Rimonabant ukunciphisa isisindo

-Delile

• Isetshenziswa kanjani
• Indlela yokusebenza
• Imiphumela emibi engaba khona
• Izimo

I-rimonabant eyaziwa ngezebhizinisi njenge-Acomplia noma iRedufast, ngumuthi owawusetshenziselwa ukunciphisa isisindo, ngokusebenza ohlelweni lwezinzwa oluphakathi kunciphisa ukudla.

Lo muthi usebenza ngokuvimba ama-receptors ebuchosheni nasezitho zomzimba, kunciphise ukungasebenzi kahle kohlelo lwe-endocannabinoid, okuholele ekwehleni kwesifiso sokudla, ukulawulwa kwesisindo somzimba namandla ebhalansi, kanye nokwakheka koshukela namafutha, ngaleyo ndlela kusize ukwehlisa isisindo.

Yize zisebenza kahle, ukuthengiswa kwale mithi kumisiwe ngenxa yengozi eyengeziwe yokuba nezinkinga zengqondo.

Isetshenziswa kanjani

Ukusetshenziswa kwe-rimonabant yi-1 tablet ye-20 mg nsuku zonke, ekuseni ngaphambi kokudla kwasekuseni, ngomlomo, kuthathwe kuphelele, ngaphandle kokuphulwa noma ukuhlafunwa. Ukwelashwa kufanele kuhambisane nokudla okunama-khalori aphansi kanye nokwanda kwezinga lomsebenzi womzimba.

Umthamo onconyiwe we-20 mg ngosuku akufanele weqiwe, ngenxa yengozi eyengeziwe yemicimbi emibi.

Indlela yokusebenza

URimonabant uphikisana nama-cannabinoid receptors futhi usebenza ngokuvimba uhlobo oluthile lwama-cannabinoid receptors abizwa nge-CB1, atholakala ohlelweni lwezinzwa futhi ayingxenye yohlelo olusetshenziswa umzimba ukulawula ukudla. Lawa ma-receptors akhona nakuma-adipocyte, okungamaseli wezicubu ze-adipose.

Imiphumela emibi engaba khona

Imiphumela emibi engabangelwa yilo muthi yisicanucanu nokutheleleka okuphezulu okuphefumulayo, ukungaphatheki kahle esiswini, ukuhlanza, ukuphazamiseka kokulala, ukwethuka, ukudana, ukucasuka, isiyezi, isifo sohudo, ukukhathazeka, ukulunywa, ukujuluka okweqile, amajaqamba noma ukuqubuka, ukukhathala, amabala amnyama, ubuhlungu nokuvuvukala ematendeni, ukulahleka kwememori, izinhlungu emuva, ukushintsha ukuzwela ezandleni nasezinyaweni, ukuqhuma okushisayo, umkhuhlane kanye nokuqhekeka, ukozela, ukujuluka ebusuku, izinguzunga, intukuthelo.

Ngaphezu kwalokho, izimpawu zokwethuka, ukungahlaliseki, ukuphazamiseka ngokomzwelo, imicabango yokuzibulala, ulaka noma isimilo esinolaka kungenzeka futhi.

Izimo

Njengamanje, i-ribonabant iyaphikiswa kubo bonke abantu, njengoba ihoxisiwe emakethe ngenxa yemiphumela yayo emibi.

Ngesikhathi sokuhweba kwayo, ukusetshenziswa kwayo kwakunganconyelwanga kwabesifazane abakhulelwe, ngesikhathi sokuncelisa, ezinganeni ezingaphansi kweminyaka eyi-18, abantu abane-hepatic noma i-renal insufficiency noma abanokuphazamiseka kwengqondo okungalawulwa.