I-Toujeo vs. Lantus: Aqhathanisa Kanjani Lawa ma-Insulins asebenza isikhathi eside?

-Delile

• Amaqiniso asheshayo kaToujeo noLantus
• Ithebula lokuqhathanisa
• Imithamo yeToujeo neLantus
• Amafomu weToujeo neLantus
• Ukusebenza kweToujeo neLantus
• Imiphumela emibi yeToujeo neLantus
• Izindleko zeToujeo neLantus
• Okubalulekile

Ukubuka konke

UToujeo noLantus bangama-insulin asebenza isikhathi eside asetshenziselwa ukuphatha isifo sikashukela. Angamagama omkhiqizo we-generic insulin glargine.

ILantus ibingelinye lama-insulins asebenza isikhathi eside esetshenziswa kakhulu selokhu atholakala ngonyaka ka-2000. IToujeo yintsha kakhulu, futhi yangena kuphela emakethe ngo-2015.

Funda ukuze ufunde ukuthi lawa ma-insulini amabili aqhathaniswa kanjani ngokwezindleko, ukusebenza kahle ekwehliseni i-glucose yegazi, kanye nemiphumela emibi.

Amaqiniso asheshayo kaToujeo noLantus

UToujeo noLantus bobabili bangama-insulins asebenza isikhathi eside asetshenziselwa ukwelapha abantu abanesifo sikashukela esincike ku-insulin. Ngokungafani ne-insulin esebenza ngokushesha oyithatha ngaphambi noma ngemuva kokudla noma isidlo, i-insulin esebenza isikhathi eside ithatha isikhathi esiningi ukungena egazini. Kusebenza ukulawula amazinga we-glucose egazini lakho amahora angama-23 noma ngaphezulu.

Kokubili iToujeo neLantus kwenziwa yiSanofi, kepha kunezici ezithile ezihlukanisayo phakathi kwalokhu okubili. Umehluko omkhulu ukuthi iToujeo igxile kakhulu, okwenza ivolumu yomjovo incane kakhulu kuneLantus.

Ngokuya ngemiphumela engemihle, into ebalulekile okufanele uyicabangele ukuthi iToujeo ingahle inikeze ingozi encane ye-hypoglycemia, noma i-glucose ephansi yegazi, kuneLantus, ngoba isiza ukugcina amazinga kashukela egazini ehambelana kakhulu.

Ithebula lokuqhathanisa

Ngenkathi izindleko nezinye izinto zingadlala esinqumweni sakho, nasi isifinyezo sokuqhathaniswa kwama-insulins amabili:

Imithamo yeToujeo neLantus

Ngenkathi iLantus iqukethe amayunithi ayi-100 ngemililitha, iToujeo igxilwe kathathu ngaphezulu, ikhipha amayunithi angama-300 ngemililitha (U100 ngokuqhathanisa no-U300, ngokulandelana) ketshezi. Kodwa-ke, lokhu akusho ukuthi kufanele uthathe umthamo ophansi weToujeo kunalokho ongakuthatha kuLantus.

Imithamo ingashintsha ngezinye izizathu, njengokushintshashintsha kwesisindo noma kokudla, kepha imithamo yeToujeo neLantus kufanele ifane noma isondele kakhulu. Eqinisweni, ucwaningo lukhombisa ukuthi abantu bagcina bedinga cishe ama-10 kuya ku-15 amaphesenti ngaphezulu kweToujeo kuneLantus ukugcina ukufundwa okufanayo kwe-glucose yokuzila ukudla.

Udokotela wakho uzokwazisa ukuthi imuphi umthamo olungele wena. IToujeo izokwenza kuphela ukuvela ukuba yivolumu encane ngaphakathi kwepeni ngoba icwiliswe kunani elincane loketshezi lwenkampani yenethiwekhi. Kufana nokuthola inani elilinganayo le-caffeine esithombeni esincane se-espresso noma i-latte enkulu.

Uma udinga umthamo omkhulu we-insulin, ungadinga imijovo embalwa ngeToujeo kunaleyo obuyodinga ngeLantus, ngoba ipeni laseToujeo lingabamba okuningi.

Amafomu weToujeo neLantus

Isithako esisebenzayo kuzo zombili iLantus naseToujeo yi-insulin glargine, i-insulin yokuqala eyasungulwa ukuze isebenze isikhathi eside emzimbeni. Zombili zilethwa ngezibaya ezilahlwayo ze-insulin, eziqeda isidingo sokukala imithamo nokugcwalisa imijovo. Umane ushayele ipeni kumthamo wakho, ucindezele ipeni emzimbeni wakho, bese wenza kusebenze ukulethwa ngokuchofoza okukodwa.

Izibaya zeToujeo neLantus zombili zibizwa ngeSoloStar futhi zenzelwe ukwenza izibalo zomthamo zibe lula. Umkhiqizi uthi amandla okujova nobude bawo bobabili buphansi kuToujeo kunalapho benoLantus.

ILantus iyatholakala nasezimbizeni zokusetshenziswa ngamasirinji. UToujeo akayona.

Zombili zingafakwa esiqandisini uma zingavulwa. ILantus nayo ingagcinwa ekamelweni lokushisa. Uma sekuvuliwe, iLantus ingahlala izinsuku ezingama-28 ekamelweni lokushisa, kanti iToujeo ingayenza izinsuku ezingama-42.

