Ukumisa iMetformin: Kulungile Nini?

-Delile

• Isebenza kanjani i-metformin?
• Imiphumela emibi nezingozi ze-metformin
• Imiphumela emibi ejwayelekile
• Eminye imiphumela emibi
• I-Hypoglycemia
• I-Lactic acidosis
• Kulungile nini ukuyeka ukuthatha i-metformin?
• Ongakwenza

NgoMeyi 2020, okunconywayo ukuthi abanye abenzi be-metformin enwetshiwe bakhiphe amanye amaphilisi abo emakethe yase-U.S. Lokhu kungenxa yokuthi izinga elingamukeleki le-carcinogen (i-agent ebangela umdlavuza) itholakale kwamanye amaphilisi e-metformin akhululwa isikhathi eside. Uma okwamanje uthatha lo muthi, shayela umhlinzeki wakho wezokunakekelwa kwempilo. Bazokweluleka ngokuthi ngabe kufanele uqhubeke nokudla imishanguzo yakho noma uma udinga incwadi kadokotela entsha.

Imithi ejwayelekile emhlabeni wonke yokwelapha isifo sikashukela yi-metformin (Glumetza, Riomet, Glucophage, Fortamet). Kungasiza ukulawula ushukela ophakeme wegazi kubantu abanesifo sikashukela sohlobo 2. Kutholakala kwifomu yethebhulethi noma uketshezi olucacile olithatha ngomlomo ngokudla.

Uma uthatha i-metformin ekwelapheni uhlobo lwesifo sikashukela esingu-2, kungenzeka ukuthi ume. Ungahle ukwazi ukuphatha isimo sakho ngokwenza izinguquko ezithile zendlela yokuphila, njengokugcina isisindo esinempilo nokuvivinya umzimba ngokwengeziwe.

Funda ukuze ufunde kabanzi mayelana ne-metformin nokuthi kungenzeka yini uyeke ukuyithatha.

Ngaphambi kokuba uyeke ukuthatha i-metformin, khuluma nodokotela wakho ukuze ubone ukuthi lesi isinyathelo esifanele okufanele usithathe ekulawuleni isifo sikashukela.

Isebenza kanjani i-metformin?

I-Metformin ayiphathi imbangela eyinhloko yesifo sikashukela. Iphatha izimpawu zesifo sikashukela ngokwehlisa ushukela wegazi, noma i-glucose, ngo:

• ukunciphisa ukukhiqizwa kwesibindi kwe-glucose
• ukuncipha kokuncipha kwe-glucose emathunjini
• ukwenza ngcono ukuzwela kwe-insulin ezicutshini zomngcele, kukhuphuke ukuthathwa kwezicubu kanye nokusetshenziswa kwe-glucose

IMetformin iyasiza ngezinye izinto ngaphezu kokuthuthukisa ushukela wegazi.

Lokhu kufaka phakathi:

• ukwehlisa ama-lipids, okuholela ekwehleni kwamazinga we-triglyceride egazi
• ukuncipha kwe-cholesterol "ephansi" ye-lipoprotein (LDL)
• ukwandisa “okuhle” i-high-density lipoprotein (HDL) cholesterol
• mhlawumbe ukunciphisa ukudla kwakho, okungaholela ekunciphiseni isisindo esilinganiselwe

Imiphumela emibi nezingozi ze-metformin

Ngenxa yezingozi zayo kanye nemiphumela emibi, i-metformin ayiphephile kuwo wonke umuntu. Akunconyiwe uma unomlando we:

• ukuphazamiseka kokusebenzisa izidakamizwa
• isifo sesibindi
• izinkinga ezinzima zezinso
• izinkinga ezithile zenhliziyo

Uma njengamanje uthatha i-metformin futhi ube nemiphumela engemihle, ungahle ubheke ezinye izindlela zokwelashwa.

Imiphumela emibi ejwayelekile

Imiphumela emibi kakhulu yizinhlungu zekhanda nezinkinga zokugaya ukudla ezingafaka:

• isifo sohudo
• ukuhlanza
• isicanucanu
• isilungulela
• amajaqamba esiswini
• igesi
• ukunambitheka kwensimbi
• ukulahlekelwa isifiso sokudla

Eminye imiphumela emibi

Kwezinye izimo, i-metformin iholela ekumungeni kabi i-vitamin B-12. Lokho kungaholela ekushodeni kukavithamini B-12, yize lokhu kwenzeka kuphela ngemuva kokusebenzisa isikhathi eside umuthi.

Njengendlela yokuqapha, udokotela wakho uzohlola amazinga akho e-B-12 njalo eminyakeni eyodwa kuya kwemibili ngenkathi uthatha i-metformin.

Ukuthatha i-metformin nakho kungaholela ekulahlekelweni isifiso sokudla, okungadala ukuncipha kwesisindo esincane. Kepha ukuthatha lo muthi ngeke kuholele ekutholeni isisindo.

