Ukuhlolwa kwe-ADPKD: Umndeni Wakho Nempilo Yakho

-Delile

• Ukubuka konke
• Ukuhlolwa kofuzo kusebenza kanjani
• Izincomo zamalungu omndeni
• Izindleko zokuhlolwa nokuhlolwa
• Ukuhlolwa kwe-aneurysm yobuchopho
• Izakhi zofuzo ze-ADPKD
• Ukutholwa kokuqala kwe-ADPKD
• Ukuthatha

Ukubuka konke

Isifo sezinso se-polyosstic esibusa kakhulu i-Autosomal (ADPKD) yisimo sofuzo esizuzwe njengefa. Lokho kusho ukuthi kungadluliswa kusuka kumzali kuye enganeni.

Uma unomzali one-ADPKD, kungenzeka ukuthi uzuze njengefa ukuguqulwa kofuzo okubanga lesi sifo. Izimpawu eziphawulekayo zalesi sifo kungenzeka zingaveli kuze kube sekugcineni empilweni.

Uma une-ADPKD, kunethuba lokuthi noma iyiphi ingane ongaba nayo nayo izokuthuthukisa lesi simo.

Ukuhlolwa kwe-ADPKD kunika amandla ukuxilongwa nokwelashwa kusenesikhathi, okunganciphisa ubungozi bezinkinga ezinkulu.

Qhubeka ufunde ukuze ufunde kabanzi ngokuhlolwa komndeni kwe-ADPKD.

Ukuhlolwa kofuzo kusebenza kanjani

Uma unomlando owaziwayo womndeni we-ADPKD, udokotela wakho angakweluleka ukuthi ucabangele ukuhlolwa kofuzo. Lokhu kuhlolwa kungakusiza ufunde ukuthi uzuze njengefa ukuguqulwa kwezakhi zofuzo okwaziwa ukuthi kubanga lesi sifo.

Ukwenza ukuhlolwa kofuzo kwe-ADPKD, udokotela wakho uzokuthumela kumeluleki wezofuzo noma oweluleka ngezakhi zofuzo.

Bazokubuza ngomlando wakho wezokwelapha womndeni ukuze ufunde ukuthi ukuhlolwa kofuzo kungafaneleka yini. Futhi zingakusiza ufunde ngezinzuzo ezingaba khona, ubungozi, nezindleko zokuhlolwa kofuzo.

Uma uthatha isinqumo sokuqhubekela phambili ngokuhlolwa kofuzo, uchwepheshe wezokunakekelwa kwempilo uzoqoqa isampula legazi lakho noma amathe. Bazothumela lesi sampula ebhodini ngokulandelana kofuzo.

Isazi sakho sezakhi zofuzo noma umeluleki wofuzo angakusiza uqonde ukuthi imiphumela yakho yokuhlolwa isho ukuthini.

Izincomo zamalungu omndeni

Uma othile emndenini wakho kutholakala ukuthi une-ADPKD, yazisa udokotela wakho.

Babuze ukuthi ngabe wena noma ezinye izingane eninazo kufanele nicabangele ukuhlolwa kwalesi sifo. Bangancoma ukuhlolwa kwe-imaging njenge-ultrasound (okuvame kakhulu), i-CT noma i-MRI, ukuhlolwa kwengcindezi yegazi, noma ukuhlolwa komchamo ukuhlola izimpawu zesifo.

Udokotela wakho futhi angakuthumela wena namalungu omndeni wakho kumeluleki wezofuzo noma oweluleka ngezakhi zofuzo. Bangakusiza ukuthi uhlole amathuba okuthi wena noma izingane zakho nizosithola lesi sifo. Zingakusiza futhi ukukala izinzuzo ezingaba khona, ubungozi, nezindleko zokuhlolwa kofuzo.

Izindleko zokuhlolwa nokuhlolwa

Ngokuya ngezindleko zokuhlola ezinikezwe njengengxenye yocwaningo lokuqala ngesihloko se-ADPKD, izindleko zokuhlolwa kofuzo zibonakala zisukela ku- $ 2,500 kuya ku- $ 5,000.

Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo ngolwazi oluthe xaxa mayelana nezindleko ezithile zokuhlolwa ongakudinga.

Ukuhlolwa kwe-aneurysm yobuchopho

I-ADPKD ingadala izinkinga ezahlukahlukene, kufaka phakathi ama-aneurysms obuchopho.

I-aneurysm yobuchopho yakha lapho umthambo wegazi ebuchosheni bakho uqhuma ngokungavamile. Uma i-aneurysm ikhala noma iqhuma, kungadala ubuchopho obusongela impilo bopha igazi.

Uma une-ADPKD, cela udokotela wakho ukuthi ngabe udinga ukuhlolwa ama-aneurysms obuchopho. Cishe bazokubuza ngomlando wakho wezempilo nowomndeni wezinhlungu zekhanda, ama-aneurysms, ukuphuma kwegazi lobuchopho, nokushaya uhlangothi.

Ngokuya ngomlando wakho wezokwelapha nezinye izinto ezinobungozi, udokotela wakho angakweluleka ukuthi uhlolwe ama-aneurysms. Ukuhlola kungenziwa ngokuhlolwa kwe-imaging njenge-magnetic resonance angiography (MRA) noma i-CT scan.

