Ingabe Kuphephile Ukuxuba Izitatimende notshwala?

-Delile

• Imiphumela emibi ye-Statin
• Ukuvuvukala kwesibindi
• Ubuhlungu bemisipha
• Eminye imiphumela emibi
• Ukuphuza utshwala ngenkathi usema-statins

Ukubuka konke

Kuzo zonke izidakamizwa ezehlisa i-cholesterol, ama-statins asetshenziswa kakhulu. Kodwa le mithi ayizi ngaphandle kwemiphumela engemihle. Futhi kulabo bantu abajabulela ukuphuza utshwala ngezikhathi ezithile (noma njalo), imiphumela emibi nezingozi kungahluka.

Izitatimende ziyisigaba semithi esetshenziselwa ukusiza ukwehlisa i-cholesterol. Ngokusho kwalokhu, amaphesenti angama-93 abantu abadala base-U.S abathatha umuthi we-cholesterol ngonyaka ka-2012 babethatha istin. Izitatimende ziphazamisa ukukhiqizwa komzimba kwe-cholesterol futhi zisiza ukwehlisa ama-lipoprotein (LDLs) aphansi, noma i-cholesterol embi, lapho ukudla nokuzivocavoca kungakhombisi ukuthi kuyasebenza.

Imiphumela emibi ye-Statin

Imithi kadokotela yonke iza nemiphumela engemihle, noma ingozi yemiphumela engemihle. Ngama-statins, uhlu olude lwemiphumela emibi lungenza abanye abantu bangabaze ukuthi kufanele yini ukuhweba.

Ukuvuvukala kwesibindi

Kwesinye isikhathi, ukusetshenziswa kwe-statin kungathinta impilo yesibindi. Yize kungavamile, ama-statins angakhuphula ukukhiqizwa kwe-enzyme yesibindi. Eminyakeni eminingana edlule, i-FDA yancoma ukuhlolwa kwe-enzyme ejwayelekile yeziguli ze-statin. Kepha ngoba ingozi yokulimala kwesibindi ayivelakancane, lokhu akusenjalo. Indima yesibindi ku-metabolism yotshwala kusho ukuthi labo abaphuza kakhulu bangaba sengozini enkulu, noma kunjalo.

Ubuhlungu bemisipha

Umphumela ojwayelekile kakhulu wokusetshenziswa kwe-statin ubuhlungu bemisipha nokuvuvukala. Ngokuvamile, lokhu kuzwakala njengobuhlungu noma ubuthakathaka bemisipha. Ezimweni ezimbi kakhulu, kungaholela ku-rhabdomyolysis, isimo esisongela impilo esingadala ukulimala kwesibindi, ukwehluleka kwezinso, noma ukufa.

Kuze kube ngamaphesenti angama-30 abantu abathola ubuhlungu bemisipha ngokusetshenziswa kwe-statin. Kepha cishe bonke bathola ukuthi lapho beshintshela ku-statin ehlukile, izimpawu zabo ziyaxazululeka.

Eminye imiphumela emibi

Izinkinga zokugaya ukudla, ukuqubuka, ukuqhuma, ukuphathwa kabi kweglucose egazini, nezinkinga zememori nokudideka eminye imiphumela emibi ebikiwe.

Ukuphuza utshwala ngenkathi usema-statins

Sekukonke, azikho izingozi ezithile zempilo ezihambisana nokuphuza ngenkathi usebenzisa ama-statins. Ngamanye amagama, utshwala ngeke buphazamise ngokushesha noma busebenze nama-statins emzimbeni wakho. Kodwa-ke, abaphuza ngokweqile noma labo asebevele benokulimala kwesibindi ngenxa yokuphuza ngokweqile bangaba sengozini enkulu yemiphumela emibi kakhulu.

Ngoba kokubili ukuphuza ngokweqile futhi (ngokungajwayelekile) ukusetshenziswa kwe-statin kungaphazamisa ukusebenza kwesibindi, lokhu kokubili kungabeka abantu engcupheni enkulu yezinkinga zempilo ezihlobene nesibindi.

Ukuvumelana okujwayelekile ukuthi ukuphuza iziphuzo ezingaphezu kwezimbili ngosuku kwabesilisa nesiphuzo esisodwa ngosuku kwabesifazane kungakubeka engcupheni enkulu yokuthola isifo sesibindi sotshwala kanye nemiphumela emibi ye-statin.

Uma unomlando wokuphuza ngokweqile noma ukulimala kwesibindi, ukwehluleka ukukhuluma ngesihloko lapho udokotela wakho eqala ukusikisela ukuthi ama-statins angaba yingozi. Ukwazisa udokotela wakho ukuthi ubukade ukhona noma njengamanje ungumuntu ophuza ngokweqile kuzobazisa ukuthi bafune ezinye izindlela noma babheke ukusebenza kwesibindi sakho ngezimpawu zomonakalo.