Kukhona neminye imiphumela emibi ongase uhlangane nayo, kufaka phakathi i-hypoglycemia ne-lactic acidosis.

I-Hypoglycemia

I-Hypoglycemia, noma ushukela wegazi ophansi, kungenzeka kusukela i-metformin yehlisa ushukela wegazi. Kubalulekile ukuqapha ushukela wegazi lakho njalo ukuze udokotela wakho akwazi ukulungisa isilinganiso sakho ngokuya ngamazinga akho.

I-Hypoglycemia ngenxa ye-metformin ingumphumela wecala ongajwayelekile.

Ushukela wegazi ophansi kungenzeka kakhulu uma uthatha i-metformin nezinye izidakamizwa zesifo sikashukela noma i-insulin.

I-Lactic acidosis

I-Metformin ingadala isimo esisongela impilo esibizwa nge-lactic acidosis. Abantu abane-lactic acidosis banenqwaba yezinto ezibizwa nge-lactic acid egazini labo futhi akufanele bathathe i-metformin.

Lesi simo siyingozi kakhulu futhi siyabulala kaningi. Kepha lokhu kungumphumela wecala ongajwayelekile futhi kuthinta ngaphansi kuka-1 kubantu abayi-100,000 abathatha i-metformin.

I-Lactic acidosis kungenzeka ukuthi yenzeke kubantu abanesifo sezinso. Tshela udokotela wakho uma uke waba nezinkinga zezinso.

Kulungile nini ukuyeka ukuthatha i-metformin?

I-Metformin ingaba yingxenye ebalulekile yohlelo olusebenzayo lokwelashwa kwesifo sikashukela. Kodwa ukunciphisa umthamo we-metformin noma ukuwumisa ngokuphelele kuphephile kwezinye izimo uma isifo sikashukela silawulwa.

Uma ufuna ukuyeka ukuthatha imishanguzo yesifo sikashukela, khuluma nodokotela wakho noma umhlinzeki wezokunakekelwa kwempilo mayelana nokuthi yiziphi izinyathelo okudingeka uzithathe ukwenza kanjalo.

Wonke umuntu onesifo sikashukela angazuza ngokushintsha imikhuba ethile yokuphila, ngisho nalabo abathatha imishanguzo.

Ukwehla kwesisindo, ukudla kangcono, nokuzivocavoca umzimba kuyizindlela ezingcono kakhulu zokusiza ukunciphisa i-glucose yegazi ne-A1C. Uma ukwazi ukuphatha lokhu ngoshintsho lwendlela yokuphila, ungakwazi ukuyeka ukuthatha i-metformin noma ezinye izidakamizwa zesifo sikashukela.

Ngokusho kochwepheshe be-American Diabetes Association, imvamisa udinga ukuhlangabezana nalezi zindlela ezilandelayo ngaphambi kokuba uyeke ukuthatha imishanguzo yesifo sikashukela:

• I-A1C yakho ingaphansi kwamaphesenti ayi-7.
• I-glucose yakho yegazi yokuzila ekuseni ingaphansi kwama-milligram ayi-130 nge-deciliter (mg / dL) ngayinye.
• Izinga lakho le-glucose egazini ngokungahleliwe noma ngemuva kokudla lingaphansi kwe-180 mg / dL.

Kuyingozi ukuyeka ukuthatha i-metformin uma ungahlangabezani nalezi zindlela. Futhi khumbula ukuthi lezi zindlela zingashintsha ngokuya ngeminyaka yakho, impilo yonke, nezinye izinto. Ngakho-ke, kubalulekile ukukhuluma nodokotela wakho ngaphambi kokushintsha uhlelo lwakho lwe-metformin.

Ongakwenza

I-Metformin ingasiza ukuvimbela izinkinga zempilo zesikhathi eside ezivela kuhlobo lwesibili sikashukela. Kepha ungakwazi ukuyeka ukuyithatha uma udokotela wakho ecabanga ukuthi ungagcina ushukela wegazi lakho ngaphandle kwawo.

Ungahle wehlise ngempumelelo futhi uphathe ushukela wegazi lakho ngaphandle kwemithi ngokwenza izinguquko kwimpilo yakho njengokulandelayo:

• ukugcina isisindo esinempilo
• ukuvivinya umzimba ngokwengeziwe
• ukunciphisa ukudla kwakho kwama-carbohydrate
• ukuguqula ukudla kwakho kufake ama-carbohydrate aphansi-glycemic
• ukuyeka ukubhema ugwayi nganoma iyiphi indlela
• ukuphuza kancane noma ukungaphuzi nhlobo

Kubalulekile futhi ukuthola ukwesekwa. I-dietitian ebhalisiwe, umqeqeshi womuntu siqu, noma iqembu lontanga angathuthukisa amathuba akho okunamathela kule mikhuba enempilo.

Vakashela i-American Diabetes Association ngosizo oluku-inthanethi nolwasendaweni emphakathini wakho.