Yini iRed Man Syndrome?

-Delile

• Izimpawu
• Izithombe ze-red man syndrome
• Izimbangela
• Izici zobungozi
• Isigameko
• Ukwelashwa
• Umbono

Ukubuka konke

I-Red man syndrome iyindlela ejwayelekile kakhulu yokusabela kumuthi i-vancomycin (Vancocin). Kwesinye isikhathi kubizwa ngokuthi yi-red neck syndrome. Igama livela ekuqubukeni okubomvu okuvela ebusweni, entanyeni, nasemzimbeni womuntu othintekile.

IVancomycin iyi-antibiotic. Kuvame ukusetshenziselwa ukwelapha ukutheleleka okunamandla kwamagciwane, kufaka phakathi lawo abangelwa yi-staphylococci emelana nemethicillin, evame ukubizwa nge-MRSA. Umuthi uvimbela amabhaktheriya ekwakheni izindonga zamangqamuzana, okwenza ukuthi amagciwane afe. Lokhu kuvimbela ukukhula okwengeziwe futhi kumise ukusabalala kwesifo.

IVancomycin nayo inganikezwa ezimweni lapho umuntu enenkinga yokungezwani komzimba nezinye izinhlobo zama-antibiotic, njenge-penicillin.

Izimpawu

Uphawu olukhulu lwe-red man syndrome ukuqubuka okukhulu okubomvu ebusweni, entanyeni, nasemzimbeni ophezulu. Imvamisa kwenzeka ngesikhathi noma ngemuva kokufakwa kwe-vancomycin emthanjeni (IV). Ezimweni eziningi, uma umuthi unikezwa ngokushesha, kulapho kuvela khona ukuqubuka.

Ukuqhuma kuvame ukuvela kungakapheli imizuzu eyi-10 kuya kwengu-30 yokwelashwa kwe-vancomycin kuqala. Ukuphendula okubambezelekile kuye kwabonakala nakubantu abebelokhu bethola i-vancomycin infusions izinsuku ezimbalwa.

Ezimweni eziningi, ukusabela okulandela ukumfakelwa kwe-vancomycin kumnene kangangokuba kungahle kungabonakali. Ukungakhululeki nemizwa yokushiswa nokulunywa nakho kubonakala kaningi. Ezinye izimpawu ezingavamile kakhulu kodwa ezimbi kakhulu zifaka:

• i-hypotension (umfutho wegazi ophansi)
• ukuphelelwa umoya
• isiyezi
• ikhanda
• Ukugodola
• imfiva
• ubuhlungu besifuba

Izithombe ze-red man syndrome

Izimbangela

Odokotela baqale bakholelwa ukuthi i-red man syndrome ibangelwa ukungcola kumalungiselelo e-vancomycin. Ngalesi sikhathi, lesi sifo sasivame ukubizwa ngegama lesidlaliso elithi “Mississippi Mud.” Kodwa-ke, i-red man syndrome iqhubekile ukwenzeka naphezu kokuthuthuka okukhulu kokuhlanzeka kwamalungiselelo e-vancomycin.

Manje sekuyaziwa ukuthi i-red man syndrome ibangelwa ukwanda ngokweqile kwamaseli omzimba athile emzimbeni ngenxa ye-vancomycin. Lawa maseli, abizwa ngokuthi ama-mast cells, ahlotshaniswa nokungezwani komzimba. Uma kukhuliswa ngokweqile, amangqamuzana omzimba akhiqiza inani elikhulu lengxube ebizwa nge-histamine. I-Histamine iholela ezinkomba ze-red man syndrome.

Ezinye izinhlobo zama-antibiotics, njenge-ciprofloxacin (Cipro), i-cefepime, ne-rifampin (i-Rimactane, i-Rifadin), nayo ingadala i-red man syndrome ezimweni ezingavamile.