Ukusebenza kweToujeo neLantus

Kokubili iToujeo neLantus behlisa ngempumelelo izinombolo ze-hemoglobin A1C, ezimele isilinganiso seglucose yegazi ngokuhamba kwesikhathi. Ngenkathi lezo zilinganiso zingase zifane kunoma iyiphi ifomula, uSanofi uthi iToujeo inikeza amazinga kashukela egazini angaguquki usuku lonke, okungaholela ekwehleni nokwehla okumbalwa kumandla, imizwa, ukuqapha, kanye namazinga endlala.

ILantus iqala ukusebenza ihora elilodwa kuya kwamathathu ngemuva kokujova. Kuthatha amahora ayi-12 ukuthi uhhafu womthamo ususwe emzimbeni, obizwa ngokuthi yi-half-life. Ifinyelela esimweni esizinzile ngemuva kwezinsuku ezimbili noma ezine zokusetshenziswa. Isimo esimile sisho ukuthi inani lemithi eliza emzimbeni lilingana nenani eliphumayo.

IToujeo ibonakala ihlala isikhathi eside emzimbeni, kodwa futhi ingena emzimbeni kancane. Kuthatha amahora ayisithupha ukuqala ukusebenza nezinsuku ezinhlanu zokusetshenziswa ukufinyelela esimweni esizinzile. Ingxenye yokuphila kwayo ingamahora ayi-19.

Imiphumela emibi yeToujeo neLantus

Ucwaningo lukhombisa ukuthi iToujeo ingahlinzeka ngamazinga kashukela egazini angaguquki kuneLantus, enganciphisa amathuba kashukela aphansi egazini. Eqinisweni, ngokocwaningo oluthile, labo abasebenzisa iToujeo bancipha kakhulu ngamaphesenti angama-60 okuba nezigameko ezinzima ze-hypoglycemic kunabantu abathatha iLantus. Ehlangothini le-flip, uma uthatha i-Lantus, ungahle ube mancane amathuba okuthi uthole ukutheleleka okuphezulu okuphefumulayo kunokuba ubungasebenzisa njengomsebenzisi we-Toujeo.

Noma kunjalo, ushukela wegazi ophansi ungumphumela omubi kakhulu wokuthatha iToujeo, iLantus, noma iyiphi ifomula ye-insulin. Ezimweni ezimbi kakhulu, ushukela wegazi ophansi ungasongela impilo.

Eminye imiphumela emibi ingafaka:

• ukuzuza kwesisindo
• ukuvuvukala ezandleni, izinyawo, izingalo, noma imilenze

Ukuphendula kwesayithi lokujova kungahle kuqukethe:

• ukulahleka kwevolumu yamafutha noma i-indent esikhumbeni
• ububomvu, ukuvuvukala, ukulunywa, noma ukushisa lapho usebenzise khona ipeni

Le miphumela imvamisa iba mncane futhi akufanele ihlale isikhathi eside. Uma ziphikelela noma zibuhlungu ngokungavamile, khuluma nodokotela wakho noma usokhemisi.

Izindleko zeToujeo neLantus

Ukuseshwa kwamakhemisi amaningana online kukhombisa ukuthi iLantus ibiza ngentengo engu- $ 421 yamapeni amahlanu, okungaphezudlwana kwamapeni amathathu alinganayo eToujeo ngo- $ 389.

Kubalulekile ukuthi uhlole nenkampani yakho yomshuwalense ukuthola ukuthi bazokhokha malini nokuthi badinga ukuthi ukhokhe malini. Ngemuva kokutholakala komshuwalense, kungenzeka ukuthi iToujeo ingakubiza inani elifanayo noma ngaphansi kukaLantus.

Bheka izinhlobo ezingabizi kakhulu, ezijwayelekile ze-insulin, ebizwa ngama-biosimilars. Ilungelo lobunikazi likaLantus liphelelwe isikhathi ngo-2015. Kunomuthi "wokulandela", owenziwe njenge-biosimilar, emakethe manje ebizwa.

Khumbula ukubuza nomshwalense wakho, futhi, ngoba bangagcizelela ukuthi usebenzise inguqulo engabizi kakhulu yanoma iyiphi i-insulin okhetha ukuyisebenzisa. Lezi yizici ongaxoxa ngazo nosokhemisi wakho, ozokwazi kaningi ukungena nokuphuma komshwalense wakho kadokotela.

Okubalulekile

UToujeo noLantus bangama-insulins amabili asebenza isikhathi eside afana kakhulu ngezindleko, ukusebenza kahle, ukulethwa, kanye nemiphumela emibi. Uma njengamanje uthatha i-Lantus, futhi ujabulile ngemiphumela, kungahle kungabikho sizathu sokushintsha.

UToujeo anganikela ngezinzuzo ezithile uma uhlangabezana nokuguquguquka koshukela wegazi noma uneziqephu ezivame kakhulu ze-hypoglycemic. Ungase futhi ucabangele ukushintsha uma ukhathazwa ngokujova ivolumu yoketshezi edingwa yiLantus. Ngakolunye uhlangothi, uma ukhetha imijovo, unganquma ukuhlala eLantus.

Udokotela wakho angakusiza ukuthi udlulise izinqumo mayelana nokuthi iyiphi i-insulin ongayithatha, kodwa ngaso sonke isikhathi hlola inkampani yakho yomshwalense ukuze uqiniseke ukuthi kunengqondo ukubiza izindleko.