Kungani iTroponin Ibalulekile?

-Delile

• Amazinga ajwayelekile we-troponin
• Izimbangela eziphakeme ze-troponin
• Yini ongayilindela ngesikhathi sokuhlolwa
• Umbono

Yini i-troponin?

Ama-troponins amaphrotheni atholakala emisipheni yenhliziyo namathambo. Lapho inhliziyo yonakele, ikhiphela i-troponin egazini. Odokotela balinganisa amazinga akho e-troponin ukuthola ukuthi uhlangabezana nokuhlaselwa yinhliziyo noma cha. Lokhu kuhlolwa kungasiza nodokotela ukuthi bathole ukwelashwa okungcono kakhulu ngokushesha.

Phambilini odokotela bebesebenzisa okunye ukuhlolwa kwegazi ukuthola ukuhlaselwa yinhliziyo. Lokhu bekungasebenzi, kepha, ngoba izivivinyo bezingazweli ngokwanele ukuthola konke ukuhlaselwa. Ziphinde zabandakanya izinto ezazingaqondile ngokwanele emisipheni yenhliziyo. Ukuhlaselwa yisifo senhliziyo okuncane kwashiya umkhondo ekuhlolweni kwegazi.

I-Troponin ibucayi kakhulu. Ukukala amazinga we-troponin yenhliziyo egazini kuvumela odokotela ukuthi bathole ukuhlaselwa yinhliziyo noma ezinye izimo ezihlobene nenhliziyo ngempumelelo, futhi banikeze ukwelashwa ngokushesha.

Amaprotheni e-Troponin ahlukaniswe ama-subunits amathathu:

• I-troponin C (TnC)
• I-troponin T (TnT)
• I-troponin I (TnI)

Amazinga ajwayelekile we-troponin

Kubantu abaphilile, amazinga e-troponin aphansi ngokwanele ukuthi angatholakali. Uma uhlangabezane nobuhlungu besifuba, kodwa amazinga e-troponin asephansi amahora angu-12 ngemuva kokuqala kobuhlungu besifuba, amathuba okuhlaselwa yinhliziyo ngokungalindelekile.

Izinga eliphakeme le-troponin yifulegi elibomvu ngokushesha. Ukuphakama kwesibalo, i-troponin - ikakhulukazi i-troponin T kanye nami-ikhishwe egazini futhi kukhuphuka namathuba okulimala kwenhliziyo. Amazinga weTroponin angakhuphuka kungakapheli amahora we-3-4 ngemuva kokuthi inhliziyo ilimele futhi angahlala ephezulu kuze kube yizinsuku eziyi-14.

Amazinga eTroponin alinganiswa ngama-nanograms ngemililitha ngayinye. Amazinga ajwayelekile awela ngaphansi kwama-99th percentile ekuhlolweni kwegazi. Uma imiphumela ye-troponin ingaphezulu kwaleli zinga, kungaba inkomba yokulimala kwenhliziyo noma isifo senhliziyo. Kodwa-ke, kusikisela ukuthi abesifazane bangathola ukulimala kwenhliziyo kusukela ekuhlaselweni yinhliziyo emazingeni angaphansi kwesilinganiso "esivamile" samanje. Lokhu kusho ukuthi ngokuzayo, lokho okubhekwa njengokujwayelekile kungahluka kwabesilisa nabesifazane.

Izimbangela eziphakeme ze-troponin

Yize ukukhuphuka kwamazinga e-troponin ngokuvamile kuyinkomba yokuhlaselwa yisifo senhliziyo, kunezizathu eziningi zokuthi kungani amazinga angakhuphuka.