Udokotela wakho angakusiza nokuthi ufunde ngezimpawu nezimpawu ezingaba khona ze-aneurysm yobuchopho, kanye nezinye izinkinga ezingaba khona ze-ADPKD, ezingakusiza uqaphele izinkinga uma zikhula.

Izakhi zofuzo ze-ADPKD

I-ADPKD ibangelwa ukuguqulwa kwezakhi zofuzo ku-PKD1 noma ku-PKD2 gene. Lezi zofuzo zinikeza umzimba wakho iziyalezo zokwenza amaprotheni asekela ukukhula kwezinso nokusebenza okufanele.

Cishe amaphesenti ayi-10 amacala we-ADPKD abangelwa ukuguquguquka okuzenzakalelayo kofuzo kumuntu ongenawo umlando womndeni wesifo. Emacaleni amaphesenti angama-90 asele, abantu abane-ADPKD bathola ikhophi elingavamile lohlobo lwe-PKD1 noma lwe-PKD2 kumzali.

Umuntu ngamunye unamakhophi amabili wezakhi zofuzo ze-PKD1 ne-PKD2, enekhophi eyodwa yofuzo ngalunye olutholwe kumzali ngamunye.

Umuntu udinga ukuthola ifa elilodwa lekhophi ye-PKD1 noma i-PKD2 ukuthola i-ADPKD.

Lokho kusho ukuthi uma unomzali oyedwa onesifo, unethuba elingamaphesenti angama-50 lokuzuza ikhophi yofuzo oluthintekile nokuthuthukisa i-ADPKD. Uma unabazali ababili abanalesi sifo, amathuba akho okuba nalesi sifo ayanda.

Uma une-ADPKD futhi umlingani wakho engenayo, izingane zakho zizoba nethuba elingamaphesenti angama-50 lokuthola ifa lohlobo oluthintekile nokuthuthukisa lesi sifo. Uma nobabili ninozakwenu une-ADPKD, amathuba ezingane zakho zokuthuthukisa lesi sifo ayanda.

Uma wena noma ingane yakho ninamakhophi amabili ohlobo oluthintekile, kungahle kube necala elibi kakhulu le-ADPKD.

Lapho ikhophi eliguqukile lohlobo lwe-PKD2 lubangela i-ADPKD, ijwayele ukudala isimo esibi kakhulu sesifo kunangesikhathi kuguquka kwesakhi sofuzo se-PKD1 kubangela isimo.

Ukutholwa kokuqala kwe-ADPKD

I-ADPKD yisifo esingelapheki esenza ukuthi ama-cysts akheke ezinso zakho.

Ungahle ungaboni zimpawu kuze kube yilapho ama-cysts eba maningi noma makhulu ngokwanele ukudala ubuhlungu, ingcindezi, noma ezinye izimpawu.

Ngaleso sikhathi, lesi sifo kungenzeka ukuthi sesivele sidala ukulimala kwezinso noma ezinye izinkinga ezingase zibe nzima.

Ukuhlolwa ngokucophelela nokuhlolwa kungasiza wena nodokotela wakho ukuthola nokwelapha lesi sifo ngaphambi kokuba kuvele izimpawu noma izinkinga ezinkulu.

Uma unomlando womndeni we-ADPKD, yazisa udokotela wakho. Bangakudlulisela kumeluleki wezofuzo noma oweluleka ngezakhi zofuzo.

Ngemuva kokuhlola umlando wakho wezokwelapha, udokotela wakho, u-geneticist, noma umeluleki wezofuzo angancoma okukodwa noma ngaphezulu kwalokhu okulandelayo:

• ukuhlolwa kofuzo ukuhlola ukuguquka kwezakhi zofuzo okudala i-ADPKD
• ukuhlolwa kwe-imaging ukuhlola ama-cysts ezinso zakho
• ukuqapha umfutho wegazi ukuhlola umfutho wegazi ophakeme
• ukuhlolwa komchamo ukubheka izimpawu zesifo sezinso

Ukuhlolwa okusebenzayo kungavumela ukuxilongwa nokwelashwa ngaphambi kwesikhathi kwe-ADPKD, okungasiza ekuvimbeleni ukwehluleka kwezinso noma ezinye izinkinga.

Udokotela wakho cishe uzoncoma ezinye izinhlobo zokuhlolwa kokuqapha okuqhubekayo ukuhlola impilo yakho yonke futhi afune izimpawu zokuthi i-ADPKD ingaqhubeka. Isibonelo, bangakweluleka ukuthi uhlolwe igazi njalo ukuze ubheke impilo yezinso zakho.

Ukuthatha

Amacala amaningi we-ADPKD akhula kubantu abazuze ukuguqulwa kwezakhi zofuzo komunye wabazali babo. Ngakolunye uhlangothi, abantu abane-ADPKD bangahle badlulisele isakhi sofuzo ezinganeni zabo.

Uma unomlando womndeni we-ADPKD, udokotela wakho angancoma ukuhlolwa kwe-imaging, ukuhlolwa kofuzo, noma kokubili ukuhlola lesi sifo.

Uma une-ADPKD, udokotela wakho angancoma nokuhlola izingane zakho ngalesi simo.

Udokotela wakho futhi angancoma ukuhlolwa okujwayelekile kwezinkinga.

Khuluma nodokotela wakho ukuze ufunde kabanzi ngokuhlola nokuhlolela i-ADPKD.