I-Prurigo Nodularis nesikhumba sakho

-Delile

• Izimpawu
• Izithombe
• Ukwelashwa
• Izidakamizwa eziphezulu
• Imijovo
• Imithi ehlelekile
• Ezinye izindlela zokwelapha
• Ukwelashwa okusha
• Imibono eminingi yokuphatha i-PN yakho
• Ukusekela
• Izimbangela
• Amaqiniso asheshayo
• Ukuvimbela
• Ukuthatha

I-Prurigo nodularis (PN) ukuqubuka kwesikhumba okulimaza kakhulu. Amaqhubu e-PN esikhunjeni angaba ngosayizi ukusuka kokuncane kakhulu kuye cishe kububanzi obuyisigamu sentimitha ububanzi. Inani lamaqhubu lingahluka kusuka ku-2 kuye ku-200.

Umcabango ojwayelekile ngukuthi kwenzeka njengokunwaya isikhumba. Isikhumba esilumayo singaba ngenxa yezizathu eziningi, njenge:

• isikhumba esomile
• ukungasebenzi kwegilo
• isifo esingapheliyo sezinso

Ukulunywa kwe-PN kungakhungathekisa kakhulu. Kucatshangwa ukuthi kunokuqina kokulunywa okuphezulu kunanoma isiphi isimo sokulunywa kwesikhumba.

Ukunwaya kwenza ukulunywa kube kubi kakhulu futhi kungadala ukuthi kuvele amaqhuqhuvana amaningi futhi kubhebhethekise amaqhubu akhona.

I-PN inselele ukuyelapha. Ake sibheke izimpawu nezindlela zokuphatha i-PN.

Izimpawu

I-PN ingaqala njengesigaxa esincane, esibomvu esilumayo. Kwenzeka njengokunwaya isikhumba. Amagqabha avame ukuqala ezingalweni noma emilenzeni yakho kodwa futhi angavela kuwo wonke umzimba wakho, noma yikuphi lapho uzikrwebha khona.

Amaqhuqhuva angaluma kakhulu. Amabhampa angaba:

• kanzima
• uqweqwe nosisi
• umbala uhluka kusuka kumathoni wenyama kuya kupinki, nsundu, noma mnyama
• ukhwekhwe
• Warty ngifuna

Isikhumba esiphakathi kwamaqhuqhuva singasoma. Abanye abantu abane-PN nabo bathola ukuhluka okushisayo, okuhlabayo, nokushisa kuma-bumps, ngokusho kokubuyekezwa kuka-2019.

Amabhamu angakha izifo zesibili kusuka ekuklwebheni njalo.

Ukulunywa okukhulu kungaba buthakathaka, kuvimbele ukulala ngokwanele nokuphazamisa inqubo yakho yansuku zonke. Lokhu nakho kungenza abantu abane-PN bazizwe becindezelekile futhi becindezelekile.

Amabhampa angaxazululeka uma umuntu eyeka ukuziklwebha. Bangashiya izibazi kwezinye izimo.

Izithombe

Ukwelashwa

Inhloso yokwelashwa kwe-PN ukugqashula umjikelezo wokunwaya ngokunciphisa ukulunywa.

Umhlinzeki wakho wezokunakekelwa kwempilo uzodinga ukwelapha noma isiphi isimo esingaphansi esidala ukulunywa kwakho nokunwaya.

Ukwelashwa okujwayelekile kwe-PN kubandakanya kokubili okhilimu bezinhloko kanye nezidakamizwa zesistimu yokusiza ukulunywa.

Ngoba ukulunywa kubi kakhulu futhi icala ngalinye lihlukile, kungadingeka ukuthi uzame uchungechunge lwezindlela zokwelashwa ezahlukahlukene ukuthola ukuthi yini okukusebenzela kangcono.

I-PN yisifo esingafundwanga.

Kwabanye abantu, asikho isizathu esingakhomba sokulunywa. Kulaba bantu, akukho ukwelashwa okukodwa okuphumelelayo.

Njengamanje, i-U.S. Food and Drug Administration (FDA) ayikagunyazi noma yiziphi izindlela zokwelapha ukwelapha i-PN. Kodwa-ke, kunezidakamizwa eziningi eziphenywayo ezingasetshenziswa ngaphandle kwelebula ukwelapha lesi simo.

