Iyini isiko lomchamo nge-antibiotic, yenziwa kanjani futhi yenzelwe ini

-Delile

• Yini injongo yesiko lomchamo nge-antibiotic
• Uwuqonda kanjani umphumela
• Ukulima nge-antibiotic ye Escherichia coli
• Kwenziwa kanjani

I-Uroculture ene-antibiotic ukuhlolwa okwenziwa elabhorethri okuhlose ukukhomba okuncane okudala ukutheleleka komgudu womchamo nokuthi iyini iphrofayili yayo yokuzwela nokumelana namagciwane ngokuvamile asetshenziselwa ukwelapha ukutheleleka. Ngakho-ke, kusukela kumphumela wokuhlolwa, udokotela angakhombisa i-antimicrobial efanelekile kakhulu yomuntu.

Ukusebenza kwalokhu kuhlolwa kuvame ukukhonjiswa lapho umuntu ekhombisa izimpawu nezimpawu zokutheleleka komchamo, kepha kungacelwa futhi lapho ngemuva kokuhlolwa kohlobo lomchamo i-I, i-EAS, amabhaktheriya kanye nama-leukocyte amaningi emchameni, lokhu ngoba lezi zinguquko akhombisa ukutheleleka komchamo, kubalulekile ukukhomba i-microorganism enomthwalo wemfanelo.

Yini injongo yesiko lomchamo nge-antibiotic

Ukuhlolwa kwesiko lomchamo nge-antibiotic kusebenza ukukhomba i-microorganism ebhekene noshintsho lomchamo nokuthi imiphi imishanguzo yokulwa namagciwane engasetshenziswa kahle empini yayo.

Lokhu kuhlolwa kukhonjiswa ikakhulukazi uma kwenzeka ukutheleleka komchamo, futhi kunga-odwa ngemuva komphumela wokuhlolwa komchamo wohlobo 1, i-EAS, noma lapho umuntu enezimpawu zokutheleleka ngomchamo, njengobuhlungu nokushisa lapho uchama futhi ufisa kaningi ukuba noPee. Yazi ukuthi ungazibona kanjani izimpawu zokutheleleka ngomgudu womchamo.

Lokhu kuhlolwa kusetshenziselwa ukukhomba ubukhona kanye nephrofayili yokuzwela kuma-antimicrobial ezinye zezinto ezincane, okuyinhloko:

• Escherichia coli;
• UKlebsiella pneumoniae;
• UCandida sp.;
• Ama-Proteus mirabilis;
• Pseudomonas spp.;
• I-Staphylococcus saprophyticus;
• I-Streptococcus agalactiae;
• I-Enterococcus faecalis;
• Serratia marcenses;
• Morganella morganii;
• I-Acinetobacter baumannii.

Ukuhlonza amanye ama-microorganisms angahle ahlobene nokutheleleka komgudu womchamo, njenge I-Chlamydia trachomatis, I-Neisseria gonorrhoeae, I-Mycoplasma spp. futhi I-Gardnerella vaginalis, ngokwesibonelo, isikhathi esiningi akwenziwa ngesiko lomchamo, lapho-ke kuyaye kucelwe ukuthi kuqoqwe uketshezi lwesitho sangasese sowesifazane noma se-penile ukuze i-microorganism ibonakale kanye ne-antibiotic, noma ukuhlaziywa komchamo ngezindlela zamangqamuzana.

Uwuqonda kanjani umphumela

Umphumela wesiko lomchamo eline-antibiotic unikezwa ngendlela yombiko, lapho kukhonjiswa khona ukuthi ngabe ukuhlolwa kubi noma akulungile futhi, kulezi zimo, okukhonjwe ngamagciwane amancane, ubuningi bawo emchameni nasemithini elwa namagciwane ibizwela futhi imelana nayo.

