I-Somatropin: iyini, yenzelwa ini nemiphumela engemihle

-Delile

• Yenzelwe ini
• Isetshenziswa kanjani
• Imiphumela emibi engaba khona
• Ngubani ongafanele asebenzise

I-Somatropin ngumuthi oqukethe i-hormone yokukhula komuntu, ebalulekile ekukhuleni kwamathambo nemisipha, esebenza ngokukhuthaza ukukhula kwamathambo, ukwandisa usayizi nenani lamaseli emisipha nokunciphisa ukugcwala kwamafutha emzimbeni.

Lo muthi ungatholakala emakhemisi nasezitolo zezidakamizwa ezinamagama okuhweba iGenotropin, iBiomatrop, iHormotrop, iHumatrope, iNorditropin, iSaizen noma iSomatrop, futhi ithengiswa kuphela ngencwadi kadokotela.

I-Somatropin ngumuthi ojojwayo futhi kufanele usetshenziswe ngokuyalelwa ngudokotela.

Yenzelwe ini

I-Somatropin isetshenziselwa ukwelapha ukuntula kokukhula ezinganeni nakubantu abadala ngokushoda kwe-hormone yokukhula yemvelo. Lokhu kufaka phakathi abantu abanesimo esifushane ngenxa yeNoonan syndrome, i-Turner syndrome, i-Prader-Willi syndrome noma isiqu esifushane ngesikhathi sokuzalwa ngaphandle kokululama kokukhula.

Isetshenziswa kanjani

I-Somatropin kufanele isetshenziswe ngokuncoma kukadokotela futhi isetshenziswe emisipheni noma ngaphansi kwesikhumba, futhi umthamo kufanele njalo ubalwe ngudokotela, ngokusho kwecala ngalinye. Kodwa-ke, ngokuvamile umthamo onconyiwe uwukuthi:

• Abantu abadala kuze kube yiminyaka engama-35: isilinganiso samazinga okuqala sisuka ku-0.004 mg siye ku-0.006 mg we-somatropin nge-kg yesisindo somzimba esisetshenziswa nsuku zonke ngaphansi kwesikhumba ngaphansi kwesikhumba. Lo mthamo ungakhuphuka ufike ku-0.025 mg ngekhilogremu ngayinye yesisindo somzimba ngosuku osetshenziswe ngendlela engaphansi;
• Abantu abadala abaneminyaka engama-35 nangaphezulu: isilinganiso sokuqala sisuka ku-0,004 mg siye ku-0,006 mg we-somatropin ngekhilogremu ngayinye yesisindo somzimba nsuku zonke esisetshenziswa ngaphansi kwesikhumba ngaphansi, futhi singakhuphuka size sifike ku-0.0125 mg ngekhilogremu ngalinye lesisindo somzimba ngosuku;
• Izingane: isilinganiso sokuqala sisuka ku-0.024 mg siye ku-0.067 mg we-somatropin nge-kg yesisindo somzimba esisetshenziswa nsuku zonke ngaphansi kwesikhumba ngaphansi kwesikhumba. Ngokuya ngecala, udokotela angakhombisa futhi u-0.3 mg kuya ku-0.375 mg nge-kg yesisindo somzimba masonto onke, ehlukaniswe ngamanani we-6 kuye ku-7, asetshenziswe usuku ngalunye ngaphansi kwesikhumba.

Kubalulekile ukushintsha izindawo phakathi komjovo ngamunye ongaphansi kwesikhumba osetshenzisiwe ngaphansi kwesikhumba, ukugwema ukutholakala kokuphendula endaweni yomjovo njengokubomvu noma ukuvuvukala.

Imiphumela emibi engaba khona

Eminye yemiphumela emibi kakhulu engahle yenzeke ngenkathi welashwa nge-somatropin yikhanda, ubuhlungu bemisipha, ubuhlungu endaweni okujovolelwa kuyo, ubuthakathaka, ukuqina kwesandla noma konyawo noma ukugcinwa koketshezi.

Ngaphezu kwalokho, kungaba nokwanda kwe-insulin ukumelana, kubangele isifo sikashukela ngokwanda kweglucose yegazi kanye nokuba khona kwe-glucose emchameni.

Ngubani ongafanele asebenzise

I-Somatropin akufanele isetshenziswe ngabesifazane abakhulelwe noma abancelisayo, abantu abane-tumor ebulalayo noma isiqu esifushane esibangelwa isimila sobuchopho kanye nabantu abalwa ne-somatropin noma enye ingxenye yefomula.

Ngaphezu kwalokho, kubantu abanesifo sikashukela sohlobo 2, i-hypothyroidism noma i-psoriasis engalashwa, i-somatropin kufanele isetshenziswe ngokuqapha futhi kufanele ihlolwe kahle ngudokotela ngaphambi kokuyisebenzisa.