Qiniseka ukuthi uxoxa ngemiphumela engemihle yemithi futhi usebenzise imithi engekho ilebula nomhlinzeki wakho wezokunakekelwa kwempilo.

Izidakamizwa eziphezulu

Umhlinzeki wakho wezokunakekelwa kwempilo angase asikisele ezinye ze-over-the-counter (i-OTC) noma izixazululo zemithi yokwelapha ukuze kunciphise ukulunywa nokupholisa isikhumba sakho.

Izibonelo zingafaka:

• okhilimu be-topical steroid abafana ne-clobetasol noma i-calcineurin inhibitors efana ne-pimecrolimus. (Lokhu kungambozwa ukubasiza ukuthi basebenze ngempumelelo enkulu.)
• itiyela lamalahle elihlosiwe
• amafutha e-topical vitamin D-3 (calcipotriol)
• ukhilimu we-capsaicin
• i-menthol

Imijovo

Umhlinzeki wakho wezokunakekelwa kwempilo angaphakamisa imijovo ye-corticosteroid (Kenalog) yamanye amaqhubu.

Imithi ehlelekile

Umhlinzeki wakho wezokunakekelwa kwempilo angakushela noma aphakamise ama-antihistamines e-OTC ukukusiza ulale ebusuku.

Bangaphinde banikeze imishanguzo esetshenziswa njengama-anti-depressants ukukusiza uyeke ukunwaya. I-Paroxetine ne-amitriptyline kube nempumelelo ekusizeni amaqhubu e-PN ukuba athuthuke.

Ezinye izindlela zokwelapha

Imithi engasiza ukunciphisa amaqhuqhuva nokuqeda ukulunywa ifaka:

• I-Cryotherapy. I-Cryotherapy ukusetshenziswa kwamazinga okushisa abanda kakhulu ku-lesion
• I-Phototherapy. I-Phototherapy isebenzisa ukukhanya kwe-ultraviolet (UV).
• I-Psoralen isetshenziswe ngokuhlangana ne-UV. I-Psoralen ne-UVA ezisetshenziswe ndawonye zaziwa njenge-PUVA.
• I-laser yedayi eqhutshwayo. I-Pulsed dye laser iyindlela yokwelapha esetshenziselwa ukubulala amaseli agulayo.
• Ukwelashwa kwe-Excimer laser. I-excimer laser kuma-nanometer angama-308 ine-PN engaphenduli kwezinye izindlela zokwelapha.

Umhlinzeki wakho wezokunakekelwa kwempilo futhi angasikisela ukwelashwa okuguqula umkhuba ukukusiza uyeke ukunwaya.

Ukwelashwa okusha

Ezinye izilingo ezibandakanya ukusebenzisa izidakamizwa ngaphandle kwelebula zibonise isithembiso ekwehliseni ukulunywa.

• I-naloxone efakwa ngaphakathi kanye ne-naltrexone yomlomo ye-mu-opioid receptor antagonists, engaba nemiphumela emibi yokuqala
• ama-immunosuppressants, afaka phakathi i-cyclosporine ne-methotrexate
• i-gabapentinoids, esetshenziselwa abantu abangaphenduli kwezinye izindlela zokwelapha noma abane-neuropathies ebuhlungu
• i-thalidomide, ekhonjiswe ukuthi iyasebenza, kepha ithathwa njengesixazululo sokugcina ngenxa yemiphumela emibi engaba khona
• I-nalbuphine ne-nemolizumab, manje eseyahlolwa
• isoquercetin, etholakala kwisitshalo iquercetin
• , okuyinto yokwelashwa komjovo

Imibono eminingi yokuphatha i-PN yakho

Isikhumba sawo wonke umuntu sehlukile, futhi kungathatha isikhathi esithile ukuthola inqubo esiza ukulunywa kwakho.

Inhlanganisela yamakhambi ingasebenza kahle kakhulu. Kubalulekile ukuzama ukwephula umjikelezo wokunwaya ukuze uvikele amaqhuqhuva amaningi futhi uvumele amadala ukuxazulula.

Ngaphezu kwemithi enqunyiwe kanye nama-OTC okhilimu:

• Sebenzisa iphakethe leqhwa ukupholisa izindawo ezilumayo.
• Thatha okugeza okusivivi, okufishane nge-colloidal oatmeal.
• Gcoba amafutha ngeVaseline noma ukhilimu we-hypoallergenic.
• Sebenzisa insipho engenamakha neminye imikhiqizo kwesikhumba esibucayi.