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Izici zobungozi

Isici esiyinhloko sengozi yokuthuthukisa i-red man syndrome ukuthola ukumnika i-vancomycin ngokushesha okukhulu. Ukwehlisa ubungozi bokuthola i-red man syndrome, i-vancomycin kufanele inikezwe kancane phakathi nehora okungenani elilodwa.

I-Red man syndrome itholakale ukuthi yenzeka kaningi kubantu abangaphansi kweminyaka engama-40, ikakhulukazi ezinganeni.

Uma ngaphambilini wakhe i-red man syndrome uphendula i-vancomycin, maningi amathuba okuthi uzoyithuthukisa futhi ngesikhathi sokwelashwa kwe-vancomycin esizayo. Ubukhali bezimpawu abubonakali buhlukile phakathi kwabantu abake babhekana ne-red man syndrome esikhathini esidlule nabantu ababhekana nayo okokuqala.

Izimpawu ze-red man syndrome zingakhula kakhulu uma uphathwa ngezinye izidakamizwa, njenge:

• ezinye izinhlobo zama-antibiotic, njenge-ciprofloxacin noma i-rifampin
• amaphilisi ezinhlungu athile
• ukuphumula kwemisipha ethile

Lokhu kungenxa yokuthi le mithi ingagudluza amaseli omzimba afanayo ne-vancomycin, okuholele ekuthini kube nempendulo enamandla.

Isikhathi eside sokufakwa kwe-vancomycin sinciphisa ingozi yokuthi uzoba ne-red man syndrome. Uma kudingeka ukwelashwa okuningi kwe-vancomycin, ukunikezwa okuvame ukwedlula kumthamo ophansi kufanele kunikezwe.

Isigameko

Kunemibiko ehlukahlukene ngezigameko ze-red man syndrome. Kutholakale ukuthi kwenzeka kunoma yikuphi ukusuka kumaphesenti ama-5 kuye kwangama-50 abantu abaphethwe nge-vancomycin esibhedlela. Amacala amnene kakhulu angahle angabikwa ngaso sonke isikhathi, angahle abangele umehluko omkhulu.

Ukwelashwa

Ukuqhuma okuhambisana ne-red man syndrome kuvame ukuvela ngesikhathi noma ngemuva nje kokufakwa kwe-vancomycin. Lapho nje izimpawu sezithuthukile, i-red man syndrome ihlala cishe imizuzu engama-20. Kwezinye izimo, ingahlala amahora ambalwa.

Uma uhlangabezana ne-red man syndrome, udokotela wakho uzoyeka ukwelashwa kwe-vancomycin ngokushesha. Bazokunikeza isilinganiso somlomo se-antihistamine ukusiza ukuphatha izimpawu zakho. Ezimweni ezinzima kakhulu, njengalezo ezibandakanya i-hypotension, ungadinga uketshezi lwe-IV, i-corticosteroids, noma zombili.

Udokotela wakho uzolinda ukuthi izimpawu zakho zithuthuke ngaphambi kokuqala kabusha ukwelashwa kwakho kwe-vancomycin. Bazokuphatha konke okunye umthamo wakho ngesilinganiso esincane ukunciphisa ubungozi bokunye ukusabela.

Umbono

I-Red man syndrome ivame ukwenzeka lapho i-vancomycin ifakwa ngokushesha okukhulu, kepha kungenzeka lapho umuthi unikezwa neminye imizila. Uphawu oluvame kakhulu ukuqubuka okukhulu okubomvu okuqubuka emzimbeni ongaphezulu, kanye nokushaywa noma ukuzwa okushisayo.

Izimpawu zesifo somuntu obomvu azivamile ukuba zimbi kakhulu, kepha zingangakhululeki. Izimpawu ngokuvamile zihlala isikhathi esifushane futhi zingaphathwa ngama-antihistamine. Uma uke wakha i-red man syndrome phambilini, kungenzeka ukuthi uphinde uyithole. Yazisa udokotela wakho ngaphambi kokuthola ukumnika i-vancomycin uma ngabe uke waba nalokhu kusabela esikhathini esedlule.