Ukuqonda i-Secondary-Progressive Multiple Sclerosis

-Delile

• Yini i-SPMS?
• I-MS ebuyisela emuva kabusha iba kanjani yi-SPMS
• Ukuhlonza i-SPMS
• Ukwelapha i-SPMS
• Ukuhlolwa kwemitholampilo
• Intuthuko
• Izinguquko
• Isikhathi sokuphila
• I-Outlook ye-SPMS

Yini i-SPMS?

I-Secondary-progressive multiple sclerosis (SPMS) iwuhlobo lwe-multiple sclerosis. Kubhekwa njengesigaba esilandelayo ngemuva kokuphindisela kabusha i-MS (RRMS).

Nge-SPMS, azisekho izimpawu zokuxolelwa. Lokhu kusho ukuthi isimo siya ngokuya siba sibi naphezu kokwelashwa. Kodwa-ke, ukwelashwa kusanconywa kwesinye isikhathi ukusiza ukunciphisa ukuhlaselwa futhi ngethemba ukuthi kunciphisa ukuqhubeka kokukhubazeka.

Lesi sigaba sivamile. Eqinisweni, abantu abaningi abane-MS bazokwakha i-SPMS ngesinye isikhathi uma kungenjalo ekwelashweni okuphumelelayo kokuguqula izifo (i-DMT). Ukwazi izimpawu ze-SPMS kungakusiza ukuthi uyithole kusenesikhathi. Uma nje ukwelashwa kwakho kuqala, udokotela wakho uzokwazi kangcono ukukusiza wehlise izimpawu ezintsha kanye nokuba sibi kwesifo sakho.

I-MS ebuyisela emuva kabusha iba kanjani yi-SPMS

I-MS yisifo esingalapheki sokuzimela komzimba esiza ngezindlela ezahlukahlukene futhi sithinta abantu ngokwehlukile. NgokukaJohns Hopkins Medicine, cishe amaphesenti angama-90 alabo abane-MS baqale batholwe bene-RRMS.

Esigabeni se-RRMS, izimpawu zokuqala ezibonakalayo zifaka:

• ukuba ndikindiki noma ukuhayiza
• ukungasebenzi (izinkinga zokulawula isinye)
• izinguquko embonweni
• ubunzima bokuhamba
• ukukhathala ngokweqile

Izimpawu ze-RRMS zingafika zidlule. Abanye abantu kungenzeka bangabi nazimpawu amasonto noma izinyanga ezimbalwa, into ebizwa ngokuthi ukuxolelwa. Izimpawu ze-MS zingabuya futhi, yize lokhu kubizwa ngokuthi yi-flare-up. Abantu bangabuye bahlakulele izimpawu ezintsha. Lokhu kubizwa ngokuthi ukuhlaselwa, noma ukubuyela emuva.

Ukubuyela emuva ngokuvamile kuthatha izinsuku ezimbalwa kuya emavikini ambalwa. Izimpawu zingakhula kancane kancane ekuqaleni bese zithuthuka kancane kancane ngokuhamba kwesikhathi ngaphandle kokwelashwa noma ngokushesha nge-IV steroids. Ama-RRMS awanakulindeleka.

Ngesinye isikhathi, abantu abaningi abane-RRMS abasenazo izikhathi zokuxolelwa noma ukubuyela emuva okungazelelwe. Esikhundleni salokho, izimpawu zabo ze-MS ziyaqhubeka futhi ziba zimbi ngaphandle kwekhefu.

Izimpawu eziqhubekayo, eziya ziba zimbi zikhomba ukuthi i-RRMS isidlulele ku-SPMS. Lokhu kuvame ukwenzeka eminyakeni eyi-10 kuye kwengu-15 ngemuva kwezimpawu zokuqala ze-MS. Kodwa-ke, i-SPMS ingabambezeleka noma ingavinjelwa uma iqalwe kuma-MS DMTs asebenzayo ekuqaleni kwesifundo sesifo.

Izimpawu ezifanayo zikhona kuzo zonke izinhlobo ze-MS. Kodwa izimpawu ze-SPMS ziyaqhubeka futhi azithuthuki ngokuhamba kwesikhathi.

Ngesikhathi sokuqala kwe-RRMS, izimpawu ziyabonakala, kepha azinzima ngokwanele ukuthi zingaphazamisa imisebenzi yansuku zonke. Lapho i-MS iqhubekela esigabeni sesibili esiqhubekayo, izimpawu ziba nzima kakhulu.

Ukuhlonza i-SPMS

I-SPMS ikhula njengomphumela wokulahleka kwe-neuronal kanye ne-atrophy. Uma ubona izimpawu zakho ziba zimbi kakhulu ngaphandle kokuxolelwa noma ukubuyela emuva okubonakalayo, ukuskena kwe-MRI kungasiza ekuxilongweni.

Ukuskena kwe-MRI kungakhombisa izinga lokufa kwamaseli kanye ne-atrophy yobuchopho. I-MRI izokhombisa ukungafani okwedlulele ngesikhathi sokuhlaselwa ngoba ukuvuza kwama-capillaries ngesikhathi sokuhlaselwa kubangela ukutholwa okukhulu kwedayi ye-gadolinium esetshenziswe kuma-MRI scan.

Ukwelapha i-SPMS

I-SPMS iphawulwa ngokungabikho kokuphindelela, kepha kusenokwenzeka ukuba nokuhlaselwa kwezimpawu, okwaziwa nangokuthi yi-flare-up. Ama-flare-ups ngokuvamile aba mabi kakhulu ekushiseni nangezikhathi zokuxineka.

