thatha ingcindezi emalungeni athwala isisindo njengamadolo nesinqe ngokuhlala kude nezinyawo zakho nangokusebenzisa izinduku lapho uhamba.

Ukuvivinya umzimba njalo kungakusiza ugcine ukunyakaza ejoyintini futhi uvimbele ukuqina. Umelaphi angakhombisa ukuthi yikuphi ukuzivocavoca okufanele ukwenze, nokuthi ungakwenza kanjani ngokuphepha nangempumelelo.

Ukuze unciphise ukuvuvukala nobuhlungu, bamba iqhwa kulungu elithintekile imizuzu eyi-15 kuye kwengama-20 ngesikhathi, izikhathi eziningana ngosuku. Songa iqhwa ngethawula ukuvimbela ukuthi lingashisi isikhumba sakho.

Ukudla okudlela endlini

Ukuhlinzwa kuvame ukuphumelela kakhulu ekwelapheni i-PVNS, ikakhulukazi uhlobo lwendawo. Phakathi kwamaphesenti ayi-10 namaphesenti angama-30 wezimila ezisakazwayo zikhula emuva ngemuva kokuhlinzwa. Uzobona udokotela okwelashwa iminyaka eminingana ngemuva kokuhlinzwa ukuze aqiniseke ukuthi isimila sakho asikabuyi.