I-Topiramate: iyini nemiphumela engemihle

-Delile

• Isetshenziswa kanjani
• 1. Ukwelashwa okuncedisayo kwesifo sokuwa
• 2. Ukwelashwa nge-Epilepsy monotherapy
• 3. Migraine prophylaxis
• Ngubani ongafanele asebenzise
• Imiphumela emibi engaba khona

I-Topiramate iyikhambi elwa nomuthi elaziwa ngokuthi yi-Topamax, elisebenza ohlelweni lwezinzwa oluphakathi, oluzinzisa imizwa, futhi livikele ubuchopho. Lo muthi ukhonjisiwe ekwelashweni kwesifo sokuwa kubantu abadala nasezinganeni, ekwelapheni izinkinga ezihambisana neLennox-Gastaut Syndrome kanye nokwelashwa kwe-prophylactic ye-migraine.

I-Topiramate ingathengwa emakhemisi, ngentengo engaba ngama-reais angama-60 kuye kwangama-300, kuya ngomthamo, usayizi wokupakisha nomkhiqizo womuthi, futhi kukhona nethuba lokukhetha okujwayelekile.

Isetshenziswa kanjani

Ukwelashwa kufanele kuqalwe ngomthamo ophansi, okufanele wenyuswe kancane kancane, kuze kufike umthamo ofanele.

1. Ukwelashwa okuncedisayo kwesifo sokuwa

Umthamo omncane osebenzayo ngu-200 mg ngosuku, kuze kufike ku-1600 mg ngosuku, okubhekwa njengomthamo omkhulu. Ukwelashwa kufanele kuqalwe ngo-25 kuye ku-50 mg, okwenziwe kusihlwa, isonto elilodwa. Ngemuva kwalokho, ngezikhathi ezithile zamaviki ama-1 noma ama-2, umthamo kufanele ukhuphuke ngo-25 kuye ku-50 mg / ngosuku futhi uhlukaniswe ngemithamo emibili.

Ezinganeni ezineminyaka engaphezu kwengu-2 ubudala, umthamo wansuku zonke onconywayo ungo-5 kuye ku-9 mg / kg ngosuku, uhlukaniswe waba yiminyango emibili.

2. Ukwelashwa nge-Epilepsy monotherapy

Lapho eminye imishanguzo yokulwa nesifo sokuwa isuswa ohlelweni lokwelapha, ukuze kugcinwe ukwelashwa nge-topiramate njenge-monotherapy, imiphumela engaba nayo ekulawuleni ukuquleka kufanele icatshangelwe, yeluleke, uma kungenzeka, ukumiswa kancane kancane kokwelashwa kwangaphambilini.

Ezinganeni ezineminyaka engaphezu kwengu-2 ubudala, isilinganiso sokuqala sihluka kusuka ku-0.5 kuye ku-1 mg / kg ngosuku, kusihlwa, ngesonto. Ngemuva kwalokho, umthamo kufanele ukhuphuke ngo-0.5 kuye ku-1 mg / kg ngosuku, ngezikhathi ezithi 1 kuya ku-2 amasonto, uhlukaniswe waba yiminyango emibili.

3. Migraine prophylaxis

Ukwelashwa kufanele kuqalwe nge-25 mg kusihlwa isonto elilodwa. Lo mthamo kufanele ukhuliswe ngo-25 mg / ngosuku, kanye ngesonto, kuze kufike ku-100 mg / ngosuku, kuhlukaniswe kwaba yiminyango emibili.

Ngubani ongafanele asebenzise

I-Topiramate akufanele isetshenziswe ngabantu abazwela ngokweqile ezingxenyeni zefomula, kwabesifazane abakhulelwe noma abesifazane abasola ukuthi bakhulelwe.

Imiphumela emibi engaba khona

Eminye yemiphumela emibi kakhulu engahle yenzeke ngesikhathi sokwelashwa nge-topiramate ukozela, isiyezi, ukukhathala, ukucasuka, ukwehlisa isisindo, ukucabanga okungasheshi, ukushoshozela, ukubona kabili, ukuxhumeka okungavamile, isicanucanu, i-nystagmus, ukunqena, i-anorexia, ukukhuluma kanzima, ukubona okufiphele , ukuncipha kwesifiso sokudla, inkumbulo engasebenzi kahle nohudo.