Ezinye izinto ezingaba nomthelela kumazinga aphezulu we-troponin afaka:

• ukuzivocavoca okukhulu
• ukusha
• ukutheleleka okubanzi, njenge-sepsis
• imithi
• myocarditis, ukuvuvukala kwemisipha yenhliziyo
• i-pericarditis, ukuvuvukala okuzungeze isikhwama senhliziyo
• i-endocarditis, ukutheleleka kwama-valve wenhliziyo
• i-cardiomyopathy, inhliziyo ebuthakathaka
• ukuhluleka kwenhliziyo
• isifo sezinso
• embolism yamaphaphu, ihlule legazi emaphashini akho
• isifo sikashukela
• i-hypothyroidism, i-thyroid engasebenzi
• unhlangothi
• ukopha emathunjini

Yini ongayilindela ngesikhathi sokuhlolwa

Amazinga eTroponin alinganiswa ngokuhlolwa kwegazi okujwayelekile. Umhlinzeki wezokunakekelwa kwempilo uzothatha isampuli yegazi lakho emthanjeni osengalweni noma esandleni sakho. Ungalindela ubuhlungu obuthambile futhi mhlawumbe ukuphuma kwegazi okuncane.

Udokotela wakho uzoncoma lokhu kuhlolwa uma uhlangabezana nobuhlungu besifuba noma izimpawu ezihlobene nokuhlaselwa yinhliziyo kufaka phakathi:

• ubuhlungu entanyeni, emuva, engalweni, noma emhlathini
• ukujuluka okukhulu
• ubumhlophe
• isiyezi
• isicanucanu
• ukuphelelwa umoya
• ukukhathala

Ngemuva kokuthatha isampula yegazi, umhlinzeki wakho wezokunakekelwa kwempilo uzohlola amazinga akho e-troponin ukuthola ukuhlaselwa yinhliziyo. Bazophinde babheke noma yiziphi izinguquko ku-electrocardiogram (EKG), okulandela umkhondo kagesi wenhliziyo yakho. Lezi zivivinyo zingaphindwa izikhathi eziningana esikhathini samahora angama-24 ukubheka ushintsho. Sebenzisa ukuhlolwa kwe-troponin maduze kungakhipha okungelona iqiniso. Amazinga akhuphukile we-troponin angathatha amahora ngaphambi kokutholakala.

Uma amazinga akho e-troponin ephansi noma ejwayelekile ngemuva kokuzwa ubuhlungu besifuba, kungenzeka ukuthi awukaze uhlaselwe yisifo senhliziyo. Uma amazinga akho ebonakala noma ephezulu, amathuba okulimala kwenhliziyo noma okuhlaselwa yinhliziyo kuphezulu.

Ngaphezu kokulinganisa amazinga wakho we-troponin nokuqapha i-EKG yakho, umhlinzeki wakho wezokunakekelwa kwempilo angafuna ukwenza ezinye izivivinyo ukuhlola impilo yakho, kufaka phakathi:

• ukuhlolwa kwegazi okungeziwe ukukala amazinga enzyme yenhliziyo
• ukuhlolwa kwegazi kwezinye izimo zezokwelapha
• i-echocardiogram, i-ultrasound yenhliziyo
• iX-ray yesifuba
• ukuskena kwe-computed tomography (CT)

Umbono

I-Troponin yiprotheni ekhishwe egazini lakho ngemuva kokuhlaselwa yisifo senhliziyo. Amazinga aphezulu we-troponin angaba izinkomba zezinye izimo zenhliziyo noma izifo, futhi. Ukuzixilonga akukaze kunconywe. Bonke ubuhlungu besifuba kufanele buhlolwe egumbini lezimo eziphuthumayo.

Uma uqala ukuzwa ubuhlungu besifuba noma usola ukuthi unesifo senhliziyo, shayela ku-911. Ukuhlaselwa yinhliziyo nezinye izimo zenhliziyo kungabulala. Izinguquko zendlela yokuphila nokwelashwa kungathuthukisa impilo yenhliziyo futhi kukunikeze impilo esezingeni eliphakeme. Bheka amathiphu ethu okugcina inhliziyo yakho iphilile.