Ukusekela

Xhumana neNodular Prurigo International ukuthola eminye imininingwane noma ukujoyina iqembu layo elizimele le-Facebook noma uvule iqembu le-Facebook.

Ukubamba iqhaza esivivinyweni somtholampilo se-PN nakho kuyindlela.

Izimbangela

Isizathu ngqo se-PN asiqondakali ngokuphelele, kodwa izilonda kukholakala ukuthi zingumphumela oqondile wesikhumba esilumayo, okungaba ngenxa yezizathu eziningi.

I-PN ihlotshaniswe nezimo eziningana, kufaka phakathi:

• i-atopic dermatitis (eczema)
• isifo sikashukela
• ukwehluleka kwezinso okungamahlalakhona
• i-hepatitis C engapheli
• ukuphazamiseka kwemizwa
• ukuphazamiseka kwengqondo
• i-post-herpetic neuralgia
• I-lymphoma
• icus licus
• ukuhluleka kwenhliziyo
• isifo esingapheliyo sokuvimbela kwamaphaphu (COPD)
• I-HIV
• eminye imithi yokwelapha umdlavuza (i-pembrolizumab, i-paclitaxel, ne-carboplatin)

Kucatshangwa ukuthi i-PN yenzeka lapho ezinye izimo zibangela ukulunywa okuqhubekayo nokukhuhla (umjikelezo wokunwaya), okuholela kwizilonda zesici.

Noma ngabe isimo esiyisisekelo sixazululiwe, i-PN kuthiwa kwesinye isikhathi iyaqhubeka.

Futhi, ucwaningo lwango-2019 luphawula ukuthi cishe amaphesenti ayi-13 wabantu abane-PN abanazo izifo noma izici ezibekiwe ngaphambili.

Abaphenyi babheka izindlela eziyisisekelo ezibandakanyeka ku-PN, ezibandakanya:

• izinguquko kumaseli esikhumba
• imicu yezinzwa
• izinguquko ze-neuropeptides kanye neuroimmune system

Njengoba imbangela yokuthuthuka kwe-PN iya icaca, abacwaningi balindele ukuthi ukwelashwa okungcono kuzokwenzeka.

Amaqiniso asheshayo

• I-PN ivame kakhulu kubantu abaphakathi kweminyaka engama-20 nengama-60.
• I-PN ithinta abesilisa nabesifazane ngokulinganayo.
• I-PN ayivamile. Kunezifundo ezimbalwa ngokusabalala kwazo noma izehlakalo. Ucwaningo lwango-2018 lweziguli ezingama-909 ezine-PN luthole ukuthi iziguli zase-Afrika zaseMelika bekufanele zibe ne-PN kuneziguli ezimhlophe.

Ukuvimbela

Kuze kwaziwe ukuthi iyiphi imbangela ngqo ye-PN, kunzima ukuyivimba. Ukungasiklwebhi isikhumba kungaba ukuphela kwendlela.

Uma uthambekele ku-PN, ngenxa yofuzo noma isifo esiyimbangela, qapha isikhumba sakho ngokucophelela. Bheka umhlinzeki wezokunakekelwa kwempilo ukuze alashwe noma yikuphi ukulunywa okuhlala isikhathi eside. Zama ukumisa noma yimuphi umjikelezo wokunwaya ngaphambi kokuba uqale.

Amakhambi amaningi angasiza ekunciphiseni ukulunywa ngaphambi kokuba kube nzima ukuphatha.

Ukuthatha

I-PN yisimo sesikhumba esinamandla kakhulu esingakhubaza. Isizathu saso esiqondile asiqondakali ngokuphelele, kodwa kuyaziwa ukuthi sihambisana nezinye izimo eziningana.

Izindlela zokwelapha eziningi zingenzeka, kepha kungathatha isikhashana ukuphatha ngempumelelo i-PN yakho. Kungenzeka ukuthi inhlanganisela yama-topical, izidakamizwa, nezinye izindlela zokwelashwa zizokusebenzela.

Izindaba ezimnandi ukuthi kunemishanguzo emisha yokwelapha engaphansi kokuthuthukiswa futhi iyahlolwa. Njengoba abacwaningi befunda kabanzi ngomshini we-PN, izindlela zokwelashwa ezisebenzayo eziqondisiwe zizothuthukiswa.