Njengamanje, kukhona ama-DMTs ayi-14 asetshenziselwa amafomu abuyela emuva we-MS, kufaka phakathi i-SPMS eqhubeka nokubuyela emuva.Uma ngabe ubuthatha eyodwa yalezi zidakamizwa ukwelapha i-RRMS, udokotela wakho angakuthola kuyo aze ayeke ukulawula ukusebenza kwezifo.

Ezinye izinhlobo zokwelashwa zingasiza ukuthuthukisa izimpawu nekhwalithi yempilo. Lokhu kufaka phakathi:

• ukwelashwa ngokomzimba
• ukwelashwa emsebenzini
• ukuvivinya umzimba ngokulingene
• ukuvuselelwa kwengqondo

Ukuhlolwa kwemitholampilo

Ukuhlolwa kwemitholampilo kuvivinya izinhlobo ezintsha zemithi nezindlela zokwelapha kumavolontiya ukuze kuthuthukiswe ukwelashwa kwe-SPMS. Le nqubo inikeza abacwaningi umuzwa ocacile wokuthi yini ephumelelayo nephephile.

Amavolontiya ezivivinyweni zemitholampilo angaba phakathi kwabokuqala ukuthola ukwelashwa okusha, kodwa kunengozi ethile ebandakanyekayo. Ukwelashwa kungahle kungasizi nge-SPMS, futhi kwezinye izimo, kungahle kube nemiphumela emibi kakhulu.

Okubalulekile, kufanele kube nezinyathelo zokuqapha ukugcina amavolontiya ephephile, kanye nokuvikela imininingwane yabo.

Abahlanganyeli ezivivinyweni zokwelashwa ngokuvamile badinga ukuhlangabezana nemihlahlandlela ethile. Lapho uthatha isinqumo sokuthi uzobamba iqhaza yini, kubalulekile ukubuza imibuzo efana nokuthi icala lizohlala isikhathi esingakanani, imiphumela emibi engaba khona ingafaka ini, nokuthi kungani abacwaningi bacabanga ukuthi kuzosiza.

Iwebhusayithi yeNational Multiple Sclerosis Society ibala izivivinyo zokwelashwa e-United States, yize ubhadane lwe-COVID-19 kungenzeka lubambezele izifundo ezihleliwe.

Ukuhlolwa komtholampilo njengamanje okusohlwini lokuqashwa kufaka phakathi eyodwa ye-simvastatin, enganciphisa ukuqhubeka kwe-SPMS, kanye nocwaningo lokuthi ngabe izinhlobo ezahlukahlukene zokwelashwa zingasiza yini abantu abane-MS ukuphatha izinhlungu.

Olunye uvivinyo luhlose ukuhlola ukuthi ngabe i-lipoic acid ingasiza yini abantu abane-MS eqhubekayo ukuthi bahlale beselula futhi bavikele ubuchopho.

Futhi isivivinyo somtholampilo sihlelelwe ukuqeda ngokuhamba kwesikhathi kulo nyaka wamaseli eNurOwn. Umgomo wayo ukuhlola ukuphepha nokusebenza kahle kokwelashwa kwe-stem cell kubantu abane-MS eqhubekayo.

Intuthuko

Ukuqhubekela phambili kubhekisa ezimpawu eziba zimbi ngokulinganayo ngokuhamba kwesikhathi. Kwamanye amaphuzu, i-SPMS ingachazwa ngokuthi "ngaphandle kokuqhubekela phambili," okusho ukuthi kubonakala ngathi ayimbi ngokulinganayo.

Ukuqhubekela phambili kuyehluka kakhulu phakathi kwabantu abane-SPMS. Ngokuhamba kwesikhathi, abanye bangadinga ukusebenzisa isihlalo esinamasondo, kodwa abantu abaningi basakwazi ukuhamba, mhlawumbe besebenzisa induku noma i-walker.

Izinguquko

Izinguquko ziyimigomo ekhombisa ukuthi ngabe i-SPMS yakho iyasebenza noma ayisebenzi. Lokhu kusiza ukwazisa izingxoxo nodokotela wakho mayelana nokwelashwa okungenzeka nokuthi yini ongayilindela ukuya phambili.

Isibonelo, esimweni se-SPMS esisebenzayo, ungaxoxa ngezindlela ezintsha zokwelashwa. Ngokuphambene nalokho, ngomsebenzi ongekho, wena nodokotela wakho ningaxoxa ngokusebenzisa ukuvuselelwa nezindlela zokuphatha izimpawu zakho mhlawumbe nge-DMT enobungozi obuncane.

Isikhathi sokuphila

Isilinganiso seminyaka yokuphila kwabantu abane-MS sithatha ukuba yiminyaka engaba ngu-7 sifushane kunabantu bonke. Akucaci ngokuphelele ukuthi kungani.

Ngaphandle kwamacala abucayi e-MS, angavamile, izimbangela ezinkulu zibukeka njengezinye izimo zezempilo ezithinta abantu ngokuvamile, njengomdlavuza nesifo senhliziyo nesamaphaphu.

Okubalulekile, isikhathi sokuphila sabantu abane-MS sikhuphukile emashumini eminyaka amuva nje.

I-Outlook ye-SPMS

Kubalulekile ukwelapha i-MS ukuze ulawule izimpawu futhi wehlise ukwanda kokukhubazeka. Ukuthola nokwelapha i-RRMS kusenesikhathi kungasiza ekuvimbeleni ukuqala kwe-SPMS, kodwa alikho ikhambi.

Yize lesi sifo sizoqhubeka, kubalulekile ukwelapha i-SPMS ngokushesha okukhulu. Alikho ikhambi, kepha i-MS ayibulali, futhi izindlela zokwelapha zingalithuthukisa kakhulu izinga lempilo. Uma une-RRMS futhi ubona izimpawu eziya ziba zimbi, sekuyisikhathi sokukhuluma nodokotela wakho.