Umphumela uthathwa njengongemuhle lapho kunokukhula kuphela kwamanani ejwayelekile wamagciwane amancane ngokwemvelo ayingxenye yohlelo lomchamo. Ngakolunye uhlangothi, umphumela uba muhle uma kukhona ukwanda kwenani lanoma yiziphi izinto ezincane eziyingxenye ye-microbiota ejwayelekile noma lapho ukutholakala kwegciwane elingajwayelekile kuqinisekiswa.

Mayelana ne-antibiotic, ngaphezu kokwazisa ukuthi ngabe i-microorganism iyazwela noma ayizweli kuma-antibiotic, ibuye ikhombise ne-Minimum Inhibitory Concentration, ebizwa nangokuthi i-CMI noma i-MIC, ehambelana nokuhlungwa okuncane kwe-antibiotic ekwaziyo ukuvimbela ukukhula kwamagciwane, ukuba lolu lwazi olubaluleke kakhulu kudokotela ukukhombisa ukwelashwa okufanele kakhulu.

[gqamisa-ukubuyekeza-ukugqamisa]

Ukulima nge-antibiotic ye Escherichia coli

THE Escherichia coli, obeye aziwe njengo E. coli, yigciwane elivame ukuhlotshaniswa nezifo zomchamo. Uma isiko lomchamo lilungile kubhaktheriya, inani eliboniswe emchameni, okuvamise ukuba ngaphezu kwamakholoni ayi-100 000, liyakhonjiswa kulo mbiko, nokuthi imishanguzo izwela kuphi, okujwayele ukuba yiPhosphomycin, Nitrofurantoin, Amoxicillin eneClavulonate, iNorfloxacino noma iCiprofloxacino.

Ngaphezu kwalokho, i-MIC iyakhonjiswa, okuthi uma kwenzeka Escherichia coli, ngokwesibonelo, kunqunywa ukuthi i-MIC ye-Ampicillin engaphansi noma elingana no-8 µg / mL ikhombisa ukuthambekela kwe-antibiotic, futhi ukusetshenziswa kwayo ekwelapheni kunconyiwe, kuyilapho amanani alingana noma ngaphezulu kuka-32 µg / mL khombisa ukuthi amabhaktheriya ayazweli.

Ngakho-ke, ngokwemiphumela etholwe yisiko lomchamo kanye ne-antibiotic, udokotela angakhombisa ukwelashwa okungcono kakhulu kokutheleleka.

Kwenziwa kanjani

Ukuhlolwa kwesiko lomchamo ukuhlolwa okulula okwenziwa kusampula yomchamo, okumele iqoqwe futhi igcinwe esitsheni esifanelekile esihlinzekwa ilebhu. Ukwenza iqoqo, kuyadingeka ukuthi uqale uhlanze indawo esondelene ngensipho namanzi bese uqoqa umchamo wokuqala wosuku, futhi umuntu kufanele anganaki umchamo wokuqala womchamo bese eqoqa ukusakazwa okuphakathi.

Kubalulekile ukuthi isampuli iyiswe elabhorethri kungakapheli amahora amabili ukuze ikwazi ukusebenziseka kusiko lomchamo ne-antibiotic. Elabhorethri, isampula lifakwa endaweni yamasiko ethanda ukukhula kwama-microorganism ajwayelekile akhona emchameni. Ngemuva kwe-24h kuya ku-48h, kungenzeka ukuqinisekisa ukukhula kwama-microorganism futhi, ngakho-ke, kungenzeka ukwenza izivivinyo zokuhlonza ama-microbial.

Ngaphezu kwalokho, kusukela ngesikhathi lapho kubonakala khona ukukhula kwamagciwane esikhungweni samasiko, kungenzeka ukubheka inani lamagciwane, futhi kungakhonjiswa ukuthi kuyikoloni noma ukutheleleka, ngaphezu kokuthi kungenzeka futhi ukwenza i-antibiotic , lapho i-microorganism ihlolwe khona ngama-antibiotic ahlukahlukene, ihlolwe ukuthi yimaphi ama-antibiotics azwelayo noma amelana nawo. Qonda kabanzi nge-antibiogram.